CA2073050A1 - Use of complexes of radioactive metal ions with all-cis-1,3,5-triamino-2,4, 6-cyclohexanetriol and its derivatives for radiodiagnostic purposes and in tumor therapy and for the preparation of agents for radiodiagnost c purposes and for tumor therapy - Google Patents

Use of complexes of radioactive metal ions with all-cis-1,3,5-triamino-2,4, 6-cyclohexanetriol and its derivatives for radiodiagnostic purposes and in tumor therapy and for the preparation of agents for radiodiagnost c purposes and for tumor therapy

Info

Publication number
CA2073050A1
CA2073050A1 CA002073050A CA2073050A CA2073050A1 CA 2073050 A1 CA2073050 A1 CA 2073050A1 CA 002073050 A CA002073050 A CA 002073050A CA 2073050 A CA2073050 A CA 2073050A CA 2073050 A1 CA2073050 A1 CA 2073050A1
Authority
CA
Canada
Prior art keywords
complexes
alkyl groups
use according
radiodiagnostic
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002073050A
Other languages
English (en)
French (fr)
Inventor
Isidor Erni
Hans Heggetschweiler
Walter Schneider
Peter Geisser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vifor International AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2073050A1 publication Critical patent/CA2073050A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA002073050A 1990-09-05 1991-09-05 Use of complexes of radioactive metal ions with all-cis-1,3,5-triamino-2,4, 6-cyclohexanetriol and its derivatives for radiodiagnostic purposes and in tumor therapy and for the preparation of agents for radiodiagnost c purposes and for tumor therapy Abandoned CA2073050A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP4028139.6 1990-09-05
DE4028139A DE4028139A1 (de) 1990-09-05 1990-09-05 Verwendung der komplexe radioaktiver metallionen mit all-cis-1,3,5-triamino-2,4,6-cyclohexantriol und seinen derivaten fuer roentgendiagnostische zwecke und in der tumortherapie sowie zur herstellung von mitteln fuer roentgendiagnostische zwecke und fuer die tumortherapie

Publications (1)

Publication Number Publication Date
CA2073050A1 true CA2073050A1 (en) 1992-03-06

Family

ID=6413642

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002073050A Abandoned CA2073050A1 (en) 1990-09-05 1991-09-05 Use of complexes of radioactive metal ions with all-cis-1,3,5-triamino-2,4, 6-cyclohexanetriol and its derivatives for radiodiagnostic purposes and in tumor therapy and for the preparation of agents for radiodiagnost c purposes and for tumor therapy

Country Status (10)

Country Link
EP (1) EP0504339A1 (pt)
JP (1) JPH05502456A (pt)
KR (1) KR920702235A (pt)
AU (1) AU658148B2 (pt)
CA (1) CA2073050A1 (pt)
DE (1) DE4028139A1 (pt)
MX (1) MX9100967A (pt)
PT (1) PT98869A (pt)
TW (1) TW197951B (pt)
WO (1) WO1992004056A1 (pt)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104321082A (zh) * 2012-05-18 2015-01-28 拜耳医药股份有限公司 用于x射线成像的双氮杂肌醇重金属络合物

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5830430A (en) 1995-02-21 1998-11-03 Imarx Pharmaceutical Corp. Cationic lipids and the use thereof
EP2796152A1 (en) 2013-04-25 2014-10-29 Bayer Pharma Aktiengesellschaft Unsymmetrical Bis Azainositol Hafnium Complexes for X-Ray Imaging
EP2873670A1 (en) 2013-11-14 2015-05-20 Bayer Pharma Aktiengesellschaft Bis azainositol zirconium complexes for X-ray imaging

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3503614A1 (de) * 1985-02-02 1986-08-07 Laboratorien Hausmann AG, St. Gallen All-cis-1,3,5-triamino-2,4,6-cyclohexantriol-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate
GB8900719D0 (en) * 1989-01-13 1989-03-08 Nycomed As Compounds
CH679742A5 (pt) * 1990-01-09 1992-04-15 Byk Gulden Lomberg Chem Fab

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104321082A (zh) * 2012-05-18 2015-01-28 拜耳医药股份有限公司 用于x射线成像的双氮杂肌醇重金属络合物

Also Published As

Publication number Publication date
AU8436791A (en) 1992-03-30
TW197951B (pt) 1993-01-11
WO1992004056A1 (de) 1992-03-19
PT98869A (pt) 1992-07-31
KR920702235A (ko) 1992-09-03
DE4028139A1 (de) 1992-03-12
JPH05502456A (ja) 1993-04-28
EP0504339A1 (de) 1992-09-23
MX9100967A (es) 1992-05-04
AU658148B2 (en) 1995-04-06

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