CA2224797A1 - Cellule tumorale epitheliale immortalisee - Google Patents
Cellule tumorale epitheliale immortalisee Download PDFInfo
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- CA2224797A1 CA2224797A1 CA002224797A CA2224797A CA2224797A1 CA 2224797 A1 CA2224797 A1 CA 2224797A1 CA 002224797 A CA002224797 A CA 002224797A CA 2224797 A CA2224797 A CA 2224797A CA 2224797 A1 CA2224797 A1 CA 2224797A1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001152—Transcription factors, e.g. SOX or c-MYC
- A61K39/001153—Wilms tumor 1 [WT1]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001102—Receptors, cell surface antigens or cell surface determinants
- A61K39/001103—Receptors for growth factors
- A61K39/001106—Her-2/neu/ErbB2, Her-3/ErbB3 or Her 4/ErbB4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001152—Transcription factors, e.g. SOX or c-MYC
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001154—Enzymes
- A61K39/001164—GTPases, e.g. Ras or Rho
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5152—Tumor cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Oncology (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
L'invention se rapporte à des cellules tumorales épithéliales ayant un potentiel métastatique qui ont intégré dans leur génome ou dans un autre élément génétique de répétition au moins un oncogène immortalisant introduit de façon externe et éventuellement au moins un gène codant un facteur immunostimulateur, qui sont exprimés dans de telles cellules tumorales. En outre, l'invention se rapporte à des anticorps reconnaissant spécifiquement les cellules tumorales épithéliales de cette invention, à des procédés pour la production desdites cellules tumorales ainsi qu'à des compositions pharmaceutiques et de diagnostic comportant respectivement lesdites cellules tumorales et lesdits anticorps. Enfin, l'invention décrit l'utilisation des cellules tumorales épithéliales et/ou anticorps pour la préparation de vaccins antitumoraux et de médicaments pour la prophylaxie et/ou le traitement du cancer et/ou de la métastase du cancer.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP95109860 | 1995-06-23 | ||
| EP95109860.7 | 1995-06-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2224797A1 true CA2224797A1 (fr) | 1997-01-09 |
Family
ID=8219387
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002224797A Abandoned CA2224797A1 (fr) | 1995-06-23 | 1996-06-24 | Cellule tumorale epitheliale immortalisee |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0839183A1 (fr) |
| JP (1) | JPH11507834A (fr) |
| AU (1) | AU6415396A (fr) |
| CA (1) | CA2224797A1 (fr) |
| NO (1) | NO976036L (fr) |
| WO (1) | WO1997000946A1 (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6004791A (en) * | 1996-11-13 | 1999-12-21 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Protein tyrosine phosphatase PTP20 and related products and methods |
| US6921975B2 (en) | 2003-04-18 | 2005-07-26 | Freescale Semiconductor, Inc. | Circuit device with at least partial packaging, exposed active surface and a voltage reference plane |
| CN113789350A (zh) * | 2021-09-08 | 2021-12-14 | 汉姆德(宁波)智能医疗科技有限公司 | 哺乳类食管鳞状上皮永生化细胞系的构建方法、构建的细胞系及其类器官 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3627326A1 (de) * | 1986-08-12 | 1988-02-18 | Boehringer Mannheim Gmbh | Immortalisierung durch dns-uebertragung |
-
1996
- 1996-06-24 EP EP96923904A patent/EP0839183A1/fr not_active Withdrawn
- 1996-06-24 CA CA002224797A patent/CA2224797A1/fr not_active Abandoned
- 1996-06-24 AU AU64153/96A patent/AU6415396A/en not_active Abandoned
- 1996-06-24 WO PCT/EP1996/002747 patent/WO1997000946A1/fr not_active Application Discontinuation
- 1996-06-24 JP JP9503590A patent/JPH11507834A/ja not_active Ceased
-
1997
- 1997-12-22 NO NO976036A patent/NO976036L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0839183A1 (fr) | 1998-05-06 |
| WO1997000946A1 (fr) | 1997-01-09 |
| JPH11507834A (ja) | 1999-07-13 |
| NO976036L (no) | 1998-02-03 |
| AU6415396A (en) | 1997-01-22 |
| NO976036D0 (no) | 1997-12-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued | ||
| FZDE | Discontinued |
Effective date: 20051107 |