CA2214143A1 - Compositions de combinaison contenant benazeprile ou benazeprilat et valsartane - Google Patents

Compositions de combinaison contenant benazeprile ou benazeprilat et valsartane Download PDF

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Publication number
CA2214143A1
CA2214143A1 CA002214143A CA2214143A CA2214143A1 CA 2214143 A1 CA2214143 A1 CA 2214143A1 CA 002214143 A CA002214143 A CA 002214143A CA 2214143 A CA2214143 A CA 2214143A CA 2214143 A1 CA2214143 A1 CA 2214143A1
Authority
CA
Canada
Prior art keywords
active ingredient
valsartan
composition according
ingredient component
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002214143A
Other languages
English (en)
Inventor
Marc De Gasparo
David Saul Cohen
Randy Lee Webb
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2214143A1 publication Critical patent/CA2214143A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/556—Angiotensin converting enzyme inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Abstract

L'invention se rapporte à des compositions de combinaison pharmaceutique pour le traitement de l'hypertension, l'insuffisante cardiaque globale et l'insuffisance rénale, comportant (1) le bénazéprile inhibiteur de ACE de formule (I) ou le bénazéprilat de formule (II) ou un de leurs sels pharmaceutiquement acceptables, et la valsartane antagoniste AT¿1? de formule (III) ou un de leurs sels pharmaceutiquement acceptables, ainsi que les méthodes de traitement de l'hypertension, de l'insuffisance cardiaque globale et de l'insuffisance rénale.
CA002214143A 1995-04-07 1996-04-02 Compositions de combinaison contenant benazeprile ou benazeprilat et valsartane Abandoned CA2214143A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1012/95 1995-04-07
CH101295 1995-04-07

Publications (1)

Publication Number Publication Date
CA2214143A1 true CA2214143A1 (fr) 1996-10-10

Family

ID=4200393

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002214143A Abandoned CA2214143A1 (fr) 1995-04-07 1996-04-02 Compositions de combinaison contenant benazeprile ou benazeprilat et valsartane

Country Status (15)

Country Link
EP (1) EP0820302A1 (fr)
JP (1) JPH11503139A (fr)
KR (1) KR19980703647A (fr)
CN (1) CN1181019A (fr)
AU (1) AU5399096A (fr)
BR (1) BR9604818A (fr)
CA (1) CA2214143A1 (fr)
CZ (1) CZ313897A3 (fr)
HU (1) HUP9801593A2 (fr)
MX (1) MX9707683A (fr)
NO (1) NO974400L (fr)
PL (1) PL322529A1 (fr)
SK (1) SK133897A3 (fr)
TR (1) TR199701121T1 (fr)
WO (1) WO1996031234A1 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11508894A (ja) * 1995-06-30 1999-08-03 メルク エンド カンパニー インコーポレーテッド Ａｃｅ阻害剤とａｉｉ拮抗薬を用いる腎疾患の治療方法
CN101011390A (zh) 1999-01-26 2007-08-08 诺瓦提斯公司 血管紧张素ⅱ受体拮抗剂在治疗急性心肌梗塞中的应用
RU2298418C2 (ru) * 2000-04-12 2007-05-10 Новартис Аг Комбинация по меньшей мере двух соединений, выбранных из групп антагонистов at1-рецептора или ингибиторов асе (ангиотензинпревращающий фермент), или ингибиторов hmg-coa-редуктазы (бета-гидрокси-бета-метилглутарил-кофермент-а-редуктаза)
DK1313714T3 (da) 2000-07-19 2008-12-15 Novartis Ag Valsartansalte
JP2004520268A (ja) * 2000-08-22 2004-07-08 ベーリンガー インゲルハイム ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト アンギオテンシンｉｉ拮抗剤とアンギオテンシンｉ変換酵素阻害剤とを含有する医薬組成物
GB0020691D0 (en) * 2000-08-22 2000-10-11 Boehringer Ingelheim Pharma Pharmaceutical combination
WO2002049645A1 (fr) * 2000-12-18 2002-06-27 Novartis Ag Combinaison therapeutique d'amlodipine et de benazepril
US6869970B2 (en) * 2002-02-04 2005-03-22 Novartis Ag Crystalline salt forms of valsartan
CN100377744C (zh) * 2002-07-05 2008-04-02 安徽省生物医学研究所 一种预测acei类降压药药效的复方药
EP1578360A4 (fr) * 2002-08-28 2009-10-21 Curis Inc Administration conjointe de morphogenes et d'inhibiteurs de conversion de l'enzyme de l'angiotensine pour le traitement de l'insuffisance renale chronique
EP1908469A1 (fr) * 2006-10-06 2008-04-09 Boehringer Ingelheim Vetmedica Gmbh Antagonistes du récepteur de l'angiotensine II pour traiter des désordres sistémiques des chats
CN101869710A (zh) * 2009-04-24 2010-10-27 北京奥萨医药研究中心有限公司 降压药物组合物
SG176585A1 (en) 2009-05-20 2012-01-30 Boehringer Ingelheim Vetmed Pharmaceutical oral telmisartan solution
US20110009347A1 (en) 2009-07-08 2011-01-13 Yin Liang Combination therapy for the treatment of diabetes
CN113144204A (zh) * 2014-01-31 2021-07-23 詹森药业有限公司 用于治疗和预防肾病和脂肪肝病的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2081564C (fr) * 1990-05-11 1998-02-03 Anthony Andrea Fossa Compositions et methodes therapeutiques synergiques
EP0629408A1 (fr) * 1993-06-16 1994-12-21 LABORATOIRES MERCK, SHARP & DOHME-CHIBRET Combination d'inhibiteurs ACE et d'antagonistes AII

Also Published As

Publication number Publication date
JPH11503139A (ja) 1999-03-23
SK133897A3 (en) 1998-02-04
PL322529A1 (en) 1998-02-02
EP0820302A1 (fr) 1998-01-28
BR9604818A (pt) 1998-06-09
CN1181019A (zh) 1998-05-06
NO974400D0 (no) 1997-09-23
WO1996031234A1 (fr) 1996-10-10
CZ313897A3 (cs) 1998-01-14
TR199701121T1 (xx) 1998-03-21
KR19980703647A (ko) 1998-12-05
NO974400L (no) 1997-09-23
AU5399096A (en) 1996-10-23
MX9707683A (es) 1997-12-31
HUP9801593A2 (hu) 1999-01-28

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Legal Events

Date Code Title Description
FZDE Discontinued