CA2151506A1 - Procede de production d'un concentre proteique de lactoserum non denature - Google Patents
Procede de production d'un concentre proteique de lactoserum non denatureInfo
- Publication number
- CA2151506A1 CA2151506A1 CA 2151506 CA2151506A CA2151506A1 CA 2151506 A1 CA2151506 A1 CA 2151506A1 CA 2151506 CA2151506 CA 2151506 CA 2151506 A CA2151506 A CA 2151506A CA 2151506 A1 CA2151506 A1 CA 2151506A1
- Authority
- CA
- Canada
- Prior art keywords
- microfiltration
- whey protein
- milk
- protein concentrate
- serum albumin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000000034 method Methods 0.000 title claims abstract description 38
- 108010046377 Whey Proteins Proteins 0.000 title claims abstract description 24
- 235000021119 whey protein Nutrition 0.000 title claims abstract description 23
- 230000008569 process Effects 0.000 title claims abstract description 21
- 102000007544 Whey Proteins Human genes 0.000 title claims abstract description 17
- 239000012141 concentrate Substances 0.000 title claims abstract description 15
- 238000001471 micro-filtration Methods 0.000 claims abstract description 27
- 108010071390 Serum Albumin Proteins 0.000 claims abstract description 13
- 102000007562 Serum Albumin Human genes 0.000 claims abstract description 13
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 claims abstract description 12
- 235000021240 caseins Nutrition 0.000 claims abstract description 12
- 230000001580 bacterial effect Effects 0.000 claims abstract description 11
- 239000005018 casein Substances 0.000 claims abstract description 11
- 235000020185 raw untreated milk Nutrition 0.000 claims abstract description 11
- 238000000108 ultra-filtration Methods 0.000 claims abstract description 7
- 235000013336 milk Nutrition 0.000 claims description 18
- 239000008267 milk Substances 0.000 claims description 18
- 210000004080 milk Anatomy 0.000 claims description 18
- 239000012528 membrane Substances 0.000 claims description 15
- 239000012466 permeate Substances 0.000 claims description 14
- 239000012465 retentate Substances 0.000 claims description 10
- 239000011148 porous material Substances 0.000 claims description 7
- 239000000919 ceramic Substances 0.000 claims description 5
- 108091003079 Bovine Serum Albumin Proteins 0.000 claims description 3
- 229940098773 bovine serum albumin Drugs 0.000 claims description 3
- 238000011026 diafiltration Methods 0.000 claims description 3
- 241000283690 Bos taurus Species 0.000 claims description 2
- 235000020200 pasteurised milk Nutrition 0.000 claims description 2
- 230000009467 reduction Effects 0.000 abstract description 10
- 235000018102 proteins Nutrition 0.000 description 14
- 102000004169 proteins and genes Human genes 0.000 description 14
- 108090000623 proteins and genes Proteins 0.000 description 14
- 238000004925 denaturation Methods 0.000 description 12
- 230000036425 denaturation Effects 0.000 description 12
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 description 12
- 102000011632 Caseins Human genes 0.000 description 10
- 108010076119 Caseins Proteins 0.000 description 10
- 238000009928 pasteurization Methods 0.000 description 9
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 6
- 229960003180 glutathione Drugs 0.000 description 6
- 108010024636 Glutathione Proteins 0.000 description 5
- 241000894006 Bacteria Species 0.000 description 4
- 239000000693 micelle Substances 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 238000000926 separation method Methods 0.000 description 4
- 102000009027 Albumins Human genes 0.000 description 3
- 108010088751 Albumins Proteins 0.000 description 3
- PABVKUJVLNMOJP-WHFBIAKZSA-N Glu-Cys Chemical compound OC(=O)CC[C@H](N)C(=O)N[C@@H](CS)C(O)=O PABVKUJVLNMOJP-WHFBIAKZSA-N 0.000 description 3
- 235000013365 dairy product Nutrition 0.000 description 3
- 235000005911 diet Nutrition 0.000 description 3
- 230000000378 dietary effect Effects 0.000 description 3
