CA2225555A1 - Quinolones and their therapeutic use - Google Patents
Quinolones and their therapeutic use Download PDFInfo
- Publication number
- CA2225555A1 CA2225555A1 CA002225555A CA2225555A CA2225555A1 CA 2225555 A1 CA2225555 A1 CA 2225555A1 CA 002225555 A CA002225555 A CA 002225555A CA 2225555 A CA2225555 A CA 2225555A CA 2225555 A1 CA2225555 A1 CA 2225555A1
- Authority
- CA
- Canada
- Prior art keywords
- ethyl
- dihydro
- oxo
- pyrrolidinyl
- pyrido
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- A61P37/00—Drugs for immunological or allergic disorders
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9515812.7A GB9515812D0 (en) | 1995-08-02 | 1995-08-02 | Novel compounds |
| GB9515812.7 | 1995-08-02 | ||
| GB9523679.0 | 1995-11-20 | ||
| GBGB9523679.0A GB9523679D0 (en) | 1995-11-20 | 1995-11-20 | Novel compounds |
| GB9605865.6 | 1996-03-20 | ||
| GBGB9605865.6A GB9605865D0 (en) | 1996-03-20 | 1996-03-20 | Novel compounds |
| GBGB9611898.9A GB9611898D0 (en) | 1996-06-07 | 1996-06-07 | Quinolones and their therapeutic use |
| GB9611898.9 | 1996-06-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2225555A1 true CA2225555A1 (en) | 1997-02-13 |
Family
ID=27451320
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002225555A Abandoned CA2225555A1 (en) | 1995-08-02 | 1996-07-31 | Quinolones and their therapeutic use |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5753666A (https=) |
| EP (1) | EP0841927B1 (https=) |
| JP (1) | JPH11510156A (https=) |
| AT (1) | ATE258437T1 (https=) |
| AU (1) | AU695132B2 (https=) |
| CA (1) | CA2225555A1 (https=) |
| DE (1) | DE69631423T2 (https=) |
| ES (1) | ES2211965T3 (https=) |
| MX (1) | MX9800921A (https=) |
| WO (1) | WO1997004775A1 (https=) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9605437D0 (en) * | 1996-03-15 | 1996-05-15 | Iaf Biochem Int | Cytomegalovirus inhibiting compounds |
| US6297248B1 (en) | 1997-04-06 | 2001-10-02 | Suntory Limited | 1-aryl-1,8-naphthylidin-4-one derivative as type IV phosphodiesterase inhibitor |
| HUP0002353A3 (en) | 1998-01-29 | 2001-11-28 | Daiichi Asubio Pharma Co Ltd | 1-cycloalkyl-1,8-naphthyridin-4-one derivatives with phoshodiesterase iv inhibitory activity and pharmaceutical compositions containing them |
| AU4849199A (en) * | 1998-07-01 | 2000-01-24 | Celgro | Fungal growth inhibitors |
| US6248739B1 (en) * | 1999-01-08 | 2001-06-19 | Pharmacia & Upjohn Company | Quinolinecarboxamides as antiviral agents |
| JP2003528087A (ja) | 2000-03-21 | 2003-09-24 | ファルマシア・アンド・アップジョン・カンパニー | 抗ウイルス剤としての４−オキソ−１，４−ジヒドロ−３−シンノリンカルボキサミド |
| NZ521522A (en) | 2000-03-21 | 2004-08-27 | Upjohn Co | 4-oxo-1,4-dihydro[1,8]naphthyridine-3-carboxamides useful as antiviral agents |
| JP2003531195A (ja) | 2000-03-21 | 2003-10-21 | ファルマシア・アンド・アップジョン・カンパニー | 抗ウイルス剤としての４−ヒドロキシシンノリン−３−カルボキサミド |
| CA2399991A1 (en) | 2000-03-21 | 2001-09-27 | Pharmacia & Upjohn Company | 4-hydroxy-1,8-naphthyridine-3-carboxamides as antiviral agents |
| PE20011349A1 (es) | 2000-06-16 | 2002-01-19 | Upjohn Co | 1-aril-4-oxo-1,4-dihidro-3-quinolincarboxamidas como agentes antivirales |
| US6559145B2 (en) | 2000-07-12 | 2003-05-06 | Pharmacia & Upjohn Company | Heterocycle carboxamides as antiviral agents |
| US6562822B2 (en) | 2000-07-12 | 2003-05-13 | Pharmacia & Upjohn Company | Heterocyle carboxamides as antiviral agents |
