JPH10500861A - キラル化合物とその分割 - Google Patents

キラル化合物とその分割

Info

Publication number
JPH10500861A
JPH10500861A JP8500505A JP50050596A JPH10500861A JP H10500861 A JPH10500861 A JP H10500861A JP 8500505 A JP8500505 A JP 8500505A JP 50050596 A JP50050596 A JP 50050596A JP H10500861 A JPH10500861 A JP H10500861A
Authority
JP
Japan
Prior art keywords
formula
compound
enantiomer
ethyl
nitrophenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8500505A
Other languages
English (en)
Japanese (ja)
Inventor
マッケイグ,レイモンド
テイラー,スティーブン・ジョン・クリフォード
Original Assignee
カイロサイエンス・リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by カイロサイエンス・リミテッド filed Critical カイロサイエンス・リミテッド
Publication of JPH10500861A publication Critical patent/JPH10500861A/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/01Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/32Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/41Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by carboxyl groups, other than cyano groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/86Oxygen atoms
    • C07D211/88Oxygen atoms attached in positions 2 and 6, e.g. glutarimide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10Nitrogen as only ring hetero atom
    • C12P17/12Nitrogen as only ring hetero atom containing a six-membered hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP8500505A 1994-05-27 1995-05-30 キラル化合物とその分割 Pending JPH10500861A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9410721A GB9410721D0 (en) 1994-05-27 1994-05-27 Chiral compounds and their resolution
GB9410721.6 1994-05-27
PCT/GB1995/001228 WO1995032947A1 (fr) 1994-05-27 1995-05-30 Composes chiraux et leur resolution

Publications (1)

Publication Number Publication Date
JPH10500861A true JPH10500861A (ja) 1998-01-27

Family

ID=10755860

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8500505A Pending JPH10500861A (ja) 1994-05-27 1995-05-30 キラル化合物とその分割

Country Status (9)

Country Link
EP (1) EP0763023A1 (fr)
JP (1) JPH10500861A (fr)
CN (1) CN1151731A (fr)
AU (1) AU2572495A (fr)
CA (1) CA2191363A1 (fr)
FI (1) FI964709A0 (fr)
GB (1) GB9410721D0 (fr)
NO (1) NO965551L (fr)
WO (1) WO1995032947A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6667412B1 (en) 1999-03-16 2003-12-23 Eisai Co., Ltd. Nitrile compound
WO2001002411A1 (fr) 1999-07-06 2001-01-11 Methylgene Inc. INHIBITEURS SULFONAMIDOMETHYL-PHOSPHONATE DE LA β-LACTAMASE
US6884791B2 (en) 1999-07-06 2005-04-26 Methylgene, Inc. Inhibitors of β-lactamase
WO2006128590A1 (fr) * 2005-05-31 2006-12-07 Dsm Ip Assets B.V. Hydrolases, acides nucleiques codant pour ces hydrolases et methodes de fabrication et d'utilisation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2848455A (en) * 1955-07-18 1958-08-19 Ciba Pharm Prod Inc Alpha-(p-amino-phenyl)-alpha-lower alkyl glutarimides
DE3724520C2 (de) * 1986-07-31 1996-01-11 Madaus Ag Neue 3-Aryl-3-Cycloalkyl-piperidin-2,6-dion-Derivate
JPH06510284A (ja) * 1991-08-22 1994-11-17 カイロサイエンス・リミテッド キラルグルタレートエステル、それらの分割および誘導されるグルタルイミド化合物

Also Published As

Publication number Publication date
AU2572495A (en) 1995-12-21
GB9410721D0 (en) 1994-07-13
WO1995032947A1 (fr) 1995-12-07
NO965551L (no) 1997-01-09
CN1151731A (zh) 1997-06-11
FI964709A (fi) 1996-11-26
NO965551D0 (no) 1996-12-23
CA2191363A1 (fr) 1995-12-07
FI964709A0 (fi) 1996-11-26
EP0763023A1 (fr) 1997-03-19

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