- 230000002766 immunoenhancing effect Effects 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 230000000813 microbial effect Effects 0.000 description 3
- 229910052757 nitrogen Inorganic materials 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 230000009885 systemic effect Effects 0.000 description 3
- 108060003951 Immunoglobulin Proteins 0.000 description 2
- 102000004407 Lactalbumin Human genes 0.000 description 2
- 108090000942 Lactalbumin Proteins 0.000 description 2
- 241000699670 Mus sp. Species 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000001962 electrophoresis Methods 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 239000012467 final product Substances 0.000 description 2
- 230000004907 flux Effects 0.000 description 2
- 230000028996 humoral immune response Effects 0.000 description 2
- 102000018358 immunoglobulin Human genes 0.000 description 2
- 238000011534 incubation Methods 0.000 description 2
- 150000002632 lipids Chemical class 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 229920002401 polyacrylamide Polymers 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 210000002966 serum Anatomy 0.000 description 2
- 235000020183 skimmed milk Nutrition 0.000 description 2
- 230000002459 sustained effect Effects 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 235000021241 α-lactalbumin Nutrition 0.000 description 2
- DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 description 2
- RHUYHJGZWVXEHW-UHFFFAOYSA-N 1,1-Dimethyhydrazine Chemical compound CN(C)N RHUYHJGZWVXEHW-UHFFFAOYSA-N 0.000 description 1
- 241000972773 Aulopiformes Species 0.000 description 1
- 101710143931 Beta-lactoglobulin-3 Proteins 0.000 description 1
- 102000004506 Blood Proteins Human genes 0.000 description 1
- 108010017384 Blood Proteins Proteins 0.000 description 1
- 102000015781 Dietary Proteins Human genes 0.000 description 1
- 108010010256 Dietary Proteins Proteins 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 235000005311 Pandanus odoratissimus Nutrition 0.000 description 1
- 240000002390 Pandanus odoratissimus Species 0.000 description 1
- 241001494479 Pecora Species 0.000 description 1
- 208000035109 Pneumococcal Infections Diseases 0.000 description 1
- 241001397306 Proales Species 0.000 description 1
- 239000005862 Whey Substances 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000001413 amino acids Chemical group 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 101150099875 atpE gene Proteins 0.000 description 1
- 101150018639 atpFH gene Proteins 0.000 description 1
- 101150048329 atpH gene Proteins 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000012888 bovine serum Substances 0.000 description 1
- 229960001506 brilliant green Drugs 0.000 description 1
- HXCILVUBKWANLN-UHFFFAOYSA-N brilliant green cation Chemical compound C1=CC(N(CC)CC)=CC=C1C(C=1C=CC=CC=1)=C1C=CC(=[N+](CC)CC)C=C1 HXCILVUBKWANLN-UHFFFAOYSA-N 0.000 description 1
- 239000007853 buffer solution Substances 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 230000000711 cancerogenic effect Effects 0.000 description 1
- 239000003183 carcinogenic agent Substances 0.000 description 1
- 229940021722 caseins Drugs 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000001246 colloidal dispersion Methods 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 235000020247 cow milk Nutrition 0.000 description 1
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 description 1
- 235000018417 cysteine Nutrition 0.000 description 1
- 230000001687 destabilization Effects 0.000 description 1
- 235000021245 dietary protein Nutrition 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 238000005194 fractionation Methods 0.000 description 1
- 238000003505 heat denaturation Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 229940072221 immunoglobulins Drugs 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 150000002605 large molecules Chemical class 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 238000011020 pilot scale process Methods 0.000 description 1