| US6730682B2 (en) * | 2000-07-12 | 2004-05-04 | Pharmacia & Upjohn Company | Heterocycle carboxamides as antiviral agents |
| JP2004517860A (ja) * | 2000-10-12 | 2004-06-17 | メルク エンド カムパニー インコーポレーテッド | Ｈｉｖインテグラーゼ阻害薬として有用なアザ−およびポリアザ−ナフタレニルカルボキサミド類 |
| CA2425440C (en) * | 2000-10-12 | 2010-04-13 | Merck & Co., Inc. | Aza- and polyaza-naphthalenyl carboxamides useful as hiv integrase inhibitors |
| US6919351B2 (en) * | 2000-10-12 | 2005-07-19 | Merck & Co., Inc. | Aza-and polyaza-naphthalenyl-carboxamides useful as HIV integrase inhibitors |
| MXPA03005152A (es) | 2000-12-11 | 2004-10-14 | Tularik Inc | Antogonista de cxcr3. |
| PE20020856A1 (es) * | 2001-02-13 | 2002-11-11 | Aventis Pharma Gmbh | 1,2,3,4-tetrahidronaftil aminas aciladas |
| TWI243164B (en) | 2001-02-13 | 2005-11-11 | Aventis Pharma Gmbh | Acylated indanyl amines and their use as pharmaceuticals |
| JP4460221B2 (ja) * | 2001-05-24 | 2010-05-12 | メルク フロスト カナダ リミテツド | １−ビアリール−１，８−ナフチリジン−４−オン系ホスホジエステラーゼ−４阻害薬 |
| US6794379B2 (en) | 2001-06-06 | 2004-09-21 | Tularik Inc. | CXCR3 antagonists |
| WO2003077857A2 (en) * | 2002-03-15 | 2003-09-25 | Merck & Co., Inc. | N-(substituted benzyl)-8-hydroxy-1,6-naphthyridine-7- carboxamides useful as hiv integrase inhibitors |
| IS7839A (is) * | 2002-11-22 | 2004-05-23 | Merck Frosst Canada Ltd. | 4-oxó-1-(3-setið fenýl-1,4-díhýdró-1,8-naftýridín-3-karboxamíð fosfódíesterasa-4 hindrar |
| WO2005009971A1 (ja) * | 2003-07-24 | 2005-02-03 | Astellas Pharma Inc. | キノロン誘導体又はその塩 |
| RS56037B1 (sr) | 2004-06-24 | 2017-09-29 | Vertex Pharma | Modulatori atp-vezujućih kasetnih transportera |
| US8354427B2 (en) | 2004-06-24 | 2013-01-15 | Vertex Pharmaceutical Incorporated | Modulators of ATP-binding cassette transporters |
| DE102004035203A1 (de) | 2004-07-21 | 2006-02-16 | Bayer Healthcare Ag | Substituierte Chinolone |
| DE102005030524A1 (de) | 2005-06-30 | 2007-01-18 | Aicuris Gmbh & Co. Kg | Substituierte Chinolone II |
| TW200800983A (en) * | 2005-09-14 | 2008-01-01 | Janssen Pharmaceutica Nv | 5-oxo-5,8-dihydro-pyrido-pyrimidines as inhibitors of C-FMS kinase |
| DE602006018057D1 (de) * | 2005-11-10 | 2010-12-16 | Chemocentryx Inc | Substituierte chinolone und verwendungsverfahren |
| EP1979367A2 (en) * | 2005-12-24 | 2008-10-15 | Vertex Pharmaceuticals Incorporated | Quinolin-4-one derivatives as modulators of abc transporters |
| EP3219705B1 (en) | 2005-12-28 | 2020-03-11 | Vertex Pharmaceuticals Incorporated | Pharmaceutical compositions of the amorphous form of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide |
| DE102006005861A1 (de) | 2006-02-09 | 2007-08-23 | Aicuris Gmbh & Co. Kg | Substituierte Chinolone III |
| FR2917413B1 (fr) | 2007-06-13 | 2009-08-21 | Sanofi Aventis Sa | Derives de 7-alkynyl-1,8-naphthyridones, leur preparation et leur application en therapeutique |
| FR2917412B1 (fr) * | 2007-06-13 | 2009-08-21 | Sanofi Aventis Sa | Derives de 7-alkynyl, 1,8-naphthyridones, leur preparation et leur application en therapeutique |
| EP2201010B1 (en) | 2007-09-14 | 2013-11-06 | Vertex Pharmaceuticals Incorporated | Modulators of cystic fibrosis transmembrane conductance regulator |
| US20100074949A1 (en) | 2008-08-13 | 2010-03-25 | William Rowe | Pharmaceutical composition and administration thereof |
| US12458635B2 (en) | 2008-08-13 | 2025-11-04 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administrations thereof |
