CA2011878A1 - Regions immunogenes sur la proteine e7 du papillomavirus humain de type 16 - Google Patents

Regions immunogenes sur la proteine e7 du papillomavirus humain de type 16

Info

Publication number
CA2011878A1
CA2011878A1 CA2011878A CA2011878A CA2011878A1 CA 2011878 A1 CA2011878 A1 CA 2011878A1 CA 2011878 A CA2011878 A CA 2011878A CA 2011878 A CA2011878 A CA 2011878A CA 2011878 A1 CA2011878 A1 CA 2011878A1
Authority
CA
Canada
Prior art keywords
protein
human papillomavirus
papillomavirus type
immunogenic regions
hpv
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2011878A
Other languages
English (en)
Other versions
CA2011878C (fr
Inventor
Dusan Bartsch
Lutz Gissmann
Martin Muller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Original Assignee
Behringwerke AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke AG filed Critical Behringwerke AG
Publication of CA2011878A1 publication Critical patent/CA2011878A1/fr
Application granted granted Critical
Publication of CA2011878C publication Critical patent/CA2011878C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA002011878A 1989-03-10 1990-03-09 Regions immunogenes sur la proteine e7 du papillomavirus humain de type 16 Expired - Fee Related CA2011878C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP3907721.7 1989-03-10
DE3907721A DE3907721A1 (de) 1989-03-10 1989-03-10 Immunogene regionen auf dem e7-protein des humanen papillomvierus typ 16

Publications (2)

Publication Number Publication Date
CA2011878A1 true CA2011878A1 (fr) 1990-09-10
CA2011878C CA2011878C (fr) 2000-05-02

Family

ID=6375965

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002011878A Expired - Fee Related CA2011878C (fr) 1989-03-10 1990-03-09 Regions immunogenes sur la proteine e7 du papillomavirus humain de type 16

Country Status (12)

