CA2077341C - Dentifrice inhibiting dental plaque - Google Patents
Dentifrice inhibiting dental plaque Download PDFInfo
- Publication number
- CA2077341C CA2077341C CA002077341A CA2077341A CA2077341C CA 2077341 C CA2077341 C CA 2077341C CA 002077341 A CA002077341 A CA 002077341A CA 2077341 A CA2077341 A CA 2077341A CA 2077341 C CA2077341 C CA 2077341C
- Authority
- CA
- Canada
- Prior art keywords
- silicone oil
- dentifrice
- antibacterial agent
- teeth
- plaque
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000551 dentifrice Substances 0.000 title claims abstract description 14
- 208000002064 Dental Plaque Diseases 0.000 title description 5
- 230000002401 inhibitory effect Effects 0.000 title description 2
- 229920002545 silicone oil Polymers 0.000 claims abstract description 32
- 239000003242 anti bacterial agent Substances 0.000 claims abstract description 19
- 239000003960 organic solvent Substances 0.000 claims abstract description 6
- 238000004090 dissolution Methods 0.000 claims abstract description 5
- 239000007788 liquid Substances 0.000 claims abstract description 5
- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical group OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 claims description 15
- 229960003500 triclosan Drugs 0.000 claims description 12
- 229920001296 polysiloxane Polymers 0.000 claims description 6
- 230000002421 anti-septic effect Effects 0.000 claims description 2
- 235000010290 biphenyl Nutrition 0.000 claims description 2
- 239000004305 biphenyl Substances 0.000 claims description 2
- 125000006267 biphenyl group Chemical group 0.000 claims description 2
- 150000002989 phenols Chemical class 0.000 claims description 2
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N phenylbenzene Natural products C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 claims description 2
- 230000007505 plaque formation Effects 0.000 abstract description 4
- 210000003296 saliva Anatomy 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 description 10
- 210000003298 dental enamel Anatomy 0.000 description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- -1 carboxylate salt Chemical class 0.000 description 4
- 239000004205 dimethyl polysiloxane Substances 0.000 description 4
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 4
- 239000011521 glass Substances 0.000 description 4
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 4
- 229930006000 Sucrose Natural products 0.000 description 3
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 208000002925 dental caries Diseases 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000010410 layer Substances 0.000 description 3
- 210000000214 mouth Anatomy 0.000 description 3
- 238000001179 sorption measurement Methods 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 239000005720 sucrose Substances 0.000 description 3
- 239000000606 toothpaste Substances 0.000 description 3
- DHXVGJBLRPWPCS-UHFFFAOYSA-N Tetrahydropyran Chemical compound C1CCOCC1 DHXVGJBLRPWPCS-UHFFFAOYSA-N 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 230000002209 hydrophobic effect Effects 0.000 description 2
- 230000005764 inhibitory process Effects 0.000 description 2
- 231100000252 nontoxic Toxicity 0.000 description 2
- 230000003000 nontoxic effect Effects 0.000 description 2
- 239000000523 sample Substances 0.000 description 2
- 238000010186 staining Methods 0.000 description 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 description 1
- 208000006558 Dental Calculus Diseases 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 241000521257 Hydrops Species 0.000 description 1
