CA1311686C - Controlled release bioerodible drug delivery system - Google Patents
Controlled release bioerodible drug delivery systemInfo
- Publication number
- CA1311686C CA1311686C CA000540361A CA540361A CA1311686C CA 1311686 C CA1311686 C CA 1311686C CA 000540361 A CA000540361 A CA 000540361A CA 540361 A CA540361 A CA 540361A CA 1311686 C CA1311686 C CA 1311686C
- Authority
- CA
- Canada
- Prior art keywords
- drug
- dosage form
- matrix
- microparticles
- ocular
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1658—Proteins, e.g. albumin, gelatin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87827286A | 1986-06-25 | 1986-06-25 | |
| US878,272 | 1986-06-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1311686C true CA1311686C (en) | 1992-12-22 |
Family
ID=25371703
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000540361A Expired - Lifetime CA1311686C (en) | 1986-06-25 | 1987-06-23 | Controlled release bioerodible drug delivery system |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0251680B1 (forum.php) |
| JP (1) | JPS6322516A (forum.php) |
| AT (1) | ATE74752T1 (forum.php) |
| AU (1) | AU606872B2 (forum.php) |
| CA (1) | CA1311686C (forum.php) |
| DE (1) | DE3778223D1 (forum.php) |
| ES (1) | ES2037082T3 (forum.php) |
| GR (1) | GR3004710T3 (forum.php) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016196365A1 (en) * | 2015-05-29 | 2016-12-08 | Envisia Therapeutics, Inc. | Implant for treatment of an ocular condition |
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| US8722097B2 (en) | 2004-04-30 | 2014-05-13 | Allergan, Inc. | Oil-in-water method for making polymeric implants containing a hypotensive lipid |
| US7799336B2 (en) | 2004-04-30 | 2010-09-21 | Allergan, Inc. | Hypotensive lipid-containing biodegradable intraocular implants and related methods |
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| CN102281870B (zh) | 2008-12-10 | 2015-03-04 | 安徽中人科技有限责任公司 | 新型控释组合物 |
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| US10286146B2 (en) | 2011-03-14 | 2019-05-14 | Minipumps, Llc | Implantable drug pumps and refill devices therefor |
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| WO2019016686A1 (en) * | 2017-07-17 | 2019-01-24 | Wolfcreek Biotech Pte Ltd | MICROPARTICLE FORMULATIONS FOR THE ADMINISTRATION OF ACTIVE AGENTS |
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| US3981303A (en) * | 1971-09-09 | 1976-09-21 | Alza Corporation | Bioerodible ocular device |
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| IE58110B1 (en) * | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
-
1987
- 1987-06-23 CA CA000540361A patent/CA1311686C/en not_active Expired - Lifetime
- 1987-06-24 AU AU74650/87A patent/AU606872B2/en not_active Expired - Fee Related
- 1987-06-24 DE DE8787305625T patent/DE3778223D1/de not_active Expired - Lifetime
- 1987-06-24 ES ES198787305625T patent/ES2037082T3/es not_active Expired - Lifetime
- 1987-06-24 AT AT87305625T patent/ATE74752T1/de not_active IP Right Cessation
- 1987-06-24 JP JP62155622A patent/JPS6322516A/ja active Pending
- 1987-06-24 EP EP87305625A patent/EP0251680B1/en not_active Expired - Lifetime
-
1992
- 1992-05-26 GR GR920401046T patent/GR3004710T3/el unknown
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016196365A1 (en) * | 2015-05-29 | 2016-12-08 | Envisia Therapeutics, Inc. | Implant for treatment of an ocular condition |
| US20180177718A1 (en) * | 2015-05-29 | 2018-06-28 | Envisia Therapeutics, Inc. | Implant for treatment of an ocular condition |
| EP4566638A3 (en) * | 2015-05-29 | 2025-08-27 | Allergan, Inc. | Implant for treatment of an ocular condition |
Also Published As
| Publication number | Publication date |
|---|---|
| DE3778223D1 (de) | 1992-05-21 |
| GR3004710T3 (forum.php) | 1993-04-28 |
| EP0251680A2 (en) | 1988-01-07 |
| AU7465087A (en) | 1988-01-07 |
| ATE74752T1 (de) | 1992-05-15 |
| JPS6322516A (ja) | 1988-01-30 |
| AU606872B2 (en) | 1991-02-21 |
| EP0251680A3 (en) | 1988-02-24 |
| EP0251680B1 (en) | 1992-04-15 |
| ES2037082T3 (es) | 1993-06-16 |
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