Country Link
US (1) US5547846A (fr)
EP (1) EP0386734B1 (fr)
JP (1) JP3056502B2 (fr)
KR (1) KR0164215B1 (fr)
AT (1) ATE128144T1 (fr)
AU (1) AU624485B2 (fr)
CA (1) CA2011878C (fr)
DE (2) DE3907721A1 (fr)
DK (1) DK0386734T3 (fr)
ES (1) ES2078255T3 (fr)
IE (1) IE67798B1 (fr)
PT (1) PT93393B (fr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2038581A1 (fr) * 1990-03-20 1991-09-21 Martin Muller Determinants antigeniques sereux des proteines 16 du virus des papillomes humains (vph)
SE9001705D0 (sv) * 1990-05-11 1990-05-11 Medscand Ab Saett foer diagnostik av virusbaerande tumoerer genom immunoassay
US5932412A (en) * 1990-05-11 1999-08-03 Euro-Diagnostica Ab Synthetic peptides in human papillomaviruses 1, 5, 6, 8, 11, 16, 18, 31, 33 and 56, useful in immunoassay for diagnostic purposes
US6183745B1 (en) 1990-12-12 2001-02-06 The University Of Queensland Subunit papilloma virus vaccine and peptides for use therein
ES2193133T3 (es) * 1991-07-13 2003-11-01 Dade Behring Marburg Gmbh Uso de peptidos derivados de los genes e6 y e7 de hpv-16 para fines.
IL105554A (en) * 1992-05-05 1999-08-17 Univ Leiden Peptides of human papillomavirus for use in preparations elicit a human T cell response
GB9717953D0 (en) 1997-08-22 1997-10-29 Smithkline Beecham Biolog Vaccine
DE19737409A1 (de) * 1997-08-27 1999-03-04 Medigene Ag Diagnosekit für Hauttest und Verfahren zur Durchführung desselben
US6013258A (en) * 1997-10-09 2000-01-11 Zycos Inc. Immunogenic peptides from the HPV E7 protein
US6183746B1 (en) 1997-10-09 2001-02-06 Zycos Inc. Immunogenic peptides from the HPV E7 protein
DE19819476C1 (de) * 1998-04-30 2000-01-05 Deutsches Krebsforsch Polypeptid mit immunogenen Eigenschaften und veränderten biologischen Funktionen eines Proteins
FR2781158B1 (fr) * 1998-07-15 2002-12-13 Vacs Internat Nouvelles proteines modifiees immunogenes non immunosuppressives, leur procede de preparation et leurs applications
DE19925199A1 (de) 1999-06-01 2000-12-07 Medigene Ag Zytotoxische T-Zellepitope des Papillomavirus L1-Proteins und ihre Verwendung in Diagnostik und Therapie
DE19925235A1 (de) 1999-06-01 2000-12-07 Medigene Ag Zytotoxische T-Zellepitope des Papillomavirus L1-Proteins und ihre Verwendung in Diagnostik und Therapie
US6200746B1 (en) 1999-08-25 2001-03-13 Pharmacia & Upjohn Company Methods of identifying anti-viral agents
US6641994B2 (en) 1999-08-25 2003-11-04 Pharmacia & Upjohn Company Methods of identifying anti-viral agents
US20050100928A1 (en) * 1999-09-16 2005-05-12 Zycos Inc., A Delaware Corporation Nucleic acids encoding polyepitope polypeptides
US8128922B2 (en) * 1999-10-20 2012-03-06 Johns Hopkins University Superior molecular vaccine linking the translocation domain of a bacterial toxin to an antigen
GB0018050D0 (en) * 2000-07-21 2000-09-13 Norchip As Detection of human papillomavirus mRNA
US7318928B2 (en) * 2000-08-01 2008-01-15 The Johns Hopkins University Molecular vaccine linking intercellular spreading protein to an antigen
AU2001278117A1 (en) * 2000-08-03 2002-02-18 Johns Hopkins University Molecular vaccine linking an endoplasmic reticulum chaperone polypeptide to an antigen
CA2441947C (fr) 2001-03-23 2014-05-13 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Peptides immunoreactifs du papillomavirus humain
GB0120938D0 (en) * 2001-08-29 2001-10-17 Norchip As Detection of human papillomavirus E7 mRNA
AU2003284239B2 (en) * 2002-10-21 2008-08-21 Eisai Inc. Compositions and methods for treating human papillomavirus-mediated disease
WO2004098526A2 (fr) * 2003-05-05 2004-11-18 Johns Hopkins University Vaccin a adn anti-cancer faisant appel a des plasmides codant une sequence-signal, un antigene oncoproteine mutant, et une proteine de choc thermique
WO2006073970A2 (fr) * 2005-01-06 2006-07-13 The Johns Hopkins University Interference arn bloquant l'expression de l'immunite potentialisee de proteines pro-apoptotiques induite par adn et des vaccins de cellules dendritiques transfectes
CA2595726A1 (fr) * 2005-01-26 2006-08-03 The Johns Hopkins University Vaccin d'adn anticancereux utilisant des plasmides codant un antigene et une calreticuline tels que des oncoproteines mutantes
WO2008024844A2 (fr) * 2006-08-22 2008-02-28 The Johns Hopkins University Combinaisons thérapeutiques anticancers
US9085638B2 (en) 2007-03-07 2015-07-21 The Johns Hopkins University DNA vaccine enhancement with MHC class II activators
US20080260765A1 (en) * 2007-03-15 2008-10-23 Johns Hopkins University HPV DNA Vaccines and Methods of Use Thereof
CU23674A1 (es) 2007-07-31 2011-05-27 Ct Ingenieria Genetica Biotech Péptidos penetradores a células fusionados a una biomolécula con acción terapéutica
US20090285861A1 (en) * 2008-04-17 2009-11-19 Tzyy-Choou Wu Tumor cell-based cancer immunotherapeutic compositions and methods

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4777239A (en) * 1986-07-10 1988-10-11 The Board Of Trustees Of The Leland Stanford Junior University Diagnostic peptides of human papilloma virus
DE3722967A1 (de) * 1987-07-11 1989-01-19 Behringwerke Ag Monoklonale antikoerper gegen e7-protein des humanen papillomvirus typ 16, verfahren zu ihrer herstellung sowie ihre verwendung
FR2641081A1 (fr) * 1988-12-23 1990-06-29 Medgenix Group
JP2791685B2 (ja) * 1989-06-08 1998-08-27 寳酒造株式会社 パピローマウイルスの検出方法
CA2038581A1 (fr) * 1990-03-20 1991-09-21 Martin Muller Determinants antigeniques sereux des proteines 16 du virus des papillomes humains (vph)

Also Published As

Publication number Publication date
EP0386734A3 (fr) 1992-03-04
EP0386734B1 (fr) 1995-09-20
DE3907721A1 (de) 1990-09-20
PT93393A (pt) 1990-11-07
DK0386734T3 (da) 1996-02-05
IE900854L (en) 1990-09-10
EP0386734A2 (fr) 1990-09-12
JPH02289600A (ja) 1990-11-29
KR0164215B1 (ko) 1999-01-15
DE59009669D1 (de) 1995-10-26
PT93393B (pt) 1997-01-31
IE67798B1 (en) 1996-05-01
AU5110490A (en) 1990-09-13
AU624485B2 (en) 1992-06-11
JP3056502B2 (ja) 2000-06-26
CA2011878C (fr) 2000-05-02
ES2078255T3 (es) 1995-12-16
US5547846A (en) 1996-08-20
KR900013979A (ko) 1990-10-22
ATE128144T1 (de) 1995-10-15

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