CA2064878A1 - Proteine specifique des os - Google Patents
Proteine specifique des osInfo
- Publication number
- CA2064878A1 CA2064878A1 CA 2064878 CA2064878A CA2064878A1 CA 2064878 A1 CA2064878 A1 CA 2064878A1 CA 2064878 CA2064878 CA 2064878 CA 2064878 A CA2064878 A CA 2064878A CA 2064878 A1 CA2064878 A1 CA 2064878A1
- Authority
- CA
- Canada
- Prior art keywords
- protein
- ile
- sequence
- polypeptide
- thr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39777989A | 1989-08-21 | 1989-08-21 | |
US397,779 | 1989-08-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2064878A1 true CA2064878A1 (fr) | 1991-02-22 |
Family
ID=23572594
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA 2064878 Abandoned CA2064878A1 (fr) | 1989-08-21 | 1990-08-21 | Proteine specifique des os |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0489062A4 (fr) |
JP (1) | JPH05500503A (fr) |
AU (1) | AU632160B2 (fr) |
CA (1) | CA2064878A1 (fr) |
WO (1) | WO1991002744A1 (fr) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6150328A (en) | 1986-07-01 | 2000-11-21 | Genetics Institute, Inc. | BMP products |
US5187076A (en) * | 1986-07-01 | 1993-02-16 | Genetics Institute, Inc. | DNA sequences encoding BMP-6 proteins |
US5366875A (en) * | 1986-07-01 | 1994-11-22 | Genetics Institute, Inc. | Methods for producing BMP-7 proteins |
US6432919B1 (en) | 1986-07-01 | 2002-08-13 | Genetics Institute, Inc. | Bone morphogenetic protein-3 and compositions |
US5459047A (en) * | 1986-07-01 | 1995-10-17 | Genetics Institute, Inc. | BMP-6 proteins |
US5013649A (en) * | 1986-07-01 | 1991-05-07 | Genetics Institute, Inc. | DNA sequences encoding osteoinductive products |
US5543394A (en) * | 1986-07-01 | 1996-08-06 | Genetics Institute, Inc. | Bone morphogenetic protein 5(BMP-5) compositions |
US5939388A (en) * | 1986-07-01 | 1999-08-17 | Rosen; Vicki A. | Methods of administering BMP-5 compositions |
US5324819A (en) * | 1988-04-08 | 1994-06-28 | Stryker Corporation | Osteogenic proteins |
US5670336A (en) * | 1988-04-08 | 1997-09-23 | Stryker Corporation | Method for recombinant production of osteogenic protein |
EP1225225A3 (fr) * | 1988-04-08 | 2003-01-08 | Stryker Corporation | Dispositifs ostéogéniques |
US6586388B2 (en) | 1988-04-08 | 2003-07-01 | Stryker Corporation | Method of using recombinant osteogenic protein to repair bone or cartilage defects |
US5258494A (en) | 1988-04-08 | 1993-11-02 | Stryker Corporation | Osteogenic proteins |
US5284756A (en) * | 1988-10-11 | 1994-02-08 | Lynn Grinna | Heterodimeric osteogenic factor |
US7378392B1 (en) | 1990-05-16 | 2008-05-27 | Genetics Institute, Llc | Bone and cartilage inductive proteins |
US5688678A (en) * | 1990-05-16 | 1997-11-18 | Genetics Institute, Inc. | DNA encoding and methods for producing BMP-8 proteins |
US5707810A (en) * | 1991-03-11 | 1998-01-13 | Creative Biomolecules, Inc. | Method of diagnosing renal tissue damage or disease |
US5650276A (en) * | 1991-03-11 | 1997-07-22 | Creative Biomolecules, Inc. | Morphogenic protein screening method |
US6287816B1 (en) | 1991-06-25 | 2001-09-11 | Genetics Institute, Inc. | BMP-9 compositions |
DK0592562T3 (da) * | 1991-06-25 | 1999-08-30 | Genetics Inst | BMP-9-præparater |
CA2116560C (fr) * | 1991-08-30 | 2002-01-08 | Charles M. Cohen | Methode de criblage de proteines morphogeniques |
JP3504263B2 (ja) | 1991-11-04 | 2004-03-08 | ジェネティックス・インスチチュート・リミテッド・ライアビリティ・カンパニー | 組み換え型骨形態形成蛋白ヘテロダイマー、組成物および使用法 |
US6492508B1 (en) | 1996-06-03 | 2002-12-10 | United States Surgical Corp. A Division Of Tyco Healthcare Group | Nucleic acids encoding extracellular matrix proteins |
US5928940A (en) * | 1996-09-24 | 1999-07-27 | Creative Biomolecules, Inc. | Morphogen-responsive signal transducer and methods of use thereof |
