CA2161021A1 - Thioindole pyperidinyl derivatives used as antalgics - Google Patents

Thioindole pyperidinyl derivatives used as antalgics

Info

Publication number
CA2161021A1
CA2161021A1 CA002161021A CA2161021A CA2161021A1 CA 2161021 A1 CA2161021 A1 CA 2161021A1 CA 002161021 A CA002161021 A CA 002161021A CA 2161021 A CA2161021 A CA 2161021A CA 2161021 A1 CA2161021 A1 CA 2161021A1
Authority
CA
Canada
Prior art keywords
formula
group
radical
indole
thio
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002161021A
Other languages
English (en)
French (fr)
Inventor
Nicole Francoise Bru-Magniez
Dominique Louis Potin
Jean-Marie Charles Teulon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UPSA SAS
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2161021A1 publication Critical patent/CA2161021A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
CA002161021A 1993-05-18 1994-04-13 Thioindole pyperidinyl derivatives used as antalgics Abandoned CA2161021A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9305966A FR2705346B1 (fr) 1993-05-18 1993-05-18 Nouveaux dérivés de pipéridinyl thio indole, leurs procédés de préparation, compositions pharmaceutiques les contenant, utiles notamment comme antalgiques .
FR9305966 1993-05-18

Publications (1)

Publication Number Publication Date
CA2161021A1 true CA2161021A1 (en) 1994-11-24

Family

ID=9447241

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002161021A Abandoned CA2161021A1 (en) 1993-05-18 1994-04-13 Thioindole pyperidinyl derivatives used as antalgics

Country Status (15)

Country Link
US (1) US5317025A (OSRAM)
EP (1) EP0699195A1 (OSRAM)
JP (1) JPH09500611A (OSRAM)
CN (1) CN1124026A (OSRAM)
AU (1) AU6571594A (OSRAM)
CA (1) CA2161021A1 (OSRAM)
CZ (1) CZ304195A3 (OSRAM)
EE (1) EE9400296A (OSRAM)
FI (1) FI954931A7 (OSRAM)
FR (1) FR2705346B1 (OSRAM)
HU (1) HUT74866A (OSRAM)
MD (1) MD522G2 (OSRAM)
NZ (1) NZ265304A (OSRAM)
TW (1) TW257756B (OSRAM)
WO (1) WO1994026736A1 (OSRAM)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK139593D0 (da) * 1993-12-16 1993-12-16 Lundbeck & Co As H Compounds
JPH10503501A (ja) * 1994-08-03 1998-03-31 アスタ メディカ アクチエンゲゼルシャフト 抗喘息、抗アレルギー、抗炎症及び免疫修飾作用を有するインドール、インダゾール、ピリドピロール及びピリドピラゾール誘導体
US5521196A (en) * 1994-10-05 1996-05-28 Eli Lilly And Company 5-HT1F agonists for the treatment of migraine
PL322843A1 (en) * 1995-03-20 1998-02-16 Lilly Co Eli 5-substituted 3-91,2,3,6-tetrahydropyridin-4-yl)- and 3-9piperydin-4-4-yl0-1h-indoles nevel 5-htif natagonists
TWI328009B (en) 2003-05-21 2010-08-01 Glaxo Group Ltd Quinoline derivatives as phosphodiesterase inhibitors
JP4980928B2 (ja) * 2004-12-24 2012-07-18 プロシディオン・リミテッド Ｇタンパク質共役受容体（ｇｐｒ１１６）作動薬および肥満および糖尿病治療のためのその使用
AU2006264649A1 (en) * 2005-06-30 2007-01-11 Prosidion Limited GPCR agonists
PE20081659A1 (es) * 2007-01-04 2008-10-24 Prosidion Ltd Agonistas de gpcr
AR064736A1 (es) * 2007-01-04 2009-04-22 Prosidion Ltd Agonistas de gpcr
JP2013525490A (ja) * 2010-05-06 2013-06-20 メルク・シャープ・エンド・ドーム・コーポレイション Ｆａａｈのモジュレータとして有用なアザインドール誘導体
MX384804B (es) 2015-07-02 2025-03-14 Horizon Orphan Llc Analogos de cisteamina resistentes a la ado y sus usos.
CN104945305A (zh) * 2015-07-03 2015-09-30 北京石油化工学院 一种实现吲哚类化合物选择性芳巯基化的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB925429A (en) * 1960-04-01 1963-05-08 Irwin Neisler & Co Indole derivatives
US3264311A (en) * 1963-05-02 1966-08-02 Upjohn Co Esters of 3-(aminosulfinyl) indole-2-carboxylic acids

Also Published As

Publication number Publication date
JPH09500611A (ja) 1997-01-21
NZ265304A (en) 1997-02-24
CZ304195A3 (en) 1996-03-13
MD522G2 (ro) 1997-01-31
FI954931A0 (fi) 1995-10-17
CN1124026A (zh) 1996-06-05
FR2705346A1 (fr) 1994-11-25
FR2705346B1 (fr) 1995-08-11
EE9400296A (et) 1996-04-15
MD522F1 (en) 1996-04-30
FI954931L (fi) 1995-11-20
HUT74866A (en) 1997-02-28
FI954931A7 (fi) 1995-11-20
US5317025A (en) 1994-05-31
EP0699195A1 (fr) 1996-03-06
TW257756B (OSRAM) 1995-09-21
AU6571594A (en) 1994-12-12
HU9503281D0 (en) 1996-01-29
WO1994026736A1 (fr) 1994-11-24

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Legal Events

Date Code Title Description
FZDE Discontinued