- 238000012404 In vitro experiment Methods 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 description 1
- 241001102009 Loxa Species 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 1
- 244000046052 Phaseolus vulgaris Species 0.000 description 1
- 208000014151 Stomatognathic disease Diseases 0.000 description 1
- 208000008312 Tooth Loss Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 239000004599 antimicrobial Substances 0.000 description 1
- 230000008275 binding mechanism Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 230000001055 chewing effect Effects 0.000 description 1
- 208000037976 chronic inflammation Diseases 0.000 description 1
- 230000006020 chronic inflammation Effects 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 230000005661 hydrophobic surface Effects 0.000 description 1
- 229910052588 hydroxylapatite Inorganic materials 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 125000004433 nitrogen atom Chemical group N* 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 125000005375 organosiloxane group Chemical group 0.000 description 1
- 238000010422 painting Methods 0.000 description 1
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 1
- 208000028169 periodontal disease Diseases 0.000 description 1
- 201000001245 periodontitis Diseases 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 125000001453 quaternary ammonium group Chemical group 0.000 description 1
- 229940071089 sarcosinate Drugs 0.000 description 1
- 229920006268 silicone film Polymers 0.000 description 1
- ZUFONQSOSYEWCN-UHFFFAOYSA-M sodium;2-(methylamino)acetate Chemical compound [Na+].CNCC([O-])=O ZUFONQSOSYEWCN-UHFFFAOYSA-M 0.000 description 1
- 239000002344 surface layer Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000011269 tar Substances 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 229940034610 toothpaste Drugs 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 108700012359 toxins Proteins 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Emergency Medicine (AREA)
- Cosmetics (AREA)
- Dental Preparations (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Earth Drilling (AREA)
- Medicinal Preparation (AREA)
- Electric Cable Installation (AREA)
- Laying Of Electric Cables Or Lines Outside (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Quick-Acting Or Multi-Walled Pipe Joints (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO901031 | 1990-03-05 | ||
| NO90901031A NO901031L (no) | 1990-03-05 | 1990-03-05 | Baktericid sammensetning. |
| PCT/NO1991/000032 WO1991013608A1 (en) | 1990-03-05 | 1991-03-04 | Dentifrice inhibiting dental plaque |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2077341A1 CA2077341A1 (en) | 1991-09-06 |
| CA2077341C true CA2077341C (en) | 2001-07-24 |
Family
ID=19892952
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002077341A Expired - Lifetime CA2077341C (en) | 1990-03-05 | 1991-03-04 | Dentifrice inhibiting dental plaque |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5422098A (enExample) |
| EP (1) | EP0518924B1 (enExample) |
| JP (1) | JPH05506846A (enExample) |
| KR (1) | KR0180243B1 (enExample) |
| AT (1) | ATE123216T1 (enExample) |
| AU (1) | AU646025B2 (enExample) |
| BR (1) | BR9106122A (enExample) |
| CA (1) | CA2077341C (enExample) |
| DE (1) | DE69110125T2 (enExample) |
| DK (1) | DK0518924T3 (enExample) |
| ES (1) | ES2075431T3 (enExample) |
| FI (1) | FI99259C (enExample) |
| GR (1) | GR3017204T3 (enExample) |
| HU (1) | HUT63052A (enExample) |
| NO (3) | NO901031L (enExample) |
| RU (1) | RU2071315C1 (enExample) |
