CA1337754C - Composes fluorescents a base de phtalocyanine et de tetrabenztriazaporphyrine, avec decalage vers le rouge - Google Patents

Composes fluorescents a base de phtalocyanine et de tetrabenztriazaporphyrine, avec decalage vers le rouge

Info

Publication number
CA1337754C
CA1337754C CA000610514A CA610514A CA1337754C CA 1337754 C CA1337754 C CA 1337754C CA 000610514 A CA000610514 A CA 000610514A CA 610514 A CA610514 A CA 610514A CA 1337754 C CA1337754 C CA 1337754C
Authority
CA
Canada
Prior art keywords
aluminum
dna
reagent
group
phthalocyanine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA000610514A
Other languages
English (en)
Inventor
Deborah C. Schindele
Louis J. Theodore
George E. Renzoni
Clifford C. Leznoff
Barry V. Pepich
Karen L. Fearon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BTG International Inc
Original Assignee
British Technology Group USA Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/398,433 external-priority patent/US5135717A/en
Application filed by British Technology Group USA Inc filed Critical British Technology Group USA Inc
Application granted granted Critical
Publication of CA1337754C publication Critical patent/CA1337754C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Urology & Nephrology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA000610514A 1988-09-08 1989-09-07 Composes fluorescents a base de phtalocyanine et de tetrabenztriazaporphyrine, avec decalage vers le rouge Expired - Fee Related CA1337754C (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US24160888A 1988-09-08 1988-09-08
US241,608 1988-09-08
US398,433 1989-08-29
US07/398,433 US5135717A (en) 1986-12-24 1989-08-29 Tetrabenztriazaporphyrin reagents and kits containing the same

Publications (1)

Publication Number Publication Date
CA1337754C true CA1337754C (fr) 1995-12-19

Family

ID=26934432

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000610514A Expired - Fee Related CA1337754C (fr) 1988-09-08 1989-09-07 Composes fluorescents a base de phtalocyanine et de tetrabenztriazaporphyrine, avec decalage vers le rouge

Country Status (5)

