CA1216845A - Process for the preparation of cyclic hexapeptide - Google Patents

Process for the preparation of cyclic hexapeptide

Info

Publication number
CA1216845A
CA1216845A CA000407186A CA407186A CA1216845A CA 1216845 A CA1216845 A CA 1216845A CA 000407186 A CA000407186 A CA 000407186A CA 407186 A CA407186 A CA 407186A CA 1216845 A CA1216845 A CA 1216845A
Authority
CA
Canada
Prior art keywords
tyr
ala
phe
trp
lys
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000407186A
Other languages
English (en)
French (fr)
Inventor
Ruth F. Nutt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of CA1216845A publication Critical patent/CA1216845A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/16—Somatostatin; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA000407186A 1981-07-15 1982-07-13 Process for the preparation of cyclic hexapeptide Expired CA1216845A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US283,404 1981-07-15
US06/283,404 US4374060A (en) 1981-07-15 1981-07-15 Process for the preparation of cyclic hexapeptide

Publications (1)

Publication Number Publication Date
CA1216845A true CA1216845A (en) 1987-01-20

Family

ID=23085903

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000407186A Expired CA1216845A (en) 1981-07-15 1982-07-13 Process for the preparation of cyclic hexapeptide

Country Status (9)

Country Link
US (1) US4374060A (OSRAM)
EP (1) EP0070021B1 (OSRAM)
JP (1) JPS5818345A (OSRAM)
AT (1) ATE17359T1 (OSRAM)
CA (1) CA1216845A (OSRAM)
DK (1) DK316382A (OSRAM)
ES (1) ES513937A0 (OSRAM)
GR (1) GR76860B (OSRAM)
PT (1) PT75192B (OSRAM)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4584172A (en) * 1982-09-27 1986-04-22 Aluminum Company Of America Method of making composition suitable for use as inert electrode having good electrical conductivity and mechanical properties
JPS59148124A (ja) * 1983-02-15 1984-08-24 Konishiroku Photo Ind Co Ltd 磁気記録媒体の製造方法
US4508711A (en) * 1983-04-18 1985-04-02 American Cyanamid Company Cyclic pentapeptide displaying somatostatin antagonism and method of treatment of mammals therewith
DE3822557C2 (de) * 1987-07-10 1998-07-02 Ciba Geigy Ag Arzneimittel, enthaltend Somatostatine
FR2645870B1 (fr) * 1989-04-12 1993-01-22 Bioetica Sa Procede de reticulation du collagene par le diphenylphosphorylazide, collagene reticule ainsi obtenu et biomateriaux a base de collagene ainsi reticules
US6117841A (en) * 1997-05-30 2000-09-12 Warner-Lambert Company Substituted peptidylamine calcium channel blockers
JPWO2020262590A1 (OSRAM) * 2019-06-28 2020-12-30
CN116621941B (zh) * 2022-05-19 2024-07-09 浙江湃肽生物股份有限公司 一种抗皮肤衰老环六肽类化合物及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4102877A (en) * 1976-07-28 1978-07-25 Merck & Co., Inc. Cyclization of peptides
CA1101843A (en) * 1976-08-02 1981-05-26 Daniel F. Veber Cyclic hexapeptides useful for increasing feed efficiency
SU1219587A1 (ru) * 1978-09-29 1986-03-23 Ордена Трудового Красного Знамени Институт Органического Синтеза Ан Латвсср Циклические аналоги каллидина и других пахикининов,обладающие пролонгированным гипотензивным действием в сочетании с низкой или полностью отсутствующей миотропной активностью
US4310518A (en) * 1979-10-31 1982-01-12 Merck & Co., Inc. Cyclic hexapeptide somatostatin analogs
NZ195303A (en) * 1979-10-31 1984-10-19 Merck & Co Inc Cyclic hexapeptide somatostatin analogues,and pharmaceutical compositions
US4235886A (en) * 1979-10-31 1980-11-25 Merck & Co., Inc. Cyclic hexapeptide somatostatin analogs

Also Published As

Publication number Publication date
EP0070021A1 (en) 1983-01-19
DK316382A (da) 1983-01-16
PT75192B (en) 1985-10-04
ES8305702A1 (es) 1983-04-16
EP0070021B1 (en) 1986-01-08
JPS5818345A (ja) 1983-02-02
ATE17359T1 (de) 1986-01-15
PT75192A (en) 1982-08-01
GR76860B (OSRAM) 1984-09-04
ES513937A0 (es) 1983-04-16
US4374060A (en) 1983-02-15

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Legal Events

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