CA2252706A1 - Polypeptide conjugates for transporting substances across cell membranes - Google Patents
Polypeptide conjugates for transporting substances across cell membranes Download PDFInfo
- Publication number
- CA2252706A1 CA2252706A1 CA002252706A CA2252706A CA2252706A1 CA 2252706 A1 CA2252706 A1 CA 2252706A1 CA 002252706 A CA002252706 A CA 002252706A CA 2252706 A CA2252706 A CA 2252706A CA 2252706 A1 CA2252706 A1 CA 2252706A1
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- polypeptide
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
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- Organic Chemistry (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1634796P | 1996-05-01 | 1996-05-01 | |
| US2860996P | 1996-10-23 | 1996-10-23 | |
| US60/028,609 | 1996-10-23 | ||
| US60/016,347 | 1996-10-23 | ||
| PCT/US1997/007335 WO1997040854A2 (en) | 1996-05-01 | 1997-04-30 | Polypeptide conjugates for transporting substances across cell membranes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2252706A1 true CA2252706A1 (en) | 1997-11-06 |
Family
ID=26688485
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002252706A Abandoned CA2252706A1 (en) | 1996-05-01 | 1997-04-30 | Polypeptide conjugates for transporting substances across cell membranes |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0966303A2 (enrdf_load_stackoverflow) |
| JP (1) | JP2000509394A (enrdf_load_stackoverflow) |
| AU (1) | AU729643B2 (enrdf_load_stackoverflow) |
| CA (1) | CA2252706A1 (enrdf_load_stackoverflow) |
| WO (1) | WO1997040854A2 (enrdf_load_stackoverflow) |
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| JP2006516948A (ja) * | 2000-11-14 | 2006-07-13 | ニュー リバー ファーマシューティカルズ インコーポレイテッド | 硫酸アバカビルを含有する新規な薬剤化合物および同化合物の製造ならびに使用方法 |
| EP2316468A1 (en) * | 2002-02-22 | 2011-05-04 | Shire LLC | Delivery system and methods for protecting and administering dextroamphetamine |
| BRPI0406647A (pt) | 2003-01-06 | 2005-12-06 | Angiochem Inc | Método para transportar um composto através da barreira sanguìnea do cérebro |
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| PT1859041E (pt) | 2005-02-18 | 2012-06-19 | Angiochem Inc | Moléculas para transportar um composto através da barreira hematoencefálica |
| NZ560799A (en) | 2005-03-03 | 2009-10-30 | Revance Therapeutics Inc | Compositions and methods for topical application and transdermal delivery of an oligopeptide |
| JP2008531732A (ja) | 2005-03-03 | 2008-08-14 | ルバンス セラピュティックス インク． | ボツリヌス毒素の局所塗布及び経皮送達のための組成物及び方法 |
| EP1915161B1 (en) | 2005-07-13 | 2017-04-26 | Sarepta Therapeutics, Inc. | Antisense antibacterial method and compound |
| US8067571B2 (en) | 2005-07-13 | 2011-11-29 | Avi Biopharma, Inc. | Antibacterial antisense oligonucleotide and method |
| CN101262890B (zh) | 2005-07-15 | 2015-08-26 | 安吉奥化学公司 | 抑肽酶多肽作为载体在药物缀合物中的用途 |
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| US9365634B2 (en) | 2007-05-29 | 2016-06-14 | Angiochem Inc. | Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues |
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| EP2143726A1 (en) * | 2008-07-11 | 2010-01-13 | Novosom AG | Nucleic acid comprising zwitterionic nucleotides |
| AU2009304560A1 (en) | 2008-10-15 | 2010-04-22 | Angiochem Inc. | Conjugates of GLP-1 agonists and uses thereof |
