CA1275062A - Kym activateur de plasminogene - Google Patents

Kym activateur de plasminogene

Info

Publication number
CA1275062A
CA1275062A CA000472999A CA472999A CA1275062A CA 1275062 A CA1275062 A CA 1275062A CA 000472999 A CA000472999 A CA 000472999A CA 472999 A CA472999 A CA 472999A CA 1275062 A CA1275062 A CA 1275062A
Authority
CA
Canada
Prior art keywords
substance
kym
cells
culture
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA000472999A
Other languages
English (en)
Inventor
Masaru Imada
Yoshihiro Yoshiyama
Munehiro Oda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Meiji Dairies Corp
Original Assignee
Meiji Milk Products Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Milk Products Co Ltd filed Critical Meiji Milk Products Co Ltd
Application granted granted Critical
Publication of CA1275062A publication Critical patent/CA1275062A/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6462—Plasminogen activators u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21073—Serine endopeptidases (3.4.21) u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA000472999A 1984-01-30 1985-01-28 Kym activateur de plasminogene Expired - Fee Related CA1275062A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP59013397A JPS60158115A (ja) 1984-01-30 1984-01-30 プラズミノーゲンアクチベーターの製造法
JP59-013397 1984-01-30

Publications (1)

Publication Number Publication Date
CA1275062A true CA1275062A (fr) 1990-10-09

Family

ID=11831979

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000472999A Expired - Fee Related CA1275062A (fr) 1984-01-30 1985-01-28 Kym activateur de plasminogene

Country Status (7)

Country Link
JP (1) JPS60158115A (fr)
BE (1) BE901598A (fr)
CA (1) CA1275062A (fr)
DE (1) DE3502760A1 (fr)
FR (1) FR2558848B1 (fr)
GB (1) GB2153366B (fr)
NL (1) NL8500132A (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6427472A (en) * 1987-07-21 1989-01-30 Meiji Milk Prod Co Ltd Production of human tissue plasminogen activator and cell strain using therein

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3015699C2 (de) * 1979-04-26 1982-07-15 Asahi Kasei Kogyo K.K., Osaka Herstellung eines Plasminogen-Aktivators
EP0040238B1 (fr) * 1979-11-13 1984-07-11 HUSAIN, Syed Shaukat Activateurs plasminogenes utilies comme agents therapeutiques et diagnostiques et leur isolation
NL8003402A (nl) * 1980-06-11 1982-01-04 Leuven Res & Dev Vzw Nieuwe plasminogeen-activator en farmaceutisch preparaat met trombolytische werking.
JPS5852634B2 (ja) * 1980-12-05 1983-11-24 株式会社林原生物化学研究所 ウロキナ−ゼの製造法
IL63317A (en) * 1981-07-15 1985-05-31 Yeda Res & Dev Production of plasminogen activator
ZA831399B (en) * 1982-03-05 1984-02-29 Health Lab Service Board New fibrinolytic enzymes and methods for their production and pharmaceutical compositions containing them
JPS5913732A (ja) * 1982-07-16 1984-01-24 Mitsui Toatsu Chem Inc 血栓溶解剤
JPS5951220A (ja) * 1982-08-02 1984-03-24 Asahi Chem Ind Co Ltd 新規なプラスミノ−ゲン・アクチベ−タ−およびその製法ならびにこれを含有する薬剤

Also Published As

Publication number Publication date
GB2153366B (en) 1988-05-18
NL8500132A (nl) 1985-08-16
GB2153366A (en) 1985-08-21
JPS60158115A (ja) 1985-08-19
BE901598A (fr) 1985-07-29
FR2558848B1 (fr) 1989-06-09
GB8501532D0 (en) 1985-02-20
JPH0569506B2 (fr) 1993-10-01
FR2558848A1 (fr) 1985-08-02
DE3502760A1 (de) 1985-08-08

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US5139939A (en) Process for the production of human tissue plasminogen activator and cell strain useful therefor
JPS62158219A (ja) ヒト由来組織型プラスミノ−ゲン活性化因子、その製造方法及びこれを有効成分とする血栓溶解剤
EP0227102A2 (fr) Lignée cellulaire établie à partir de muscle utérin normal humain, méthode de production d'activateur de plasminogène à partir de cette lignée cellulaire et activateur de plasminogène
JPH01256384A (ja) 組織型プラスミノーゲン活性化因子及びその製造法
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JPH01256385A (ja) 組織型プラスミノーゲン活性化因子の製造法
JPH0358270B2 (fr)

Legal Events

Date Code Title Description
MKLA Lapsed