CA2014884A1 - 5,11-dihydro-6h-pyrido[2,3-b] [1,4] benzodiazepin-6-ones et-thiones et leur utilisation dans la prevention ou le traitement du sida - Google Patents

5,11-dihydro-6h-pyrido[2,3-b] [1,4] benzodiazepin-6-ones et-thiones et leur utilisation dans la prevention ou le traitement du sida

Info

Publication number
CA2014884A1
CA2014884A1 CA2014884A CA2014884A CA2014884A1 CA 2014884 A1 CA2014884 A1 CA 2014884A1 CA 2014884 A CA2014884 A CA 2014884A CA 2014884 A CA2014884 A CA 2014884A CA 2014884 A1 CA2014884 A1 CA 2014884A1
Authority
CA
Canada
Prior art keywords
benzodiazepin
pyrido
dihydro
ones
thiones
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2014884A
Other languages
English (en)
Other versions
CA2014884C (fr
Inventor
Gunther Schmidt (Deceased)
Wolfhard Engel
Volkhard Austel
Karl D. Hargrave
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Boehringer Ingelheim Pharmaceuticals Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2014884A1 publication Critical patent/CA2014884A1/fr
Application granted granted Critical
Publication of CA2014884C publication Critical patent/CA2014884C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CA002014884A 1989-04-20 1990-04-19 5,11-dihydro-6h-pyrido[2,3-b] [1,4] benzodiazepin-6-ones et-thiones et leur utilisation dans la prevention ou le traitement du sida Expired - Fee Related CA2014884C (fr)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US34093789A 1989-04-20 1989-04-20
US07/340,937 1989-04-20
US37272889A 1989-06-28 1989-06-28
US07/372,728 1989-06-28
US43892289A 1989-11-17 1989-11-17
US07/438,922 1989-11-17

Publications (2)

Publication Number Publication Date
CA2014884A1 true CA2014884A1 (fr) 1990-10-20
CA2014884C CA2014884C (fr) 1999-09-07

Family

ID=27407433

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002014884A Expired - Fee Related CA2014884C (fr) 1989-04-20 1990-04-19 5,11-dihydro-6h-pyrido[2,3-b] [1,4] benzodiazepin-6-ones et-thiones et leur utilisation dans la prevention ou le traitement du sida

Country Status (8)

Country Link
EP (1) EP0393530B1 (fr)
JP (1) JP2911956B2 (fr)
AT (1) ATE116320T1 (fr)
CA (1) CA2014884C (fr)
DE (1) DE69015411T2 (fr)
DK (1) DK0393530T3 (fr)
ES (1) ES2066897T3 (fr)
GR (1) GR3015469T3 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0475231A1 (fr) * 1990-09-10 1992-03-18 F. Hoffmann-La Roche Ag Benzodiazépines
GB9109557D0 (en) * 1991-05-02 1991-06-26 Wellcome Found Chemical compounds
WO1994017075A1 (fr) * 1993-01-20 1994-08-04 A. Menarini Industrie Farmaceutiche Riunite S.R.L. Derives de diazepine et compositions antivirales
US6593337B1 (en) * 1999-10-19 2003-07-15 Bristol-Myers Squibb Pharma Company Tricyclic compounds useful as HIV reverse transcriptase inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1542160A (fr) * 1966-10-31 1968-10-11 Thomae Gmbh Dr K Procédé de fabrication de nouvelles 5, 11-dihydro-6h-pyrido-[2, 3-b] [1, 4]-benzodiazépine-6-ones substituées en position 11

Also Published As

Publication number Publication date
EP0393530A1 (fr) 1990-10-24
DE69015411D1 (de) 1995-02-09
EP0393530B1 (fr) 1994-12-28
ES2066897T3 (es) 1995-03-16
JP2911956B2 (ja) 1999-06-28
ATE116320T1 (de) 1995-01-15
CA2014884C (fr) 1999-09-07
DK0393530T3 (da) 1995-05-22
DE69015411T2 (de) 1995-05-24
JPH0363275A (ja) 1991-03-19
GR3015469T3 (en) 1995-06-30

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