CA2100027C - Method of producing 5'-nucleotide - Google Patents

Method of producing 5'-nucleotide Download PDF

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Publication number
CA2100027C
CA2100027C CA002100027A CA2100027A CA2100027C CA 2100027 C CA2100027 C CA 2100027C CA 002100027 A CA002100027 A CA 002100027A CA 2100027 A CA2100027 A CA 2100027A CA 2100027 C CA2100027 C CA 2100027C
Authority
CA
Canada
Prior art keywords
nucleoside
phosphorylation
inosine
guanosine
temperature
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002100027A
Other languages
English (en)
French (fr)
Other versions
CA2100027A1 (en
Inventor
Akira Haze
Hiroyuki Hatano
Tomomi Ikemoto
Yoshifumi Kitamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kirin Food Tech Co Ltd
Original Assignee
Kirin Food Tech Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kirin Food Tech Co Ltd filed Critical Kirin Food Tech Co Ltd
Publication of CA2100027A1 publication Critical patent/CA2100027A1/en
Application granted granted Critical
Publication of CA2100027C publication Critical patent/CA2100027C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C07H19/207—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids the phosphoric or polyphosphoric acids being esterified by a further hydroxylic compound, e.g. flavine adenine dinucleotide or nicotinamide-adenine dinucleotide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA002100027A 1992-07-08 1993-07-07 Method of producing 5'-nucleotide Expired - Lifetime CA2100027C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP18114592 1992-07-08
JP181145/1992 1992-07-08

Publications (2)

Publication Number Publication Date
CA2100027A1 CA2100027A1 (en) 1994-01-09
CA2100027C true CA2100027C (en) 2003-10-07

Family

ID=16095679

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002100027A Expired - Lifetime CA2100027C (en) 1992-07-08 1993-07-07 Method of producing 5'-nucleotide

Country Status (7)

Country Link
US (1) US5623069A (en:Method)
KR (1) KR100270246B1 (en:Method)
CN (1) CN1033272C (en:Method)
CA (1) CA2100027C (en:Method)
ES (1) ES2055670B1 (en:Method)
IT (1) IT1264061B (en:Method)
TW (1) TW279165B (en:Method)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101665525B (zh) * 2009-09-10 2013-05-01 广东肇庆星湖生物科技股份有限公司 一种核苷酸的合成方法
CN101891772B (zh) * 2010-07-16 2012-11-28 广东肇庆星湖生物科技股份有限公司 一种5’-核苷酸二钠的制备方法
CN101914125A (zh) * 2010-08-12 2010-12-15 广东肇庆星湖生物科技股份有限公司 一种5’-鸟苷磷酸化反应液的萃取工艺
CN104151383A (zh) * 2014-07-15 2014-11-19 南通香地生物有限公司 尿苷酸二钠盐的生产方法
CN114315934A (zh) * 2021-12-22 2022-04-12 成都市海通药业有限公司 一种胞磷胆碱重要中间体胞苷酸的合成和精制方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1645896C3 (de) * 1965-03-17 1975-01-02 Ajinomoto Co., Inc., Tokio Verfahren zur Herstellung von 5'-Ribonucleotiden nd S'-Desoxyribonucleotiden
DE1620568A1 (de) * 1965-10-04 1970-08-27 Takeda Chemical Industries Ltd Verfahren zur Herstellung von Nucleotiden
US3433783A (en) * 1967-07-03 1969-03-18 Takeda Chemical Industries Ltd Method for the production of ribonucleoside-5'-phosphate
JPS5980694A (ja) * 1982-10-30 1984-05-10 Seikagaku Kogyo Co Ltd リン酸化合物の製造方法
JPS59163397A (ja) * 1983-03-09 1984-09-14 Seikagaku Kogyo Co Ltd リン酸化合物の製造方法
JPS59167599A (ja) * 1983-03-11 1984-09-21 Takeda Chem Ind Ltd イノシンおよびグアノシンの化学的リン酸化法
JP2671446B2 (ja) * 1988-10-25 1997-10-29 味の素株式会社 イノシン及びグアノシンの混合リン酸化方法

Also Published As

Publication number Publication date
IT1264061B (it) 1996-09-09
ES2055670A1 (es) 1994-08-16
ES2055670B1 (es) 1995-02-16
ITTO930501A0 (it) 1993-07-07
ITTO930501A1 (it) 1995-01-07
KR100270246B1 (ko) 2000-10-16
US5623069A (en) 1997-04-22
KR940005659A (ko) 1994-03-22
TW279165B (en:Method) 1996-06-21
CA2100027A1 (en) 1994-01-09
CN1033272C (zh) 1996-11-13
CN1086219A (zh) 1994-05-04

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