CA2041644A1 - Procede de production de derives de la progesterone - Google Patents

Procede de production de derives de la progesterone

Info

Publication number
CA2041644A1
CA2041644A1 CA002041644A CA2041644A CA2041644A1 CA 2041644 A1 CA2041644 A1 CA 2041644A1 CA 002041644 A CA002041644 A CA 002041644A CA 2041644 A CA2041644 A CA 2041644A CA 2041644 A1 CA2041644 A1 CA 2041644A1
Authority
CA
Canada
Prior art keywords
group
general formula
procedure
progesterone derivatives
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002041644A
Other languages
English (en)
Inventor
Helmut Hauser
Hans D. Berndt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2041644A1 publication Critical patent/CA2041644A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
    • C07J7/0045—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa not substituted in position 16

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA002041644A 1989-09-14 1990-09-06 Procede de production de derives de la progesterone Abandoned CA2041644A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3931064A DE3931064A1 (de) 1989-09-14 1989-09-14 Verfahren zur herstellung von progesteron-derivaten
DEP3931064.7 1989-09-14

Publications (1)

Publication Number Publication Date
CA2041644A1 true CA2041644A1 (fr) 1991-03-15

Family

ID=6389636

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002041644A Abandoned CA2041644A1 (fr) 1989-09-14 1990-09-06 Procede de production de derives de la progesterone

Country Status (10)

Country Link
US (1) US5132440A (fr)
EP (1) EP0443000B1 (fr)
JP (1) JP2837271B2 (fr)
AT (1) ATE117695T1 (fr)
CA (1) CA2041644A1 (fr)
DD (1) DD297651A5 (fr)
DE (2) DE3931064A1 (fr)
ES (1) ES2070334T3 (fr)
MX (1) MX172229B (fr)
WO (1) WO1991004265A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103467555A (zh) * 2013-03-29 2013-12-25 山东新华制药股份有限公司 17α-羟基黄体酮的合成方法
CN104072565B (zh) * 2014-07-11 2017-03-01 山东众诚药业股份有限公司 一种高收率的17α‑羟基黄体酮的简捷制备方法
CN104119415B (zh) * 2014-08-06 2017-01-25 湖南科瑞生物制药股份有限公司 一种17a‑羟基黄体酮的制备方法
CN107286215A (zh) * 2016-03-31 2017-10-24 天津金耀集团有限公司 一种多个烯烃基团的甾体化合物制备方法
CN105801651B (zh) * 2016-04-19 2018-03-06 浙江仙居君业药业有限公司 一种17α‑羟基黄体酮的合成方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2082129A5 (fr) * 1970-03-04 1971-12-10 Roussel Uclaf
US4831131A (en) * 1984-02-03 1989-05-16 The Upjohn Company 11β,17α-Dihydroxy-17β-cyano-androstanes
EP0153001B1 (fr) * 1984-02-03 1992-03-11 The Upjohn Company Stéroides porteurs d'un groupe énamide ou énimide et leur préparation
US4585590A (en) * 1984-02-03 1986-04-29 The Upjohn Company Cyanohydrin process
DE3427486A1 (de) * 1984-07-23 1986-01-30 Schering AG, Berlin und Bergkamen, 1000 Berlin Verfahren zur herstellung von 6(alpha)-methylsteroiden

Also Published As

Publication number Publication date
DE3931064A1 (de) 1991-03-28
DE59008362D1 (de) 1995-03-09
WO1991004265A1 (fr) 1991-04-04
US5132440A (en) 1992-07-21
EP0443000A1 (fr) 1991-08-28
ES2070334T3 (es) 1995-06-01
EP0443000B1 (fr) 1995-01-25
ATE117695T1 (de) 1995-02-15
MX172229B (es) 1993-12-08
JP2837271B2 (ja) 1998-12-14
DD297651A5 (de) 1992-01-16
JPH04501861A (ja) 1992-04-02

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Legal Events

Date Code Title Description
FZDE Discontinued