- 235000008476 powdered milk Nutrition 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000005180 public health Effects 0.000 description 1
- 229940108461 rennet Drugs 0.000 description 1
- 108010058314 rennet Proteins 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 235000019515 salmon Nutrition 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 235000021246 κ-casein Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
- A23J1/20—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey
- A23J1/205—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey from whey, e.g. lactalbumine
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/14—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment
- A23C9/142—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration
- A23C9/1422—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration by ultrafiltration, microfiltration or diafiltration of milk, e.g. for separating protein and lactose; Treatment of the UF permeate
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C2210/00—Physical treatment of dairy products
- A23C2210/20—Treatment using membranes, including sterile filtration
- A23C2210/206—Membrane filtration of a permeate obtained by ultrafiltration, nanofiltration or microfiltration
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C2210/00—Physical treatment of dairy products
- A23C2210/20—Treatment using membranes, including sterile filtration
- A23C2210/208—Removal of bacteria by membrane filtration; Sterile filtration of milk products
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Water Supply & Treatment (AREA)
- Biochemistry (AREA)
- Peptides Or Proteins (AREA)
- Dairy Products (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US98918692A | 1992-12-11 | 1992-12-11 | |
US07/989,186 | 1992-12-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2151506A1 true CA2151506A1 (fr) | 1994-06-23 |
Family
ID=25534846
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA 2151506 Abandoned CA2151506A1 (fr) | 1992-12-11 | 1993-12-09 | Procede de production d'un concentre proteique de lactoserum non denature |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0673203A1 (fr) |
AU (1) | AU5557994A (fr) |
CA (1) | CA2151506A1 (fr) |
WO (1) | WO1994013148A1 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110663773A (zh) * | 2019-01-08 | 2020-01-10 | 东北农业大学 | 一种从鲜奶中分离天然乳清蛋白的方法及应用 |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUT77043A (hu) * | 1994-09-16 | 1998-03-02 | New Zealand Dairy Board | Kazein és savófehérjék fizikai elválasztása |
US5707678A (en) * | 1995-04-12 | 1998-01-13 | Galagen Inc. | Method for microfiltration of milk or colostral whey |
CA2165937A1 (fr) * | 1995-05-09 | 1996-11-10 | Immunotec Research Corporation Ltd. | Methode de preparation d'un concentre proteinique non caseique |
CA2197515A1 (fr) * | 1996-07-15 | 1998-01-16 | Reyad Mahmoud | Methodes pour traiter les produits laitiers |
DE69737030T2 (de) | 1996-09-06 | 2007-06-28 | Pall Corp. | Scherkraft trennverfahren und vorrichtung |
BR9915573B1 (pt) * | 1998-11-24 | 2010-11-30 | processo de preparação de uma formulação infantil predominantemente a base de uma matéria-prima de leite oriunda de soro do leite, em que a composição em aminoácidos é semelhante àquela do leite humano. | |
DK174656B1 (da) | 1999-06-04 | 2003-08-11 | Apv Pasilac As | Fremgangsmåde og anlæg til behandling af mælk |
NL1015851C2 (nl) * | 2000-08-01 | 2002-02-05 | Friesland Brands Bv | Werkwijze voor het filtreren van melk. |
LT5362B (lt) * | 2005-11-02 | 2006-10-25 | Vytautas Fedaravicius | KAZEINO GAMYBOS BuDAS IR IRENGINYS |
NL1033698C2 (nl) | 2007-04-16 | 2008-10-20 | Friesland Brands Bv | Functioneel serumeiwitproduct voor toepassing in kindervoeding en therapeutische samenstellingen, en werkwijzen ter bereiding daarvan. |
EP2280999B1 (fr) | 2008-05-15 | 2017-09-06 | Biosys Health Inc. | Processus de production de fractions de lait riches en immunoglobulines de sécrétion |