US6034062A (en) * | 1997-03-13 | 2000-03-07 | Genetics Institute, Inc. | Bone morphogenetic protein (BMP)-9 compositions and their uses |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4294753A (en) * | 1980-08-04 | 1981-10-13 | The Regents Of The University Of California | Bone morphogenetic protein process |
US4455256A (en) * | 1981-05-05 | 1984-06-19 | The Regents Of The University Of California | Bone morphogenetic protein |
US4789732A (en) * | 1980-08-04 | 1988-12-06 | Regents Of The University Of California | Bone morphogenetic protein composition |
US4434094A (en) * | 1983-04-12 | 1984-02-28 | Collagen Corporation | Partially purified osteogenic factor and process for preparing same from demineralized bone |
CA1229789A (fr) * | 1983-06-06 | 1987-12-01 | David Baylink | Polypeptides stimulant la croissance du tissu osseaux |
US4795804A (en) * | 1983-08-16 | 1989-01-03 | The Regents Of The University Of California | Bone morphogenetic agents |
US4608199A (en) * | 1984-03-20 | 1986-08-26 | Arnold Caplan | Bone protein purification process |
US4627982A (en) * | 1984-07-16 | 1986-12-09 | Collagen Corporation | Partially purified bone-inducing factor |
DE3588058T3 (de) * | 1984-07-16 | 2005-04-07 | Celtrix Pharmaceuticals, Inc., Palo Alto | Knorpel-induzierende Polypeptid-Faktoren aus Knochen |
IL83003A (en) * | 1986-07-01 | 1995-07-31 | Genetics Inst | Factors that soak bone formation |
US4816442A (en) * | 1986-11-07 | 1989-03-28 | Collagen Corporation | Method of inhibiting tumor growth sensitive to CIF-βtreatment |
WO1989009605A1 (fr) * | 1988-04-06 | 1989-10-19 | Collagen Corporation | Proteine osteogene |
-
1990
- 1990-08-21 CA CA 2064878 patent/CA2064878A1/fr not_active Abandoned
- 1990-08-21 EP EP19900912603 patent/EP0489062A4/en not_active Withdrawn
- 1990-08-21 JP JP51192890A patent/JPH05500503A/ja active Pending
- 1990-08-21 AU AU61870/90A patent/AU632160B2/en not_active Ceased
- 1990-08-21 WO PCT/US1990/004745 patent/WO1991002744A1/fr not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JPH05500503A (ja) | 1993-02-04 |
WO1991002744A1 (fr) | 1991-03-07 |
EP0489062A1 (fr) | 1992-06-10 |
EP0489062A4 (en) | 1992-08-12 |
AU6187090A (en) | 1991-04-03 |
AU632160B2 (en) | 1992-12-17 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU632160B2 (en) | Bone-specific protein | |
EP0336760A2 (fr) | Protéines induisant la croissance des os | |
US6190884B1 (en) | Connective tissue growth factor | |
JP2665359B2 (ja) | 免疫親和性による精製方法 | |
US6656708B1 (en) | Human growth differentiation factor encoding sequence and polypeptide encoded by such DNA sequence and producing method thereof | |
JP3192651B2 (ja) | インターロイキン―1インヒビター | |
US5731167A (en) | Autotaxin: motility stimulating protein useful in cancer diagnosis and therapy | |
US5136025A (en) | Method to purify basic fibroblast growth factor | |
CA2017466A1 (fr) | Facteur de calcification des os | |
JP2771220B2 (ja) | 植物性リボソーム不活化タンパク質をコードするヌクレオチド配列 | |
EP0377855B1 (fr) | Facteur de croissance des cellules endothéliales | |
CA2128215C (fr) | L'autotaxine, proteine stimulant la motilite qui est utile dans le diagnostic et le traitement du cancer | |
EP0241830A2 (fr) | Facteur de croissance, dérivé d'hépatomes | |
US7939635B2 (en) | Autotaxin: motility stimulating protein useful in cancer diagnosis and therapy | |
JP3057292B2 (ja) | モノクローナル抗体、ハイブリドーマ、それらの製造法および用途 | |
EP0506377B1 (fr) | Protéine liant le calmodulin | |
CA2026122A1 (fr) | Anticorps monoclonaux contre une proteine fgf acide, sa production et son utilisation | |
US5635374A (en) | Bone calcification factor and recombinant production of the factor nucleic acid encoding | |
JP3232415B2 (ja) | モノクローナル抗体,その製造法および用途 | |
JPH09500265A (ja) | キセノニンとしてデザインされたペプチドファミリー | |
JPH05509320A (ja) | 組織誘導型腫瘍成長抑制物質、その調製及び使用方法 | |
JPS63119679A (ja) | インヒビンのα鎖またはβ鎖をコ−ドしている核酸、並びにその様な核酸を用いてポリペプチドを合成する方法 | |
US5817501A (en) | DNA encoding suppressin protein and uses thereof | |
JP3024987B2 (ja) | 抗体、その製造法および用途 | |
JP2713871B2 (ja) | ヒトインヒビンβ▲A▼鎖の合成方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Dead |