ES2102175T3 - Combinaciones de polimeros para su utilizacion en lagrimas artificiales. - Google Patents

Combinaciones de polimeros para su utilizacion en lagrimas artificiales.

Info

Publication number
ES2102175T3
ES2102175T3 ES94650039T ES94650039T ES2102175T3 ES 2102175 T3 ES2102175 T3 ES 2102175T3 ES 94650039 T ES94650039 T ES 94650039T ES 94650039 T ES94650039 T ES 94650039T ES 2102175 T3 ES2102175 T3 ES 2102175T3
Authority
ES
Spain
Prior art keywords
mmol
concentration
ions
polymers
combinations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94650039T
Other languages
English (en)
Inventor
Haresh G Bhagat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Vision LLC
Original Assignee
Alcon Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Laboratories Inc filed Critical Alcon Laboratories Inc
Application granted granted Critical
Publication of ES2102175T3 publication Critical patent/ES2102175T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10Carbonates; Bicarbonates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/30Zinc; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)

Abstract

SE DESCRIBEN UNAS COMPOSICIONES FISIOLOGICAS DE ARRANQUE PARA EL TRATAMIENTO DEL OJO QUE TIENEN UNA ALTA VISCOSIDAD Y CONTIENEN BICARBONATO, UN POLIMERO DE CELULOSA Y/O UN GLICOSAMINOGLICAN Y/O UN POLIMERO VINIL CARBOXI. UNA COMPOSICION RECLAMADA COMPRENDE: A) IONES DE POTASIO EN UNA CONCENTRACION ENTRE 11 Y UNOS 25 MMOL/L; B) IONES DE CALCIO EN UNA CONCENTRACION ENTRE 0.2 Y UNOS 0.5 MMOL/L; C) IONES DE MAGNESIO EN UNA CONCENTRACION ENTRE UNOS 0.15 Y UNOS 0.45 MMOL/L; D) IONES BICARBONATO EN UNA CONCENTRACION ENTRE UNOS 1 Y UNOS 36 MMOL/L; E) AL MENOS UN COMPONENTE DE UN GRUPO CONSISTENTE EN: I) UN POLIMERO DE CELULOSA; II) UN GLICOSAMINOGLICAN; III) UN POLIMERO VINIL CARBOXI; Y F) UNA VISCOSIDAD ENTRE UNOS 5 Y UNOS 10000 CENTIPOISES.
ES94650039T 1993-12-20 1994-12-19 Combinaciones de polimeros para su utilizacion en lagrimas artificiales. Expired - Lifetime ES2102175T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17048293A 1993-12-20 1993-12-20

Publications (1)

Publication Number Publication Date
ES2102175T3 true ES2102175T3 (es) 1997-07-16

Family

ID=22620024

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94650039T Expired - Lifetime ES2102175T3 (es) 1993-12-20 1994-12-19 Combinaciones de polimeros para su utilizacion en lagrimas artificiales.

Country Status (10)

Country Link
EP (1) EP0663208B1 (es)
JP (1) JPH07196474A (es)
KR (1) KR100307846B1 (es)
AT (1) ATE152348T1 (es)
AU (1) AU675371B2 (es)
CA (1) CA2134376C (es)
DE (1) DE69402951T2 (es)
DK (1) DK0663208T3 (es)
ES (1) ES2102175T3 (es)
GR (1) GR3023890T3 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6159483A (en) * 1998-06-01 2000-12-12 Colgate-Palmolive Company Stabilized liquid aqueous composition
TWI335819B (en) * 2002-12-24 2011-01-11 Alcon Inc Use of oculosurface selective glucocorticoid in the treatment of dry eye
CA2839847C (en) * 2003-06-13 2016-03-15 Masood A. Chowhan Ophthalmic compositions containing a synergistic combination of two polymers
US7947295B2 (en) 2003-06-13 2011-05-24 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of two polymers
TWI336257B (en) * 2003-06-13 2011-01-21 Alcon Inc Ophthalmic compositions containing a synergistic combination of three polymers
ATE444732T1 (de) * 2003-08-07 2009-10-15 Allergan Inc Zusammensetzungen zur abgabe von therapeutika in die augen und verfahren zu ihrer herstellung und verwendung
US20050214382A1 (en) * 2004-03-29 2005-09-29 Erning Xia Zinc preservative composition and method of use
AU2008216497B2 (en) 2007-02-09 2013-09-26 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of three polymers
JP6150510B2 (ja) * 2011-12-12 2017-06-21 ロート製薬株式会社 眼科用水性組成物
PT3721868T (pt) 2015-01-26 2022-08-12 Bausch & Lomb Composição para suspensão oftálmica
TW202320815A (zh) * 2021-09-30 2023-06-01 日商樂敦製藥股份有限公司 眼科組成物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1263606A (en) * 1985-05-29 1989-12-05 Jeffrey P. Gilbard Non-toxic opthalmic preparations
JPS62122671A (ja) * 1985-11-23 1987-06-03 千寿製薬株式会社 眼内手術用高粘性液の製造法
EP0546728A3 (en) * 1991-12-13 1993-09-08 Alcon Laboratories Inc Physiological tear compositions and methods for their preparation

Also Published As

Publication number Publication date
KR100307846B1 (ko) 2001-12-28
KR950016762A (ko) 1995-07-20
JPH07196474A (ja) 1995-08-01
GR3023890T3 (en) 1997-09-30
DE69402951T2 (de) 1997-08-14
ATE152348T1 (de) 1997-05-15
AU675371B2 (en) 1997-01-30
CA2134376C (en) 2001-10-23
EP0663208A2 (en) 1995-07-19
DE69402951D1 (de) 1997-06-05
EP0663208A3 (en) 1995-11-15
EP0663208B1 (en) 1997-05-02
DK0663208T3 (da) 1997-10-13
CA2134376A1 (en) 1995-06-21
AU8160494A (en) 1995-06-29

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