| EP2196465A1 (en) | 2008-12-15 | 2010-06-16 | Almirall, S.A. | (3-oxo)pyridazin-4-ylurea derivatives as PDE4 inhibitors |
| EP2401275B1 (en) | 2009-02-24 | 2013-07-24 | Respiratorius AB | Naphthyridine derivatives having bronchodilating activity |
| EP2226323A1 (en) | 2009-02-27 | 2010-09-08 | Almirall, S.A. | New tetrahydropyrazolo[3,4-c]isoquinolin-5-amine derivatives |
| PL2408750T3 (pl) | 2009-03-20 | 2016-02-29 | Vertex Pharma | Sposób otrzymywania modulatorów błonowego regulatora przewodnictwa swoistego dla mukowiscydozy |
| EP2380890A1 (en) | 2010-04-23 | 2011-10-26 | Almirall, S.A. | New 7,8-dihydro-1,6-naphthyridin-5(6h)-one-derivatives as PDE4 inhibitors |
| EP2394998A1 (en) | 2010-05-31 | 2011-12-14 | Almirall, S.A. | 3-(5-Amino-6-oxo-1,6-dihydropyridazin-3-yl)-biphenyl derivatives as PDE4 inhibitors |
| US8802700B2 (en) | 2010-12-10 | 2014-08-12 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-Binding Cassette transporters |
| CN102643268B (zh) * | 2011-12-30 | 2014-05-21 | 沈阳药科大学 | 喹啉类及噌啉类化合物及其应用 |
| CA2860672A1 (en) | 2012-01-06 | 2013-07-11 | University Of South Florida | Compositions, methods of use, and methods of treatment |
| JP2015511583A (ja) | 2012-02-27 | 2015-04-20 | バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ | 薬学的組成物およびその投与 |
| CN107250113B (zh) | 2014-10-07 | 2019-03-29 | 弗特克斯药品有限公司 | 囊性纤维化跨膜传导调节蛋白的调节剂的共晶 |
| CN107998131B (zh) * | 2017-12-27 | 2019-09-24 | 湖北工业大学 | 芳香酯类化合物用于制备抗adv-7病毒药物 |
| CN111646941A (zh) * | 2020-07-17 | 2020-09-11 | 天津科技大学 | 一种磺酰胺类衍生物及其制备方法和应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3524858A (en) * | 1967-05-18 | 1970-08-18 | Warner Lambert Pharmaceutical | 1,4 - dihydro-1-substituted alkyl-6,7-methylenedioxy - 4 - oxoquinoline-3-carboxylic acid |
| FR2564832B1 (fr) * | 1984-05-23 | 1987-05-15 | Panmedica Sa | Nouveaux n-acyl derives d'amino-acides et leurs esters, leur procede de preparation et medicaments les contenant |
| US4786644A (en) * | 1987-11-27 | 1988-11-22 | Hoechst-Roussel Pharmaceuticals Inc. | 1-aryl-3-quinolinecarboxamide |
| JPH02124871A (ja) * | 1988-07-27 | 1990-05-14 | Dainippon Pharmaceut Co Ltd | １位が置換された複素環式カルボン酸アミド誘導体 |
-
1996
- 1996-07-31 DE DE69631423T patent/DE69631423T2/de not_active Expired - Fee Related
- 1996-07-31 EP EP96925909A patent/EP0841927B1/en not_active Expired - Lifetime
- 1996-07-31 WO PCT/GB1996/001866 patent/WO1997004775A1/en not_active Ceased
- 1996-07-31 ES ES96925909T patent/ES2211965T3/es not_active Expired - Lifetime
- 1996-07-31 CA CA002225555A patent/CA2225555A1/en not_active Abandoned
- 1996-07-31 AT AT96925909T patent/ATE258437T1/de not_active IP Right Cessation
- 1996-07-31 MX MX9800921A patent/MX9800921A/es not_active IP Right Cessation
- 1996-07-31 JP JP9507375A patent/JPH11510156A/ja not_active Ceased
- 1996-07-31 AU AU66266/96A patent/AU695132B2/en not_active Ceased
- 1996-08-02 US US08/691,339 patent/US5753666A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0841927A1 (en) | 1998-05-20 |
| ATE258437T1 (de) | 2004-02-15 |
| DE69631423D1 (de) | 2004-03-04 |
| JPH11510156A (ja) | 1999-09-07 |
| WO1997004775A1 (en) | 1997-02-13 |
| AU695132B2 (en) | 1998-08-06 |
| MX9800921A (es) | 1998-05-31 |
| US5753666A (en) | 1998-05-19 |
| EP0841927B1 (en) | 2004-01-28 |
| AU6626696A (en) | 1997-02-26 |
| DE69631423T2 (de) | 2004-12-02 |
| ES2211965T3 (es) | 2004-07-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |