CA2191363A1 - Composes chiraux et leur resolution - Google Patents

Composes chiraux et leur resolution

Info

Publication number
CA2191363A1
CA2191363A1 CA 2191363 CA2191363A CA2191363A1 CA 2191363 A1 CA2191363 A1 CA 2191363A1 CA 2191363 CA2191363 CA 2191363 CA 2191363 A CA2191363 A CA 2191363A CA 2191363 A1 CA2191363 A1 CA 2191363A1
Authority
CA
Canada
Prior art keywords
compound
formula
enantiomer
esterase
nitrophenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2191363
Other languages
English (en)
Inventor
Raymond Mccague
Stephen John Clifford Taylor
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chirotech Technology Ltd
Original Assignee
Raymond Mccague
Stephen John Clifford Taylor
Chiroscience Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Raymond Mccague, Stephen John Clifford Taylor, Chiroscience Limited filed Critical Raymond Mccague
Publication of CA2191363A1 publication Critical patent/CA2191363A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/41—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by carboxyl groups, other than cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/86—Oxygen atoms
    • C07D211/88—Oxygen atoms attached in positions 2 and 6, e.g. glutarimide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA 2191363 1994-05-27 1995-05-30 Composes chiraux et leur resolution Abandoned CA2191363A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9410721.6 1994-05-27
GB9410721A GB9410721D0 (en) 1994-05-27 1994-05-27 Chiral compounds and their resolution

Publications (1)

Publication Number Publication Date
CA2191363A1 true CA2191363A1 (fr) 1995-12-07

Family

ID=10755860

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2191363 Abandoned CA2191363A1 (fr) 1994-05-27 1995-05-30 Composes chiraux et leur resolution

Country Status (9)

Country Link
EP (1) EP0763023A1 (fr)
JP (1) JPH10500861A (fr)
CN (1) CN1151731A (fr)
AU (1) AU2572495A (fr)
CA (1) CA2191363A1 (fr)
FI (1) FI964709A (fr)
GB (1) GB9410721D0 (fr)
NO (1) NO965551L (fr)
WO (1) WO1995032947A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1167348A4 (fr) * 1999-03-16 2002-11-13 Eisai Co Ltd Derives de nitrile
US6884791B2 (en) 1999-07-06 2005-04-26 Methylgene, Inc. Inhibitors of β-lactamase
KR100686988B1 (ko) 1999-07-06 2007-02-27 메틸진, 인크. β-락타마제의 술폰아미도메틸 포스포네이트 저해제
WO2006128590A1 (fr) * 2005-05-31 2006-12-07 Dsm Ip Assets B.V. Hydrolases, acides nucleiques codant pour ces hydrolases et methodes de fabrication et d'utilisation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2848455A (en) * 1955-07-18 1958-08-19 Ciba Pharm Prod Inc Alpha-(p-amino-phenyl)-alpha-lower alkyl glutarimides
DE3724520C2 (de) * 1986-07-31 1996-01-11 Madaus Ag Neue 3-Aryl-3-Cycloalkyl-piperidin-2,6-dion-Derivate
JPH06510284A (ja) * 1991-08-22 1994-11-17 カイロサイエンス・リミテッド キラルグルタレートエステル、それらの分割および誘導されるグルタルイミド化合物

Also Published As

Publication number Publication date
NO965551D0 (no) 1996-12-23
FI964709A0 (fi) 1996-11-26
NO965551L (no) 1997-01-09
JPH10500861A (ja) 1998-01-27
FI964709A (fi) 1996-11-26
EP0763023A1 (fr) 1997-03-19
GB9410721D0 (en) 1994-07-13
AU2572495A (en) 1995-12-21
WO1995032947A1 (fr) 1995-12-07
CN1151731A (zh) 1997-06-11

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