CA2211666A1 - Method for detecting nucleic acid sequence variations - Google Patents

Method for detecting nucleic acid sequence variations

Info

Publication number
CA2211666A1
CA2211666A1 CA002211666A CA2211666A CA2211666A1 CA 2211666 A1 CA2211666 A1 CA 2211666A1 CA 002211666 A CA002211666 A CA 002211666A CA 2211666 A CA2211666 A CA 2211666A CA 2211666 A1 CA2211666 A1 CA 2211666A1
Authority
CA
Canada
Prior art keywords
nucleic acid
mismatch
sequence
dna
solid support
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002211666A
Other languages
English (en)
French (fr)
Inventor
Ulf Landegren
Arild Lagerqvist
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2211666A1 publication Critical patent/CA2211666A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C12Q1/683—Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA002211666A 1995-01-30 1996-01-30 Method for detecting nucleic acid sequence variations Abandoned CA2211666A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9500341A SE9500341D0 (sv) 1995-01-30 1995-01-30 Method for detecting DNA sequence variations
SE9500341-4 1995-01-30

Publications (1)

Publication Number Publication Date
CA2211666A1 true CA2211666A1 (en) 1996-08-08

Family

ID=20397030

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002211666A Abandoned CA2211666A1 (en) 1995-01-30 1996-01-30 Method for detecting nucleic acid sequence variations

Country Status (5)

Country Link
EP (1) EP0871766A1 (de)
JP (1) JPH10513055A (de)
CA (1) CA2211666A1 (de)
SE (1) SE9500341D0 (de)
WO (1) WO1996023903A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770370A (en) * 1996-06-14 1998-06-23 David Sarnoff Research Center, Inc. Nuclease protection assays
EP0843019A3 (de) * 1996-11-08 2002-10-09 Kyowa Medex Co., Ltd. Verfahren zur Bestimmung einer spezifischen Nukleinsäuresequenz, und ein Reagenz für diesen Zweck
AU6293798A (en) * 1997-01-29 1998-08-18 Institut Pasteur Polynucleotide associated with the bo or bor syndrome, its corresponding polypeptide and diagnostic and therapeutic applications
EP1051515A2 (de) 1998-01-27 2000-11-15 Cytocell Limited Modifizierte nuklein-säure sonden und dessen verwendungen
US7166432B2 (en) 1999-03-12 2007-01-23 Integragen Compositions and methods for genetic analysis
DE19911130A1 (de) 1999-03-12 2000-09-21 Hager Joerg Verfahren zur Identifikation chromosomaler Regionen und Gene
US20030039964A1 (en) * 2000-05-09 2003-02-27 Giffard Philip Morrison Method
AU2003210259A1 (en) * 2002-02-21 2003-09-09 Nanogen Recognomics Gmbh Method for detecting single nucleotide polymorphisms
AU2003289018A1 (en) * 2002-12-10 2004-07-29 Olympus Corporation Method of analyzing nucleic acid mutation and method of analyzing gene expression

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3919293A (en) * 1992-03-27 1993-11-08 University Of Maryland At Baltimore Detection of gene mutations with mismatch repair enzymes
WO1993022457A1 (en) * 1992-04-24 1993-11-11 Massachusetts Institute Of Technology Screening for genetic variation

Also Published As

Publication number Publication date
JPH10513055A (ja) 1998-12-15
SE9500341D0 (sv) 1995-01-30
WO1996023903A1 (en) 1996-08-08
EP0871766A1 (de) 1998-10-21

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Legal Events

Date Code Title Description
FZDE Dead