US9055752B2 (en) | 2008-11-06 | 2015-06-16 | Intercontinental Great Brands Llc | Shelf-stable concentrated dairy liquids and methods of forming thereof |
GB2469500B (en) | 2009-04-16 | 2012-06-06 | Cambridge Display Tech Ltd | Method of forming a polymer |
ES2852749T3 (es) | 2009-10-28 | 2021-09-14 | Valio Ltd | Producto de proteína del suero y método para su preparación |
UA112972C2 (uk) | 2010-09-08 | 2016-11-25 | Інтерконтінентал Грейт Брендс ЛЛС | Рідкий молочний концентрат з високим вмістом сухих речовин |
FI124323B (fi) | 2011-02-18 | 2014-06-30 | Valio Oy | Maitopohjainen tuote ja menetelmä sen valmistamiseksi |
NL2006662C2 (en) * | 2011-04-26 | 2012-10-29 | Friesland Brands Bv | Method of making a milk protein composition. |
US20140234487A1 (en) * | 2011-07-13 | 2014-08-21 | Friesland Brands B.V. | Dairy based compositions with low lps |
WO2013009185A1 (fr) * | 2011-07-13 | 2013-01-17 | Friesland Brands B.V. | Composition présentant digestibilité de protéines améliorée |
EP2548457A1 (fr) * | 2011-07-18 | 2013-01-23 | Ludwig-Maximilians-Universität München | Préparation de lait cru à utiliser pour empêcher ou traiter l'asthme et autres maladies allergiques chez les nourrissons et les enfants |
WO2013011040A1 (fr) * | 2011-07-18 | 2013-01-24 | Ludwig-Maximilians-Universität München | Préparation à base de lait cru pouvant être utilisée en vue de la prévention ou du traitement de l'asthme et d'autres affections allergiques chez le bébé et l'enfant |
WO2013137714A1 (fr) * | 2012-03-12 | 2013-09-19 | N.V. Nutricia | Procédé d'humanisation d'un lait écrémé d'animal et produits obtenus par ce procédé |
CA2808934C (fr) | 2012-04-10 | 2019-01-15 | Kraft Foods R&D, Inc. | Procede de production de fromage a la creme |
CN102630803A (zh) * | 2012-05-15 | 2012-08-15 | 东北农业大学 | 母乳化牛乳蛋白及其制备方法 |
JP6426108B2 (ja) * | 2013-01-23 | 2018-11-21 | アーラ フーズ エエムビエArla Foods amba | β−カゼイン組成物および関連製品を製造する方法 |
FI127870B (en) * | 2015-08-31 | 2019-04-15 | Valio Oy | Microparticulated ideal whey protein preparation, process for its preparation and its use |
CN109475164A (zh) * | 2016-05-12 | 2019-03-15 | 阿拉食品公司 | 促进脑发育的乳清制剂 |
EP3298903B1 (fr) | 2016-09-27 | 2020-11-18 | DMK Deutsches Milchkontor GmbH | Lait en poudre pauvre en germes avec haut index de protéines de lactosérum (iv) |
CN114144078B (zh) | 2019-07-23 | 2024-06-11 | 菲仕兰坎皮纳荷兰公司 | 包含乳脂肪和免疫球蛋白的营养组合物 |
CN112931677B (zh) * | 2021-03-09 | 2024-02-06 | 江南大学 | 一种高活性乳清蛋白及制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH576235A5 (en) * | 1973-08-20 | 1976-06-15 | Mueller Hans Maennedorf | Production of sterile milk protein - by multi-stage filtration |
US4112123A (en) * | 1976-07-21 | 1978-09-05 | Beatrice Foods Co. | Nutritionally balanced single food composition and method of production |
FR2631785A1 (fr) * | 1988-05-27 | 1989-12-01 | Agronomique Inst Nat Rech | Procede de fractionnement des proteines du lait humain, conduisant a la production, notamment de lactoferrine et d'(alpha)-lactalbumine, et produits obtenus |
FR2681218B1 (fr) * | 1991-09-16 | 1995-08-11 | Normandie Laitiere | Procede de traitement des laits permettant au moins de conserver leur aptitude fromagere. |
US5169666A (en) * | 1991-11-14 | 1992-12-08 | The United States Of America As Represented By The Secretary Of Agriculture | Preparation of simulated human milk protein by low temperature microfiltration |
-
1993
- 1993-12-09 WO PCT/CA1993/000518 patent/WO1994013148A1/fr not_active Application Discontinuation
- 1993-12-09 AU AU55579/94A patent/AU5557994A/en not_active Abandoned
- 1993-12-09 EP EP94900688A patent/EP0673203A1/fr not_active Ceased
- 1993-12-09 CA CA 2151506 patent/CA2151506A1/fr not_active Abandoned
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110663773A (zh) * | 2019-01-08 | 2020-01-10 | 东北农业大学 | 一种从鲜奶中分离天然乳清蛋白的方法及应用 |
Also Published As
Publication number | Publication date |
---|---|
AU5557994A (en) | 1994-07-04 |
WO1994013148A1 (fr) | 1994-06-23 |
EP0673203A1 (fr) | 1995-09-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Dead |