CA2146765A1 - Nouveaux derives du taxane, leur preparation et les compositions pharmaceutiques qui les contiennent - Google Patents

Nouveaux derives du taxane, leur preparation et les compositions pharmaceutiques qui les contiennent

Info

Publication number
CA2146765A1
CA2146765A1 CA002146765A CA2146765A CA2146765A1 CA 2146765 A1 CA2146765 A1 CA 2146765A1 CA 002146765 A CA002146765 A CA 002146765A CA 2146765 A CA2146765 A CA 2146765A CA 2146765 A1 CA2146765 A1 CA 2146765A1
Authority
CA
Canada
Prior art keywords
radical
carbon atoms
alkyl
general formula
radicals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002146765A
Other languages
English (en)
French (fr)
Inventor
Jean-Dominique Bourzat
Alain Commercon
Dominique Deprez
Jean-Pierre Pulicani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2146765A1 publication Critical patent/CA2146765A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/20—Processes
    • C25B3/25—Reduction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Electrochemistry (AREA)
  • Materials Engineering (AREA)
  • Metallurgy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA002146765A 1992-10-15 1993-10-13 Nouveaux derives du taxane, leur preparation et les compositions pharmaceutiques qui les contiennent Abandoned CA2146765A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9212331A FR2697019B1 (fr) 1992-10-15 1992-10-15 Nouveaux dérivés du taxane, leur préparation et les compositions pharmaceutiques qui les contiennent.
FR92/12331 1992-10-15
PCT/FR1993/001013 WO1994008984A1 (fr) 1992-10-15 1993-10-13 Nouveaux derives du taxane, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
CA2146765A1 true CA2146765A1 (fr) 1994-04-28

Family

ID=9434565

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002146765A Abandoned CA2146765A1 (fr) 1992-10-15 1993-10-13 Nouveaux derives du taxane, leur preparation et les compositions pharmaceutiques qui les contiennent

Country Status (15)

Country Link
EP (1) EP0664800A1 (cs)
JP (1) JPH08502280A (cs)
KR (1) KR950703551A (cs)
AU (1) AU5339594A (cs)
CA (1) CA2146765A1 (cs)
CZ (1) CZ95895A3 (cs)
FI (1) FI951789A7 (cs)
FR (1) FR2697019B1 (cs)
MX (1) MX9306227A (cs)
NO (1) NO951283D0 (cs)
PL (1) PL308361A1 (cs)
SK (1) SK49995A3 (cs)
TW (1) TW250480B (cs)
WO (1) WO1994008984A1 (cs)
ZA (1) ZA937558B (cs)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6011056A (en) 1991-09-23 2000-01-04 Florida State University C9 taxane derivatives and pharmaceutical compositions containing them
US6495704B1 (en) 1991-09-23 2002-12-17 Florida State University 9-desoxotaxanes and process for the preparation of 9-desoxotaxanes
US6794523B2 (en) 1991-09-23 2004-09-21 Florida State University Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them
US6710191B2 (en) 1993-03-05 2004-03-23 Florida State University 9β-hydroxytetracyclic taxanes
JP3892481B2 (ja) * 1993-03-05 2007-03-14 フロリダ・ステート・ユニバーシティー ９−デスオキソタキサンの製法
US5703247A (en) * 1993-03-11 1997-12-30 Virginia Tech Intellectual Properties, Inc. 2-Debenzoyl-2-acyl taxol derivatives and methods for making same
US5635531A (en) * 1996-07-08 1997-06-03 Bristol-Myers Squibb Company 3'-aminocarbonyloxy paclitaxels
US5773464A (en) * 1996-09-30 1998-06-30 Bristol-Myers Squibb Company C-10 epoxy taxanes
US5977386A (en) * 1996-12-24 1999-11-02 Bristol-Myers Squibb Company 6-thio-substituted paclitaxels
US5902822A (en) * 1997-02-28 1999-05-11 Bristol-Myers Squibb Company 7-methylthiooxomethyl and 7-methylthiodioxomethyl paclitaxels
US5912264A (en) * 1997-03-03 1999-06-15 Bristol-Myers Squibb Company 6-halo-or nitrate-substituted paclitaxels
US6017935A (en) * 1997-04-24 2000-01-25 Bristol-Myers Squibb Company 7-sulfur substituted paclitaxels
DE602004009943T2 (de) 2003-09-25 2008-08-28 Tapestry Pharmaceuticals, Inc., Boulder 9,10-alpha,alpha-oh-taxananaloga und verfahren zu deren herstellung
EP1894921A3 (en) * 2003-09-25 2008-03-12 Tapestry Pharmaceuticals, Inc. 9, 10-Alpha, Alpha-Oh-Taxane analogs and methods for production thereof
US11786504B2 (en) 2006-09-28 2023-10-17 Tapestry Pharmaceuticals, Inc. Taxane analogs for the treatment of brain cancer
WO2008106621A1 (en) 2007-02-28 2008-09-04 Tapestry Pharmaceuticals, Inc Taxane analogs for the treatment of brain cancer
WO2008121476A1 (en) 2007-03-28 2008-10-09 Tapestry Pharmaceuticals, Inc. Biologically active taxane analogs and methods of treatment by oral administration
US11873308B2 (en) 2006-11-06 2024-01-16 Tapestry Pharmaceuticals, Inc. Biologically active taxane analogs and methods of treatment by oral administration
JP5847942B2 (ja) 2012-07-19 2016-01-27 富士フイルム株式会社 タキサン系活性成分含有液体組成物、その製造方法及び液体製剤

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
US5059699A (en) * 1990-08-28 1991-10-22 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
MX9102128A (es) * 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene

Also Published As

Publication number Publication date
TW250480B (cs) 1995-07-01
MX9306227A (es) 1994-05-31
FI951789A0 (fi) 1995-04-13
JPH08502280A (ja) 1996-03-12
EP0664800A1 (fr) 1995-08-02
SK49995A3 (en) 1995-09-13
KR950703551A (ko) 1995-09-20
ZA937558B (en) 1994-05-04
NO951283L (no) 1995-04-03
FR2697019B1 (fr) 1994-11-25
WO1994008984A1 (fr) 1994-04-28
PL308361A1 (en) 1995-07-24
FI951789L (fi) 1995-04-13
NO951283D0 (no) 1995-04-03
AU5339594A (en) 1994-05-09
CZ95895A3 (en) 1995-09-13
FR2697019A1 (fr) 1994-04-22
FI951789A7 (fi) 1995-04-13

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Legal Events

Date Code Title Description
FZDE Discontinued