CA2056445A1 - Injectable clarithromycin composition - Google Patents

Injectable clarithromycin composition

Info

Publication number
CA2056445A1
CA2056445A1 CA002056445A CA2056445A CA2056445A1 CA 2056445 A1 CA2056445 A1 CA 2056445A1 CA 002056445 A CA002056445 A CA 002056445A CA 2056445 A CA2056445 A CA 2056445A CA 2056445 A1 CA2056445 A1 CA 2056445A1
Authority
CA
Canada
Prior art keywords
composition
clarithromycin
oil
acid
stabilizing agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002056445A
Other languages
English (en)
French (fr)
Inventor
Ho-Wah Hui
Chung-Chiang Hsu
John B. Cannon
Michael W. Lovell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2056445A1 publication Critical patent/CA2056445A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10C—WORKING-UP PITCH, ASPHALT, BITUMEN, TAR; PYROLIGNEOUS ACID
    • C10C3/00—Working-up pitch, asphalt, bitumen
    • C10C3/002—Working-up pitch, asphalt, bitumen by thermal means
    • C—CHEMISTRY; METALLURGY
    • C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10C—WORKING-UP PITCH, ASPHALT, BITUMEN, TAR; PYROLIGNEOUS ACID
    • C10C3/00—Working-up pitch, asphalt, bitumen
    • C10C3/06—Working-up pitch, asphalt, bitumen by distillation
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F9/00—Artificial filaments or the like of other substances; Manufacture thereof; Apparatus specially adapted for the manufacture of carbon filaments
    • D01F9/08—Artificial filaments or the like of other substances; Manufacture thereof; Apparatus specially adapted for the manufacture of carbon filaments of inorganic material
    • D01F9/12—Carbon filaments; Apparatus specially adapted for the manufacture thereof
    • D01F9/14—Carbon filaments; Apparatus specially adapted for the manufacture thereof by decomposition of organic filaments
    • D01F9/145—Carbon filaments; Apparatus specially adapted for the manufacture thereof by decomposition of organic filaments from pitch or distillation residues
    • D01F9/155—Carbon filaments; Apparatus specially adapted for the manufacture thereof by decomposition of organic filaments from pitch or distillation residues from petroleum pitch

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Materials Engineering (AREA)
  • Structural Engineering (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Civil Engineering (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Textile Engineering (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA002056445A 1989-05-26 1990-05-25 Injectable clarithromycin composition Abandoned CA2056445A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35828389A 1989-05-26 1989-05-26
US358,283 1989-05-26
PCT/US1990/003063 WO1990014094A1 (en) 1989-05-26 1990-05-25 Injectable clarithromycin composition

Publications (1)

Publication Number Publication Date
CA2056445A1 true CA2056445A1 (en) 1990-11-27

Family

ID=23409043

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002056445A Abandoned CA2056445A1 (en) 1989-05-26 1990-05-25 Injectable clarithromycin composition

Country Status (9)

