CA2134376C - Combinations of polymers for use in physiological tear compositions - Google Patents

Combinations of polymers for use in physiological tear compositions Download PDF

Info

Publication number
CA2134376C
CA2134376C CA002134376A CA2134376A CA2134376C CA 2134376 C CA2134376 C CA 2134376C CA 002134376 A CA002134376 A CA 002134376A CA 2134376 A CA2134376 A CA 2134376A CA 2134376 C CA2134376 C CA 2134376C
Authority
CA
Canada
Prior art keywords
composition
bicarbonate
concentration
mmol
calcium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002134376A
Other languages
English (en)
French (fr)
Other versions
CA2134376A1 (en
Inventor
Haresh G. Bhagat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Vision LLC
Original Assignee
Alcon Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Laboratories Inc filed Critical Alcon Laboratories Inc
Publication of CA2134376A1 publication Critical patent/CA2134376A1/en
Application granted granted Critical
Publication of CA2134376C publication Critical patent/CA2134376C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10—Carbonates; Bicarbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
CA002134376A 1993-12-20 1994-10-26 Combinations of polymers for use in physiological tear compositions Expired - Lifetime CA2134376C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17048293A 1993-12-20 1993-12-20
US170,482 1993-12-20

Publications (2)

Publication Number Publication Date
CA2134376A1 CA2134376A1 (en) 1995-06-21
CA2134376C true CA2134376C (en) 2001-10-23

Family

ID=22620024

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002134376A Expired - Lifetime CA2134376C (en) 1993-12-20 1994-10-26 Combinations of polymers for use in physiological tear compositions

Country Status (10)

Country Link
EP (1) EP0663208B1 (de)
JP (1) JPH07196474A (de)
KR (1) KR100307846B1 (de)
AT (1) ATE152348T1 (de)
AU (1) AU675371B2 (de)
CA (1) CA2134376C (de)
DE (1) DE69402951T2 (de)
DK (1) DK0663208T3 (de)
ES (1) ES2102175T3 (de)
GR (1) GR3023890T3 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6159483A (en) * 1998-06-01 2000-12-12 Colgate-Palmolive Company Stabilized liquid aqueous composition
UY28126A1 (es) * 2002-12-24 2004-06-30 Alcon Inc Uso de glucocorticoides selectivos para la superficie ocular en el tratamiento de la sequedad ocular
US7947295B2 (en) 2003-06-13 2011-05-24 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of two polymers
TWI336257B (en) * 2003-06-13 2011-01-21 Alcon Inc Ophthalmic compositions containing a synergistic combination of three polymers
JP4860475B2 (ja) * 2003-06-13 2012-01-25 アルコン，インコーポレイテッド ２種のポリマーの相乗作用的組み合わせを含む眼科用組成物
PL1654002T5 (pl) * 2003-08-07 2014-06-30 Allergan Inc Kompozycje do dostarczania środków terapeutycznych do oczu
US20050214382A1 (en) * 2004-03-29 2005-09-29 Erning Xia Zinc preservative composition and method of use
CA2675601C (en) * 2007-02-09 2016-06-21 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of three polymers
JP6150510B2 (ja) * 2011-12-12 2017-06-21 ロート製薬株式会社 眼科用水性組成物
WO2016123079A1 (en) 2015-01-26 2016-08-04 Bausch & Lomb Incorporated Ophthalmic suspension composition
TW202320815A (zh) * 2021-09-30 2023-06-01 日商樂敦製藥股份有限公司 眼科組成物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1263606A (en) * 1985-05-29 1989-12-05 Jeffrey P. Gilbard Non-toxic opthalmic preparations
JPS62122671A (ja) * 1985-11-23 1987-06-03 千寿製薬株式会社 眼内手術用高粘性液の製造法
EP0546728A3 (en) * 1991-12-13 1993-09-08 Alcon Laboratories Inc Physiological tear compositions and methods for their preparation

Also Published As

Publication number Publication date
EP0663208A3 (de) 1995-11-15
AU675371B2 (en) 1997-01-30
GR3023890T3 (en) 1997-09-30
JPH07196474A (ja) 1995-08-01
ES2102175T3 (es) 1997-07-16
AU8160494A (en) 1995-06-29
CA2134376A1 (en) 1995-06-21
ATE152348T1 (de) 1997-05-15
KR100307846B1 (ko) 2001-12-28
EP0663208A2 (de) 1995-07-19
EP0663208B1 (de) 1997-05-02
KR950016762A (ko) 1995-07-20
DE69402951T2 (de) 1997-08-14
DE69402951D1 (de) 1997-06-05
DK0663208T3 (da) 1997-10-13

Similar Documents

Publication Publication Date Title
US5460834A (en) Combinations of polymers for use in physiological tear compositions
US5403598A (en) Physiological tear compositions and methods for their preparation
US5597559A (en) Ophthalmic formulation
US4425344A (en) Compositions for the treatment of glaucoma containing triamterene
AU694497B2 (en) Ophthalmic composition with decreased viscosity
CA2839849C (en) Ophthalmic compositions containing a synergistic combination of two polymers
CA2134376C (en) Combinations of polymers for use in physiological tear compositions
CA2436269C (en) Artificial tear composition containing a combination of three demulcents
RU2157194C2 (ru) Офтальмическая композиция, содержащая ион-чувствительный, гидрофильный полимер и неорганическую соль при соотношении, которое дает низкую вязкость
WO1993017664A1 (en) Combinations of cellulosic polymers and carboxy vinyl polymers and their use in pharmaceutical compositions
US9636355B2 (en) Hypertonic dextran solution and methods of treating and preventing recurrent corneal erosion
JP2003190249A (ja) 洗眼用具
GB2169508A (en) Ophthalmic solutions containing hydroxyethyl cellulose
FI117921B (fi) Alennetun viskositeetin omaava oftalminen koostumus
GB2262448A (en) Aqueous formulations of sodium cromoglycate

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20141027