| WO (1) | WO1991013608A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5188822A (en) * | 1991-08-07 | 1993-02-23 | Chesebrough-Pond's Usa Co., Division Of Conopco Inc. | Oral compositions containing an aminosilicone and a lipophilic compound |
| DE4341139C1 (de) * | 1993-12-02 | 1995-04-13 | Upmeyer Hans Juergen | Dimeticon zur Behandlung von Aphthen |
| US5888491A (en) * | 1993-12-06 | 1999-03-30 | Minnesota Mining And Manufacturing Company | Optionally crosslinkable coatings, compositions and methods of use |
| US6312668B2 (en) | 1993-12-06 | 2001-11-06 | 3M Innovative Properties Company | Optionally crosslinkable coatings, compositions and methods of use |
| US5662887A (en) * | 1994-12-01 | 1997-09-02 | Minnesota Mining And Manufacturing Company | Fluorocarbon containing coatings, compositions and methods of use |
| US5607663A (en) * | 1994-12-01 | 1997-03-04 | Minnesota Mining And Manufacturing Company | Hydrocarbyl containing coatings, compositions and methods of use |
| NO305815B1 (no) * | 1995-05-29 | 1999-07-26 | Abb Offshore Technology As | Neddykkbart verkt°y og verkt°ysystemer for sammenkopling av undersj°iske r°rledninger |
| CN1063610C (zh) * | 1996-02-06 | 2001-03-28 | 天津市医药工业技术研究所 | 广谱性杀菌制剂 |
| US6280707B1 (en) | 1998-12-15 | 2001-08-28 | Dentsply International Inc. | Oral prophalaxis paste |
| GB9901850D0 (en) * | 1998-06-27 | 1999-03-17 | Woolard Trevor | Killing microorganisms |
| GB2338651A (en) * | 1998-06-27 | 1999-12-29 | Woollard Trevor P | Liquid polymer composition |
| RU2145209C1 (ru) * | 1999-06-24 | 2000-02-10 | Открытое акционерное общество косметическое объединение "Свобода" | Лечебно-профилактическая зубная паста |
| GB9922871D0 (en) * | 1999-09-28 | 1999-12-01 | Mccormack Limited | A novel method for the temporary attenuation of dentine hypersensitivity |
| WO2002011682A2 (en) * | 2000-08-07 | 2002-02-14 | Unilever N.V. | Oral composition comprising a silicone and a water-insoluble active agent |
| US6685921B2 (en) | 2000-10-25 | 2004-02-03 | The Procter & Gamble Company | Dental care compositions |
| US7166235B2 (en) | 2002-05-09 | 2007-01-23 | The Procter & Gamble Company | Compositions comprising anionic functionalized polyorganosiloxanes for hydrophobically modifying surfaces and enhancing delivery of active agents to surfaces treated therewith |
| US7025950B2 (en) | 2002-05-09 | 2006-04-11 | The Procter & Gamble Company | Oral care compositions comprising dicarboxy functionalized polyorganosiloxanes |
| CN102802732B (zh) | 2009-09-11 | 2016-04-27 | 宝洁公司 | 用于口腔表面疏水改性的方法和组合物 |
| US8992893B2 (en) | 2011-04-19 | 2015-03-31 | Arms Pharmaceutical, Llc | Method of inhibiting harmful microorganisms and barrier-forming composition therefor |
| US10426761B2 (en) | 2011-04-19 | 2019-10-01 | Arms Pharmaceutical, Llc | Method for treatment of disease caused or aggravated by microorganisms or relieving symptoms thereof |
| MX355921B (es) | 2013-06-24 | 2018-05-03 | Procter & Gamble | Composicion para el cuidado bucal antimanchas. |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB686429A (en) * | 1951-01-09 | 1953-01-21 | Dow Corning Ltd | Improvements in or relating to dentifrices |
| GB789851A (en) * | 1952-10-08 | 1958-01-29 | Colgate Palmolive Co | Preparations for the care and hygiene of the mouth |
| US2806814A (en) * | 1954-10-04 | 1957-09-17 | Colgate Palmolive Co | Dental preparations |
| US3507955A (en) * | 1968-11-25 | 1970-04-21 | Prev Coat Corp | Silicone containing dentifrices |
| US4022880A (en) * | 1973-09-26 | 1977-05-10 | Lever Brothers Company | Anticalculus composition |
| US4202879A (en) * | 1977-07-18 | 1980-05-13 | The Procter & Gamble Company | Three phase antiperspirant stick |
