CA2149303A1 - Method of preparing .beta.-carbolines - Google Patents

Method of preparing .beta.-carbolines

Info

Publication number
CA2149303A1
CA2149303A1 CA002149303A CA2149303A CA2149303A1 CA 2149303 A1 CA2149303 A1 CA 2149303A1 CA 002149303 A CA002149303 A CA 002149303A CA 2149303 A CA2149303 A CA 2149303A CA 2149303 A1 CA2149303 A1 CA 2149303A1
Authority
CA
Canada
Prior art keywords
alkyl
halogen
alkoxy
carbolines
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002149303A
Other languages
English (en)
French (fr)
Inventor
Gregor Haffer
Klaus Nickisch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of CA2149303A1 publication Critical patent/CA2149303A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Non-Alcoholic Beverages (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
CA002149303A 1992-11-24 1993-11-22 Method of preparing .beta.-carbolines Abandoned CA2149303A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP4240672.2 1992-11-24
DE4240672A DE4240672A1 (de) 1992-11-24 1992-11-24 Neues Verfahren zur Herstellung von beta-Carbolinen

Publications (1)

Publication Number Publication Date
CA2149303A1 true CA2149303A1 (en) 1994-06-09

Family

ID=6474299

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002149303A Abandoned CA2149303A1 (en) 1992-11-24 1993-11-22 Method of preparing .beta.-carbolines

Country Status (10)

Country Link
US (1) US5569661A (https=)
EP (1) EP0670837B1 (https=)
JP (1) JPH08503224A (https=)
AT (1) ATE144259T1 (https=)
CA (1) CA2149303A1 (https=)
DE (2) DE4240672A1 (https=)
DK (1) DK0670837T3 (https=)
ES (1) ES2095148T3 (https=)
GR (1) GR3021686T3 (https=)
WO (1) WO1994012498A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5688807A (en) * 1994-03-11 1997-11-18 Eli Lilly And Company Method for treating 5HT2B receptor related conditions
KR101614723B1 (ko) 2008-01-11 2016-04-22 알바니 몰레큘라 리써치, 인크. Ｍｃｈ 길항물질로서 (1-아지논)-치환된 피리도인돌
US8618299B2 (en) * 2009-07-01 2013-12-31 Albany Molecular Research, Inc. Azinone-substituted azapolycycle MCH-1 antagonists, methods of making, and use thereof
JP2012532144A (ja) * 2009-07-01 2012-12-13 アルバニー モレキュラー リサーチ， インコーポレイテッド アジノン置換アゼピノ［ｂ］インドールおよびピリド−ピロロ−アゼピンｍｃｈ−１拮抗薬、ならびにその作製方法および使用
US9073925B2 (en) * 2009-07-01 2015-07-07 Albany Molecular Research, Inc. Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof
WO2011003007A1 (en) * 2009-07-01 2011-01-06 Albany Molecular Research, Inc. Azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine mch-1 antagonists, methods of making, and use thereof
US8993765B2 (en) 2010-12-21 2015-03-31 Albany Molecular Research, Inc. Tetrahydro-azacarboline MCH-1 antagonists, methods of making, and uses thereof
US8697700B2 (en) 2010-12-21 2014-04-15 Albany Molecular Research, Inc. Piperazinone-substituted tetrahydro-carboline MCH-1 antagonists, methods of making, and uses thereof
CN102558118B (zh) * 2011-12-28 2014-06-25 北京颖泰嘉和生物科技有限公司 一种制备4-甲基邻苯二甲酸酐的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3504045A1 (de) * 1985-02-04 1986-08-07 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur herstellung von ss-carbolinen durch dehydrierung
DE3540653A1 (de) * 1985-11-13 1987-05-14 Schering Ag Neue 3-oxadiazol- und 3-carbonsaeure-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
DE3608089A1 (de) * 1986-03-08 1987-09-10 Schering Ag Heteroaryl-oxy-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
DE4029389A1 (de) * 1990-09-13 1992-03-26 Schering Ag Verfahren zur herstellung von (beta)-carbolin-derivaten

Also Published As

Publication number Publication date
DK0670837T3 (https=) 1997-03-10
DE59304218D1 (de) 1996-11-21
DE4240672A1 (de) 1994-05-26
US5569661A (en) 1996-10-29
ES2095148T3 (es) 1997-02-01
JPH08503224A (ja) 1996-04-09
ATE144259T1 (de) 1996-11-15
EP0670837A1 (de) 1995-09-13
WO1994012498A1 (de) 1994-06-09
GR3021686T3 (en) 1997-02-28
EP0670837B1 (de) 1996-10-16

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Legal Events

Date Code Title Description
FZDE Discontinued