Country Link
EP (1) EP0473707A4 (el)
JP (1) JP2963537B2 (el)
KR (1) KR920700655A (el)
AU (1) AU630469B2 (el)
CA (1) CA2056445A1 (el)
GR (1) GR1002177B (el)
IL (1) IL94516A (el)
NZ (1) NZ233827A (el)
WO (1) WO1990014094A1 (el)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4447972B4 (de) * 1993-05-27 2007-12-27 Novartis Ag Galenische Formulierungen
GB2278780B (en) * 1993-05-27 1998-10-14 Sandoz Ltd Macrolide formulations
CH686761A5 (de) * 1993-05-27 1996-06-28 Sandoz Ag Galenische Formulierungen.
DE4410637C1 (de) * 1994-03-26 1995-09-21 Boehringer Ingelheim Vetmed Injizierbare Lösungen von Dirithromycin
US5795871A (en) * 1994-04-26 1998-08-18 Nobuhiro Narita Pharmaceutical composition for treatment of non-small cell lung cancer
US5726181A (en) * 1995-06-05 1998-03-10 Bionumerik Pharmaceuticals, Inc. Formulations and compositions of poorly water soluble camptothecin derivatives
US6017948A (en) * 1998-10-30 2000-01-25 Supergen, Inc. Water-miscible pharmaceutical compositions
US6946137B2 (en) * 2001-10-19 2005-09-20 Idexx Laboratories, Inc. Methods for the controlled delivery of pharmacologically active compounds
AU2002347541A1 (en) * 2001-12-13 2003-06-23 Ranbaxy Laboratories Limited Stable topical formulation of clarithromycin
US20050049209A1 (en) * 2003-08-06 2005-03-03 Chen Andrew Xian Pharmaceutical compositions for delivering macrolides
US7871632B2 (en) 2004-07-12 2011-01-18 Adventrx Pharmaceuticals, Inc. Compositions for delivering highly water soluble drugs
US8268876B2 (en) 2006-03-08 2012-09-18 Nihon Nohyaku Co., Ltd. Pharmaceutical composition for external use
MX2008011435A (es) 2006-03-08 2009-02-03 Nihon Nohyaku Co Ltd Composicion farmaceutica para uso externo.
US20100173965A1 (en) 2007-09-05 2010-07-08 Pola Pharma Inc. Antifungal composition
CN101808639B (zh) 2007-09-05 2012-12-05 宝丽制药股份有限公司 抗真菌医药组合物
US20100204293A1 (en) 2007-09-05 2010-08-12 Pola Pharma Inc. Pharmaceutical composition
EP2416758B8 (en) 2009-04-09 2017-10-18 Pola Pharma Inc. Antimycotic pharmaceutical composition
CN102387785B (zh) 2009-04-09 2017-08-25 宝丽制药股份有限公司 抗真菌药物组合物
KR101754697B1 (ko) 2009-08-25 2017-07-06 가부시키가이샤 폴라 파마 항진균성 약제학적 조성물
RU2707748C2 (ru) 2013-11-08 2019-11-29 Активус Фарма Ко., Лтд. Композиция водной суспензии, включающая наночастицы макролидных антибиотиков
CN116650492A (zh) * 2017-04-03 2023-08-29 消化系统疾病中心 用于治疗链球菌感染以治疗牛皮癣的抗生素化合物的施用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61291520A (ja) * 1985-06-19 1986-12-22 Daigo Eiyou Kagaku Kk エリスロマイシン脂肪乳剤
IL87219A0 (en) * 1987-08-07 1988-12-30 Abbott Lab Erythromycin formulations for oral administration
CA1337397C (en) * 1988-09-29 1995-10-24 Hideo Nakajima Emulsified composition

Also Published As

Publication number Publication date
KR920700655A (ko) 1992-08-10
GR1002177B (en) 1996-03-07
EP0473707A4 (en) 1992-12-09
NZ233827A (en) 1991-06-25
JPH04505762A (ja) 1992-10-08
AU5811090A (en) 1990-12-18
WO1990014094A1 (en) 1990-11-29
AU630469B2 (en) 1992-10-29
EP0473707A1 (en) 1992-03-11
IL94516A0 (en) 1991-03-10
JP2963537B2 (ja) 1999-10-18
GR900100402A (el) 1991-10-10
IL94516A (en) 1994-12-29

Similar Documents

Publication Publication Date Title
AU630469B2 (en) Injectable clarithromycin composition
EP0215313B1 (en) Emulsion compositions for the parenteral and/or oral administration of sparingly water soluble ionizable hydrophobic drugs
US5085864A (en) Injectable formulation for lipophilic drugs
EP0327280B1 (en) Cyclosporin compositions
US5474979A (en) Nonirritating emulsions for sensitive tissue
NO844144L (no) Legemiddeltilberedning
JPH0647533B2 (ja) ４−ビフエニリル酢酸系化合物含有脂肪乳剤
US4849451A (en) Fat emulsion containing prostaglandin
US20080132582A1 (en) Propofol formulation containing reduced oil and surfactants
US20050049209A1 (en) Pharmaceutical compositions for delivering macrolides
EP0257454A1 (en) Oil-in-water type fat emulsion of 1-[2-(2,4-dichlorophenyl)-3-methyl-1-pentenyl]-1H-imidazole
EP0426029A1 (en) Injectable formulation for lipophilic drugs
JP2939082B2 (ja) 安定なビタミンａパルミテート及びビタミンｅ類可溶化点眼剤
EP0418004B1 (en) Preventive and therapeutic agent for hepatitis
JP3132085B2 (ja) 脂肪乳剤
EP0350864B1 (en) Aqueous solution containing fat-soluble vitamin k
JP2004525169A (ja) 医薬組成物
Levy et al. Efficacy evaluation of a novel submicron amphotericin B emulsion in murine candidiasis
WO2000059472A1 (en) Propofol compositions containing preservative additives
JPH1160491A (ja) アムホテリシンｂ含有製剤
KR20000073825A (ko) 클라리스로마이신-함유 건조리포좀 조성물

Legal Events

Date Code Title Description
FZDE Discontinued