EP0604453A4 - DISEASED B-CELL PITOPE OF TPO AND THEIR USE. - Google Patents
DISEASED B-CELL PITOPE OF TPO AND THEIR USE.Info
- Publication number
- EP0604453A4 EP0604453A4 EP92916802A EP92916802A EP0604453A4 EP 0604453 A4 EP0604453 A4 EP 0604453A4 EP 92916802 A EP92916802 A EP 92916802A EP 92916802 A EP92916802 A EP 92916802A EP 0604453 A4 EP0604453 A4 EP 0604453A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- tpo
- disease associated
- cell epitopes
- epitopes
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0065—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
- C07K16/4241—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US73804091A | 1991-07-30 | 1991-07-30 | |
US738040 | 1991-07-30 | ||
PCT/US1992/006283 WO1993003146A1 (en) | 1991-07-30 | 1992-07-30 | Disease associated b-cell epitopes of tpo and use thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0604453A1 EP0604453A1 (en) | 1994-07-06 |
EP0604453A4 true EP0604453A4 (en) | 1995-01-11 |
Family
ID=24966322
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP92916802A Withdrawn EP0604453A4 (en) | 1991-07-30 | 1992-07-30 | DISEASED B-CELL PITOPE OF TPO AND THEIR USE. |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0604453A4 (ja) |
JP (1) | JPH07503604A (ja) |
AU (1) | AU2403292A (ja) |
CA (1) | CA2113280A1 (ja) |
FI (1) | FI940391A (ja) |
NO (1) | NO940298D0 (ja) |
WO (1) | WO1993003146A1 (ja) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0668918A1 (en) * | 1991-08-28 | 1995-08-30 | Institute Diagnostics Nichols | Disease associated human autoantibodies specific for human thyroid peroxidase |
CN105087512A (zh) * | 2014-05-13 | 2015-11-25 | 苏州偲聚生物材料有限公司 | 可用于检测甲状腺疾病的蛋白质及该蛋白质的部分肽 |
-
1992
- 1992-07-30 JP JP5503701A patent/JPH07503604A/ja active Pending
- 1992-07-30 CA CA002113280A patent/CA2113280A1/en not_active Abandoned
- 1992-07-30 WO PCT/US1992/006283 patent/WO1993003146A1/en not_active Application Discontinuation
- 1992-07-30 AU AU24032/92A patent/AU2403292A/en not_active Abandoned
- 1992-07-30 EP EP92916802A patent/EP0604453A4/en not_active Withdrawn
-
1994
- 1994-01-26 FI FI940391A patent/FI940391A/fi not_active Application Discontinuation
- 1994-01-27 NO NO940298A patent/NO940298D0/no unknown
Non-Patent Citations (7)
Title |
---|
E. ZANELLI ET AL.: "Use of recombinant epitopes to study the heterogeneous nature of the autoantibodies against thyroid peroxidase in autoimmune thyroid disease", CLINICAL AND EXPERIMENTAL IMMUNOLOGY, vol. 87, no. 1, January 1992 (1992-01-01), pages 80 - 86 * |
F. LIBERT ET AL.: "Thyroperoxidase, but not the thyrotropin receptor, contains sequential epitopes recognized by autoantibodies inrecombinant peptides expressed in the pUEX vector", THE JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, vol. 73, no. 4, October 1991 (1991-10-01), pages 857 - 860 * |
M. LUDGATE ET AL.: "Antibodies to human thyroid peroxidase in autoimmune thyroid disease: studies with a cloned recombinant complementary deoxyribonucleic acid epitope", THE JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, vol. 68, no. 6, June 1989 (1989-06-01), pages 1091 - 1096 * |
R. ELISEI ET AL.: "Studies with recombinant autoepitopes of thyroid peroxidase: evidence suggesting an epitope shared between the thyroid and the gastric parietal cell", AUTOIMMUNITY, vol. 8, no. 1, 1990, pages 65 - 70 * |
R. FINKE ET AL.: "Determination at the molecular level of a B-cell epitope on thyroid peroxidase likely to be associated with autoimmune thyroid disease", CLINICAL ENDOCRINOLOGY & METABOLISM, vol. 73, no. 4, October 1991 (1991-10-01), pages 919 - 921 * |
REINHARD FINKE ET AL.: "Determination at the molecular level of a B-cell epitope on thyroid peroxidase", PROCEEDINGS OF THE INTERNATIONAL THYROID CONFERENCE, THE HAGUE, 4-8 FEBRUARY 1991. PROGRESS IN THYROID RESEARCH., February 1991 (1991-02-01), pages 437 - 439 * |
See also references of WO9303146A1 * |
Also Published As
Publication number | Publication date |
---|---|
AU2403292A (en) | 1993-03-02 |
WO1993003146A1 (en) | 1993-02-18 |
EP0604453A1 (en) | 1994-07-06 |
FI940391A0 (fi) | 1994-01-26 |
FI940391A (fi) | 1994-03-28 |
NO940298L (no) | 1994-01-27 |
CA2113280A1 (en) | 1993-02-18 |
NO940298D0 (no) | 1994-01-27 |
JPH07503604A (ja) | 1995-04-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19940228 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IT LI LU MC NL SE |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: NICHOLS INSTITUTE DIAGNOSTICS |
|
RHK1 | Main classification (correction) |
Ipc: C12N 15/53 |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 19941123 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IT LI LU MC NL SE |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 19960201 |