CA2173876C - Alkoxy alkyl carbamates from imidazo(1,2-a)pyridines - Google Patents

Alkoxy alkyl carbamates from imidazo(1,2-a)pyridines Download PDF

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Publication number
CA2173876C
CA2173876C CA002173876A CA2173876A CA2173876C CA 2173876 C CA2173876 C CA 2173876C CA 002173876 A CA002173876 A CA 002173876A CA 2173876 A CA2173876 A CA 2173876A CA 2173876 C CA2173876 C CA 2173876C
Authority
CA
Canada
Prior art keywords
compound
salt
general formula
compounds
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002173876A
Other languages
English (en)
French (fr)
Other versions
CA2173876A1 (en
Inventor
Georg Rainer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Altana Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma AG filed Critical Altana Pharma AG
Publication of CA2173876A1 publication Critical patent/CA2173876A1/en
Application granted granted Critical
Publication of CA2173876C publication Critical patent/CA2173876C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Luminescent Compositions (AREA)
CA002173876A 1993-10-11 1994-10-08 Alkoxy alkyl carbamates from imidazo(1,2-a)pyridines Expired - Fee Related CA2173876C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH304793 1993-10-11
CH3047/93-3 1993-10-11
PCT/EP1994/003326 WO1995010518A1 (de) 1993-10-11 1994-10-08 ALKOXYALKYLCARBAMATE VON IMIDAZO(1,2-a)PYRIDINEN

Publications (2)

Publication Number Publication Date
CA2173876A1 CA2173876A1 (en) 1995-04-20
CA2173876C true CA2173876C (en) 2005-09-27

Family

ID=4247423

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002173876A Expired - Fee Related CA2173876C (en) 1993-10-11 1994-10-08 Alkoxy alkyl carbamates from imidazo(1,2-a)pyridines

Country Status (26)

Country Link
US (1) US5719161A (cs)
EP (1) EP0723544B1 (cs)
JP (1) JP3526305B2 (cs)
KR (1) KR100339059B1 (cs)
CN (1) CN1042633C (cs)
AT (1) ATE200672T1 (cs)
AU (1) AU685176B2 (cs)
BG (1) BG100459A (cs)
CA (1) CA2173876C (cs)
CZ (1) CZ290325B6 (cs)
DE (1) DE59409735D1 (cs)
DK (1) DK0723544T3 (cs)
EE (1) EE03262B1 (cs)
ES (1) ES2157992T3 (cs)
FI (1) FI961564A0 (cs)
GR (1) GR3035943T3 (cs)
HU (1) HU220066B (cs)
NO (1) NO305864B1 (cs)
NZ (1) NZ275419A (cs)
PL (1) PL176424B1 (cs)
PT (1) PT723544E (cs)
RO (1) RO118428B1 (cs)
RU (1) RU2139288C1 (cs)
SK (1) SK283264B6 (cs)
UA (1) UA48122C2 (cs)
WO (1) WO1995010518A1 (cs)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL180278B1 (pl) * 1994-07-28 2001-01-31 Byk Gulden Lomberg Chem Fab Nowe imidazopirydyno-azolidynony, sposób ich wytwarzania oraz srodek farmaceutyczny PL PL PL PL PL PL PL
DE19602855A1 (de) * 1996-01-26 1997-07-31 Byk Gulden Lomberg Chem Fab Neue 3-Methylimidazopyridine
EP0882048B1 (de) * 1996-01-26 2005-05-04 ALTANA Pharma AG 3-alkylimidazopyridine
AU1545297A (en) * 1996-01-26 1997-08-20 Byk Gulden Imidazopyridine halides
SE9802794D0 (sv) * 1998-08-21 1998-08-21 Astra Ab New compounds
US6316020B1 (en) 1999-08-26 2001-11-13 Robert R. Whittle Pharmaceutical formulations
US6262086B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Pharmaceutical unit dosage form
US6780880B1 (en) * 1999-08-26 2004-08-24 Robert R. Whittle FT-Raman spectroscopic measurement
US6312712B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Method of improving bioavailability
US6262085B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6268385B1 (en) 1999-08-26 2001-07-31 Robert R. Whittle Dry blend pharmaceutical formulations
US6369087B1 (en) 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6312723B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Pharmaceutical unit dosage form
US6326384B1 (en) 1999-08-26 2001-12-04 Robert R. Whittle Dry blend pharmaceutical unit dosage form
UA80393C2 (uk) * 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
SE0102808D0 (sv) * 2001-08-22 2001-08-22 Astrazeneca Ab New compounds
DE10145457A1 (de) 2001-09-14 2003-04-03 Basf Ag Substituierte Imidazo[1,2-a]-5,6,7,8-tetrahydropyridin-8-one, Verfahren zu ihrer Herstellung, sowie deren Verwendung zur Herstellung von Imidazo[1,2,-a]pyridinen
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
BRPI0406427B8 (pt) 2003-03-10 2021-05-25 Astrazeneca Ab processo para a preparação de roflumilast
CN1874772A (zh) 2003-11-03 2006-12-06 阿斯利康(瑞典)有限公司 治疗隐匿性胃食管反流的咪唑并[1,2－a]吡啶衍生物
US8663694B2 (en) * 2005-03-16 2014-03-04 Takeda Gmbh Taste masked dosage form containing roflumilast