| JP5759379B2 (ja) | 2008-12-05 | 2015-08-05 | アンジオケム インコーポレーテッド | ニューロテンシンまたはニューロテンシンアナログおよびその使用 |
| US8592386B2 (en) * | 2008-12-17 | 2013-11-26 | Sarepta Therapeutics, Inc. | Antisense compositions and methods for modulating contact hypersensitivity or contact dermatitis |
| US9173891B2 (en) | 2009-04-20 | 2015-11-03 | Angiochem, Inc. | Treatment of ovarian cancer using an anticancer agent conjugated to an angiopep-2 analog |
| CN102803500B (zh) | 2009-06-05 | 2014-11-19 | 13治疗有限公司 | 免疫调节肽和使用方法 |
| EP2448965A4 (en) | 2009-07-02 | 2015-02-11 | Angiochem Inc | MULTIMEPEPTID CONJUGATES AND ITS USES |
| TWI620756B (zh) | 2010-05-28 | 2018-04-11 | 薩羅塔治療公司 | 具有經修飾之單元間連結及／或末端基團之寡核苷酸類似物 |
| US10017763B2 (en) | 2010-09-03 | 2018-07-10 | Sarepta Therapeutics, Inc. | dsRNA molecules comprising oligonucleotide analogs having modified intersubunit linkages and/or terminal groups |
| US8580748B2 (en) | 2011-04-06 | 2013-11-12 | 13Therapeutics, Inc. | Peptides for the treatment of hearing |
| US20130085139A1 (en) | 2011-10-04 | 2013-04-04 | Royal Holloway And Bedford New College | Oligomers |
| EP2780299A4 (en) | 2011-11-18 | 2015-04-22 | Sarepta Therapeutics Inc | FUNCTION MODIFIED OLIGONUCLEOTIDES AND SUBUNITS THEREOF |
| CA2868174A1 (en) | 2012-03-20 | 2013-09-26 | Sarepta Therapeutics, Inc. | Boronic acid conjugates of oligonucleotide analogues |
| GB201210358D0 (en) * | 2012-06-12 | 2012-07-25 | Polytherics Ltd | Complexes |
| CA2881602A1 (en) | 2012-08-14 | 2014-02-20 | Angiochem Inc. | Peptide-dendrimer conjugates and uses thereof |
| MA41795A (fr) | 2015-03-18 | 2018-01-23 | Sarepta Therapeutics Inc | Exclusion d'un exon induite par des composés antisens dans la myostatine |
| EP3302489A4 (en) | 2015-06-04 | 2019-02-06 | Sarepta Therapeutics, Inc. | METHOD AND COMPOUNDS FOR THE TREATMENT OF DISEASES AND SUFFERING IN CONNECTION WITH LYMPHOCYTES |
| ES2826827T3 (es) | 2015-06-15 | 2021-05-19 | Angiochem Inc | Métodos para el tratamiento de carcinomatosis leptomeníngea |
| KR20180105115A (ko) * | 2015-10-07 | 2018-09-27 | 코르메딕스, 인코포레이티드 | 타우로리딘의 피부-침투성 제제 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1541436A (en) * | 1976-02-02 | 1979-02-28 | Searle & Co | Immunological materials |
| GB9017024D0 (en) * | 1990-08-03 | 1990-09-19 | Erba Carlo Spa | New linker for bioactive agents |
| GB9026491D0 (en) * | 1990-12-05 | 1991-01-23 | Erba Carlo Spa | Anthracycline-conjugates |
| CZ297979B6 (cs) * | 1996-03-12 | 2007-05-16 | Pg-Txl Company, L. P. | Kompozice obsahující protinádorové lécivo konjugované s ve vode rozpustným polymerem, její pouzití pro výrobu léciva a implantovatelná lékarská pomucka |
-
1997
- 1997-04-30 EP EP97923513A patent/EP0966303A2/en not_active Withdrawn
- 1997-04-30 CA CA002252706A patent/CA2252706A1/en not_active Abandoned
- 1997-04-30 JP JP9539221A patent/JP2000509394A/ja not_active Ceased
- 1997-04-30 WO PCT/US1997/007335 patent/WO1997040854A2/en active Application Filing
- 1997-04-30 AU AU29298/97A patent/AU729643B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP0966303A2 (en) | 1999-12-29 |
| AU729643B2 (en) | 2001-02-08 |
| WO1997040854A2 (en) | 1997-11-06 |
| JP2000509394A (ja) | 2000-07-25 |
| WO1997040854A3 (en) | 1998-03-12 |
| AU2929897A (en) | 1997-11-19 |
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