Country Link
EP (1) EP0434727A4 (fr)
JP (1) JPH04500516A (fr)
AU (1) AU642396B2 (fr)
CA (1) CA1337754C (fr)
WO (1) WO1990002747A1 (fr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5567687A (en) * 1989-03-06 1996-10-22 University Of Texas Texaphyrins and uses thereof
JPH05501857A (ja) * 1989-06-07 1993-04-08 ザ ユニバーシティー オブ ブリティッシュ コロンビア 感光性ディールス―アルダーポルフィリン誘導体
US5053423A (en) * 1990-03-22 1991-10-01 Quadra Logic Technologies Inc. Compositions for photodynamic therapy
US5238940A (en) * 1990-03-22 1993-08-24 Quadra Logic Technologies Inc. Compositions for photodynamic therapy
US5880287A (en) * 1990-05-15 1999-03-09 Hyperion, Inc. Polyoxyhydrocarbyl related products and methods for fluorescence assays
US6060598A (en) * 1990-05-15 2000-05-09 Hyperion, Inc. Fluorescence immunoassays using fluorescent dyes free of aggregation and serum binding
US5919922A (en) * 1990-05-15 1999-07-06 Hyperion, Inc. Fluorescent dyes free of aggregation and serum binding
EP0502723B1 (fr) * 1991-03-05 1996-10-09 Hitachi Chemical Co., Ltd. Tétraazaporphine soluble dans l'eau et fluorochrome pour marquer
US5595726A (en) * 1992-01-21 1997-01-21 Pharmacyclics, Inc. Chromophore probe for detection of nucleic acid
US5565552A (en) * 1992-01-21 1996-10-15 Pharmacyclics, Inc. Method of expanded porphyrin-oligonucleotide conjugate synthesis
US5607924A (en) * 1992-01-21 1997-03-04 Pharmacyclics, Inc. DNA photocleavage using texaphyrins
JP3208942B2 (ja) * 1992-11-10 2001-09-17 日立化成工業株式会社 水溶性テトラアザポルフィン、蛍光標識用色素、標識された生物由来物質、これらを含有する試薬及びこれらを用いた蛍光分析法
JP3260884B2 (ja) * 1993-02-05 2002-02-25 キヤノン株式会社 標識複合体、それを用いる分析法、生体関連物質の検出および定量の方法
US5798491A (en) * 1993-06-09 1998-08-25 Board Of Regents, The University Of Texas System Multi-mechanistic chemical cleavage using certain metal complexes
GB9317881D0 (en) * 1993-08-27 1993-10-13 Secr Defence Photosensitizers
US5837866A (en) * 1994-09-21 1998-11-17 Board Of Regents, The University Of Texas Phosphoramidite derivatives of macrocycles
US5633354A (en) * 1994-09-21 1997-05-27 Pharmacyclics, Inc. Phosphoramidite derivatives of texaphyrins
WO1996011937A1 (fr) * 1994-10-14 1996-04-25 Stratagene Marquage de polynucleotides par porphyrines
US5714328A (en) * 1995-06-07 1998-02-03 Board Of Regents, The University Of Texas System RNA photocleavage using texaphyrins
DE19539409C2 (de) * 1995-10-11 1999-02-18 Diagnostikforschung Inst Kontrastmittel für die Nahinfrarot-Diagnostik
US6022959A (en) * 1996-08-20 2000-02-08 Pharmacyclics, Inc. Nucleic acids internally-derivatized with a texaphyrin metal complex and uses thereof
CA2350608A1 (fr) * 1998-11-25 2000-06-02 Hyperion, Inc. Colorants fluorescents solubles dans l'eau sans agregation et sans liaison au serum, produits et procedes associes
KR100502112B1 (ko) * 1999-12-28 2005-07-19 미쯔이카가쿠 가부시기가이샤 추기형 광기록매체
US6573258B2 (en) * 2000-09-27 2003-06-03 Frontier Scientific, Inc. Photodynamic porphyrin antimicrobial agents
DE60204767T2 (de) * 2001-03-21 2006-05-18 L. Molteni & C. dei Fratelli Alitti Società di Esercizio S.p.A. Metallsubstituierte, nicht zentrosymmetrische phthalocyanin-analoga, deren herstellung und verwendung zur photodynamischen therapie, und als in-vivo-diagnostikum
US7371524B2 (en) * 2003-06-17 2008-05-13 Hannjorg Hereth Substituted azaporphyrins as fluorescence labels
US20070065826A1 (en) * 2003-09-05 2007-03-22 Ebara Corporation Cationic dye compound for detecting nucleic acid double strand, and detection method and apparatus using same
JP4648637B2 (ja) * 2004-02-04 2011-03-09 株式会社日本触媒 カルボキシル基および／またはスルホン酸基を有するフタロシアニン化合物ならびにその製造方法
US8524891B2 (en) 2005-07-14 2013-09-03 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Tetraazaporphyrin-based compounds and their uses
FR2889700B1 (fr) * 2005-08-11 2012-11-23 Synthinnove Lab Marqueurs, leur procede de fabrication et leurs applications
CN105820170B (zh) * 2016-05-05 2019-11-19 厦门大学 以三正辛基膦为溶剂合成磺基金属酞菁荧光化合物的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4394125A (en) * 1980-09-09 1983-07-19 Ciba-Geigy Corporation Process for bleaching textiles and for combating micro-organisms with sulfonated phthalocyanine of aluminum or zinc and containing halogen or cyano substituents as photoactivator
US4803170A (en) * 1985-05-09 1989-02-07 Ultra Diagnostics Corporation Competitive immunoassay method, device and test kit
CA1340806C (fr) * 1986-07-02 1999-11-02 James Merrill Prober Methode, systeme et reactifs pour le sequencage de l'adn
EP0335902B1 (fr) * 1986-12-15 1993-12-01 British Technology Group Usa Inc. Reactifs de phtalocyanine monomeres
GB8705575D0 (en) * 1987-03-10 1987-04-15 Ici Plc Substituted phthalocyanine

Also Published As

Publication number Publication date
WO1990002747A1 (fr) 1990-03-22
JPH04500516A (ja) 1992-01-30
AU4216389A (en) 1990-04-02
EP0434727A1 (fr) 1991-07-03
EP0434727A4 (en) 1994-08-17
AU642396B2 (en) 1993-10-21

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