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU117992A1 (ru) * 1958-04-11 1958-11-30 Н.В. Олехнович Устройство дл отсчета и записи на рассто нии показаний стрелочных приборов
ZA81219B (en) * 1980-01-23 1982-01-27 Schering Corp Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them
US4725601A (en) * 1985-06-04 1988-02-16 Fujisawa Pharmaceutical Co., Ltd. Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers
EP0228006A1 (en) * 1985-12-16 1987-07-08 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridine compounds and processes for preparation thereof
EP0266890A1 (en) * 1986-10-07 1988-05-11 Yamanouchi Pharmaceutical Co. Ltd. Imidazopyridine derivatives, their production, and pharmaceutical compositions containing them
US4831041A (en) * 1986-11-26 1989-05-16 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridine compounds and processes for preparation thereof
GB8722488D0 (en) * 1987-09-24 1987-10-28 Fujisawa Pharmaceutical Co Imidazopyridine compound
JPH02270873A (ja) * 1989-03-13 1990-11-05 Fujisawa Pharmaceut Co Ltd イミダゾピリジン化合物およびその製造法

Also Published As

Publication number Publication date
HK1011681A1 (en) 1999-07-16
EE03262B1 (et) 2000-04-17
HUT73851A (en) 1996-09-30
SK45096A3 (en) 1997-01-08
NO961414L (no) 1996-06-10
CN1134702A (zh) 1996-10-30
US5719161A (en) 1998-02-17
AU7937294A (en) 1995-05-04
ES2157992T3 (es) 2001-09-01
NO305864B1 (no) 1999-08-09
RO118428B1 (ro) 2003-05-30
KR100339059B1 (ko) 2002-11-23
EP0723544B1 (de) 2001-04-18
NO961414D0 (no) 1996-04-10
CZ105596A3 (en) 1996-06-12
ATE200672T1 (de) 2001-05-15
JP3526305B2 (ja) 2004-05-10
PL176424B1 (pl) 1999-05-31
DE59409735D1 (de) 2001-05-23
EP0723544A1 (de) 1996-07-31
HU9600890D0 (en) 1996-06-28
FI961564A7 (fi) 1996-04-10
BG100459A (bg) 1996-11-29
SK283264B6 (sk) 2003-04-01
GR3035943T3 (en) 2001-08-31
CN1042633C (zh) 1999-03-24
AU685176B2 (en) 1998-01-15
WO1995010518A1 (de) 1995-04-20
HU220066B (hu) 2001-10-28
CA2173876A1 (en) 1995-04-20
NZ275419A (en) 1996-12-20
UA48122C2 (uk) 2002-08-15
FI961564L (fi) 1996-04-10
PL313941A1 (en) 1996-08-05
JPH09503515A (ja) 1997-04-08
KR960704890A (ko) 1996-10-09
DK0723544T3 (da) 2001-08-06
CZ290325B6 (cs) 2002-07-17
PT723544E (pt) 2001-09-28
FI961564A0 (fi) 1996-04-10
RU2139288C1 (ru) 1999-10-10

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