CA2113280A1 - Disease associated b-cell epitopes of tpo and use thereof - Google Patents

Disease associated b-cell epitopes of tpo and use thereof

Info

Publication number
CA2113280A1
CA2113280A1 CA002113280A CA2113280A CA2113280A1 CA 2113280 A1 CA2113280 A1 CA 2113280A1 CA 002113280 A CA002113280 A CA 002113280A CA 2113280 A CA2113280 A CA 2113280A CA 2113280 A1 CA2113280 A1 CA 2113280A1
Authority
CA
Canada
Prior art keywords
cells
antibody
human
tpo
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002113280A
Other languages
English (en)
French (fr)
Inventor
Basil Rapoport
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NICHOLS INSTITUTE DIAGNOSIS
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2113280A1 publication Critical patent/CA2113280A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0065Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4241Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA002113280A 1991-07-30 1992-07-30 Disease associated b-cell epitopes of tpo and use thereof Abandoned CA2113280A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73804091A 1991-07-30 1991-07-30
US07/738,040 1991-07-30

Publications (1)

Publication Number Publication Date
CA2113280A1 true CA2113280A1 (en) 1993-02-18

Family

ID=24966322

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002113280A Abandoned CA2113280A1 (en) 1991-07-30 1992-07-30 Disease associated b-cell epitopes of tpo and use thereof

Country Status (7)

Country Link
EP (1) EP0604453A4 (ja)
JP (1) JPH07503604A (ja)
AU (1) AU2403292A (ja)
CA (1) CA2113280A1 (ja)
FI (1) FI940391A (ja)
NO (1) NO940298D0 (ja)
WO (1) WO1993003146A1 (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0668918A1 (en) * 1991-08-28 1995-08-30 Institute Diagnostics Nichols Disease associated human autoantibodies specific for human thyroid peroxidase
CN105087512A (zh) * 2014-05-13 2015-11-25 苏州偲聚生物材料有限公司 可用于检测甲状腺疾病的蛋白质及该蛋白质的部分肽

Also Published As

Publication number Publication date
NO940298L (no) 1994-01-27
WO1993003146A1 (en) 1993-02-18
FI940391A0 (fi) 1994-01-26
EP0604453A4 (en) 1995-01-11
EP0604453A1 (en) 1994-07-06
FI940391A (fi) 1994-03-28
AU2403292A (en) 1993-03-02
NO940298D0 (no) 1994-01-27
JPH07503604A (ja) 1995-04-20

Similar Documents

Publication Publication Date Title
Medeiros-Neto et al. Inherited disorders of the thyroid system
Koch-Nolte et al. A new monoclonal antibody detects a developmentally regulated mouse ecto-ADP-ribosyltransferase on T cells: subset distribution, inbred strain variation, and modulation upon T cell activation
Kearse et al. Developmental regulation of alpha beta T cell antigen receptor expression results from differential stability of nascent TCR alpha proteins within the endoplasmic reticulum of immature and mature T cells.
JP2001522241A (ja) 診断方法および試薬
US5589358A (en) Ileal bile acid transporter compositions and methods
JP2002136292A (ja) 新規なレセプター型ホスホチロシンホスファターゼ
Kotani et al. A novel mutation in the human thyroid peroxidase gene resulting in a total iodide organification defect
IE904641A1 (en) Recombinant thyrotropin receptor
JPH0742320B2 (ja) 転移性ヒト腫瘍を確認する方法および組成物
FR2698880A1 (fr) Procédé de production de récepteurs T solubles, produits ainsi obtenus et leur utilisation dans des compositions diagnostiques ou thérapeutiques.
JPH09500020A (ja) レセプターキメラによる細胞性免疫の回復
JPH08510904A (ja) 新規な受容体型ホスホチロシンホスファターゼ−κ
EP0483281A1 (en) Recombinant human thyroid peroxidase
US6001360A (en) Method and compositions for early detection and treatment of insulin dependent diabetes mellitus
JPH05501952A (ja) Tsh受容体
US5538886A (en) Receptor-type phosphotyrosine phosphatase-alpha
US7196181B1 (en) Sequences encoding novel human thyroid peroxidase proteins and polypeptides
CA2113280A1 (en) Disease associated b-cell epitopes of tpo and use thereof
US5298407A (en) DNA encoding a protein active in lymphocyte-mediated cytotoxicity
US6627735B2 (en) Islet cell antigen 1851
US6747139B1 (en) Nucleic acid encoding human thyrotropin receptor
US5807714A (en) Method of production of antigen-specific glycosylation inhibiting factor
US6682905B1 (en) Receptor-type phosphotyrosine phosphatase-alpha
Mouse A New Monoclonal Antibody Detects
US20040142855A1 (en) Stem cell engraftment-enhancing cellular proteins and their uses

Legal Events

Date Code Title Description
FZDE Dead