| US4414200A (en) * | 1980-03-17 | 1983-11-08 | Kolmar Laboratories, Inc. | Powder stick composition for topical application |
| GB8411841D0 (en) * | 1984-05-09 | 1984-06-13 | Unilever Plc | Oral compositions |
| GB8526093D0 (en) * | 1985-10-22 | 1985-11-27 | Beecham Group Plc | Composition |
| ES2053963T3 (es) * | 1988-11-28 | 1994-08-01 | Unilever Nv | Dentifricos conteniendo amino alquil siliconas y tensoactivos de sarcosinato. |
| US5078988A (en) * | 1988-11-28 | 1992-01-07 | Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. | Dentrifrices including modified aminoalkyl silicones |
| DE68904539T2 (de) * | 1988-11-28 | 1993-06-03 | Unilever Nv | Zahnreinigungsmittel, die aminoalkylsilikone enthalten. |
| US5188822A (en) * | 1991-08-07 | 1993-02-23 | Chesebrough-Pond's Usa Co., Division Of Conopco Inc. | Oral compositions containing an aminosilicone and a lipophilic compound |
| US5254332A (en) * | 1992-03-20 | 1993-10-19 | Church & Dwight Co., Inc. | Low residue antiperspirant sticks |
-
1990
- 1990-03-05 NO NO90901031A patent/NO901031L/no unknown
-
1991
- 1991-03-04 KR KR1019920702136A patent/KR0180243B1/ko not_active Expired - Fee Related
- 1991-03-04 AT AT91905384T patent/ATE123216T1/de not_active IP Right Cessation
- 1991-03-04 DE DE69110125T patent/DE69110125T2/de not_active Expired - Lifetime
- 1991-03-04 DK DK91905384.3T patent/DK0518924T3/da active
- 1991-03-04 BR BR919106122A patent/BR9106122A/pt not_active Application Discontinuation
- 1991-03-04 JP JP91505211A patent/JPH05506846A/ja active Pending
- 1991-03-04 EP EP91905384A patent/EP0518924B1/en not_active Expired - Lifetime
- 1991-03-04 CA CA002077341A patent/CA2077341C/en not_active Expired - Lifetime
- 1991-03-04 HU HU922843A patent/HUT63052A/hu unknown
- 1991-03-04 WO PCT/NO1991/000032 patent/WO1991013608A1/en not_active Ceased
- 1991-03-04 ES ES91905384T patent/ES2075431T3/es not_active Expired - Lifetime
- 1991-03-04 US US07/930,551 patent/US5422098A/en not_active Expired - Fee Related
- 1991-03-04 AU AU73434/91A patent/AU646025B2/en not_active Expired
- 1991-03-04 RU SU915053128A patent/RU2071315C1/ru active
-
1992
- 1992-09-04 NO NO923471A patent/NO178652C/no not_active IP Right Cessation
- 1992-09-04 FI FI923982A patent/FI99259C/fi active
- 1992-11-12 NO NO924371A patent/NO176627C/no not_active IP Right Cessation
-
1995
- 1995-08-23 GR GR950402317T patent/GR3017204T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU646025B2 (en) | 1994-02-03 |
| FI99259B (fi) | 1997-10-15 |
| NO924371D0 (no) | 1992-11-12 |
| BR9106122A (pt) | 1993-03-09 |
| AU7343491A (en) | 1991-10-10 |
| NO901031D0 (no) | 1990-03-05 |
| DE69110125D1 (de) | 1995-07-06 |
| DE69110125T2 (de) | 1996-01-25 |
| EP0518924B1 (en) | 1995-05-31 |
| NO923471L (no) | 1992-09-04 |
| GR3017204T3 (en) | 1995-11-30 |
| ES2075431T3 (es) | 1995-10-01 |
| CA2077341A1 (en) | 1991-09-06 |
| HUT63052A (en) | 1993-07-28 |
| FI923982A0 (fi) | 1992-09-04 |
| WO1991013608A1 (en) | 1991-09-19 |
| EP0518924A1 (en) | 1992-12-23 |
| NO178652C (no) | 1996-05-08 |
| NO901031L (no) | 1991-09-06 |
| NO923471D0 (no) | 1992-09-04 |
| JPH05506846A (ja) | 1993-10-07 |
| US5422098A (en) | 1995-06-06 |
| FI923982L (fi) | 1992-09-04 |
| KR0180243B1 (ko) | 1999-03-20 |
| FI99259C (fi) | 1998-01-26 |
| RU2071315C1 (ru) | 1997-01-10 |
| NO176627C (no) | 1999-11-11 |
| HU9202843D0 (en) | 1992-11-30 |
| NO924371L (enExample) | 1994-05-13 |
| NO178652B (no) | 1996-01-29 |
| ATE123216T1 (de) | 1995-06-15 |
| DK0518924T3 (da) | 1995-10-09 |
| NO176627B (no) | 1995-01-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKEX | Expiry |