CA2134376C - Combinations of polymers for use in physiological tear compositions - Google Patents

Combinations of polymers for use in physiological tear compositions Download PDF

Info

Publication number
CA2134376C
CA2134376C CA002134376A CA2134376A CA2134376C CA 2134376 C CA2134376 C CA 2134376C CA 002134376 A CA002134376 A CA 002134376A CA 2134376 A CA2134376 A CA 2134376A CA 2134376 C CA2134376 C CA 2134376C
Authority
CA
Canada
Prior art keywords
composition
bicarbonate
concentration
mmol
calcium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002134376A
Other languages
English (en)
French (fr)
Other versions
CA2134376A1 (en
Inventor
Haresh G. Bhagat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Vision LLC
Original Assignee
Alcon Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Laboratories Inc filed Critical Alcon Laboratories Inc
Publication of CA2134376A1 publication Critical patent/CA2134376A1/en
Application granted granted Critical
Publication of CA2134376C publication Critical patent/CA2134376C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10—Carbonates; Bicarbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
CA002134376A 1993-12-20 1994-10-26 Combinations of polymers for use in physiological tear compositions Expired - Lifetime CA2134376C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17048293A 1993-12-20 1993-12-20
US170,482 1993-12-20

Publications (2)

Publication Number Publication Date
CA2134376A1 CA2134376A1 (en) 1995-06-21
CA2134376C true CA2134376C (en) 2001-10-23

Family

ID=22620024

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002134376A Expired - Lifetime CA2134376C (en) 1993-12-20 1994-10-26 Combinations of polymers for use in physiological tear compositions

Country Status (10)

Country Link
EP (1) EP0663208B1 (de)
JP (1) JPH07196474A (de)
KR (1) KR100307846B1 (de)
AT (1) ATE152348T1 (de)
AU (1) AU675371B2 (de)
CA (1) CA2134376C (de)
DE (1) DE69402951T2 (de)
DK (1) DK0663208T3 (de)
ES (1) ES2102175T3 (de)
GR (1) GR3023890T3 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6159483A (en) * 1998-06-01 2000-12-12 Colgate-Palmolive Company Stabilized liquid aqueous composition
TWI335819B (en) * 2002-12-24 2011-01-11 Alcon Inc Use of oculosurface selective glucocorticoid in the treatment of dry eye
TWI336257B (en) * 2003-06-13 2011-01-21 Alcon Inc Ophthalmic compositions containing a synergistic combination of three polymers
US7947295B2 (en) 2003-06-13 2011-05-24 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of two polymers
KR101147046B1 (ko) * 2003-06-13 2012-05-22 알콘, 인코퍼레이티드 시너지성의 2개의 폴리머 배합물을 포함하는 안과용 조성물
DK1654002T4 (da) * 2003-08-07 2014-02-17 Allergan Inc Sammensætninger til fremføring af terapeutiske midler til øjnene
US20050214382A1 (en) * 2004-03-29 2005-09-29 Erning Xia Zinc preservative composition and method of use
AU2008216497B2 (en) * 2007-02-09 2013-09-26 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of three polymers
JP6150510B2 (ja) * 2011-12-12 2017-06-21 ロート製薬株式会社 眼科用水性組成物
EP3470059B1 (de) 2015-01-26 2020-04-01 Bausch & Lomb Incorporated Ophthalmische suspensionszusammensetzung
TW202320815A (zh) * 2021-09-30 2023-06-01 日商樂敦製藥股份有限公司 眼科組成物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1263606A (en) * 1985-05-29 1989-12-05 Jeffrey P. Gilbard Non-toxic opthalmic preparations
JPS62122671A (ja) * 1985-11-23 1987-06-03 千寿製薬株式会社 眼内手術用高粘性液の製造法
EP0546728A3 (en) * 1991-12-13 1993-09-08 Alcon Laboratories Inc Physiological tear compositions and methods for their preparation

Also Published As

Publication number Publication date
KR950016762A (ko) 1995-07-20
JPH07196474A (ja) 1995-08-01
ATE152348T1 (de) 1997-05-15
EP0663208A3 (de) 1995-11-15
CA2134376A1 (en) 1995-06-21
GR3023890T3 (en) 1997-09-30
EP0663208A2 (de) 1995-07-19
DE69402951T2 (de) 1997-08-14
AU675371B2 (en) 1997-01-30
DK0663208T3 (da) 1997-10-13
ES2102175T3 (es) 1997-07-16
KR100307846B1 (ko) 2001-12-28
DE69402951D1 (de) 1997-06-05
EP0663208B1 (de) 1997-05-02
AU8160494A (en) 1995-06-29

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Effective date: 20141027