CA1176253A - 2-[3-[4-(3-chloro-4-fluorophenyl)-1- piperazinyl]propyl]-1,2,4-triazolo[4,3-a] pyridin-3 (2h)-one - Google Patents

2-[3-[4-(3-chloro-4-fluorophenyl)-1- piperazinyl]propyl]-1,2,4-triazolo[4,3-a] pyridin-3 (2h)-one

Info

Publication number
CA1176253A
CA1176253A CA000374133A CA374133A CA1176253A CA 1176253 A CA1176253 A CA 1176253A CA 000374133 A CA000374133 A CA 000374133A CA 374133 A CA374133 A CA 374133A CA 1176253 A CA1176253 A CA 1176253A
Authority
CA
Canada
Prior art keywords
chloro
pyridin
propyl
triazolo
piperazinyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000374133A
Other languages
English (en)
French (fr)
Inventor
Bruno Silvestrini
Leandro Baiocchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Angelini Acraf SpA
Original Assignee
Aziende Chimiche Riunite Angelini Francesco ACRAF SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aziende Chimiche Riunite Angelini Francesco ACRAF SpA filed Critical Aziende Chimiche Riunite Angelini Francesco ACRAF SpA
Application granted granted Critical
Publication of CA1176253A publication Critical patent/CA1176253A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CA000374133A 1980-04-09 1981-03-30 2-[3-[4-(3-chloro-4-fluorophenyl)-1- piperazinyl]propyl]-1,2,4-triazolo[4,3-a] pyridin-3 (2h)-one Expired CA1176253A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT21246A/80 1980-04-09
IT21246/80A IT1147349B (it) 1980-04-09 1980-04-09 2-parentesi quadra aperta 3-parentesi quadra aperta 4-(3-cloro-4-fluorofenil)-1-piperfrazinil parentesi quadra propil parentesi quadra chiusa-1,2,4-triazolo parentesi quadra aperta 4,3 parentesi quadra chiusa piridin-3(2h)-one

Publications (1)

Publication Number Publication Date
CA1176253A true CA1176253A (en) 1984-10-16

Family

ID=11178966

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000374133A Expired CA1176253A (en) 1980-04-09 1981-03-30 2-[3-[4-(3-chloro-4-fluorophenyl)-1- piperazinyl]propyl]-1,2,4-triazolo[4,3-a] pyridin-3 (2h)-one

Country Status (21)

Country Link
US (1) US4402956A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS56158784A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR840002292B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AR (1) AR225076A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) AT377262B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU529605B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE887547A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1176253A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH652397A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3112984A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES501188A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI69306C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2480285A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2073747B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR73620B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL62101A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1147349B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL8100998A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT72813B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE442201B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
YU (1) YU83181A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2269608A1 (en) 1996-11-12 1998-05-22 Sepracor Inc. 2r,4s,s,s- and 2s,4r,s,s-hydroxyitraconazole
AU5178998A (en) * 1996-11-12 1998-06-03 Sepracor, Inc. 2(r),4(s),(r),(s)- and 2(s),4(r),(r),(s)-hydroxyitraconazole- and hydroxysaperconazole derivatives
US6147077A (en) * 1999-04-29 2000-11-14 Sepracor Inc. 2R,4S-hydroxyitraconazole isomers
US8686158B2 (en) * 2008-06-05 2014-04-01 President And Fellows Of Harvard College High-valent palladium fluoride complexes and uses thereof
CA2742869A1 (en) 2008-11-20 2010-05-27 President And Fellows Of Harvard College Fluorination of organic compounds
JP2012514655A (ja) * 2009-01-09 2012-06-28 プレジデント アンド フェローズ オブ ハーバード カレッジ フッ素含有化合物およびその使用法
US9150516B2 (en) 2011-04-12 2015-10-06 President And Fellows Of Harvard College Fluorination of organic compounds
US9273083B2 (en) 2012-09-26 2016-03-01 President And Fellows Of Harvard College Nickel fluorinating complexes and uses thereof
WO2015058047A2 (en) 2013-10-18 2015-04-23 President And Fellows Of Harvard College Fluorination of organic compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1066857B (it) * 1965-12-15 1985-03-12 Acraf Derivati della s ipiazolo 4.3 a piridina e processi per la loro preparazione
FR8135M (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1968-12-31 1970-08-10
US4218458A (en) * 1978-06-23 1980-08-19 Janssen Pharmaceutica, N.V. Heterocyclic derivatives of (4-aryloxy-methyl-1,3-dioxolan-2-yl)methyl-1H-imidazoles and 1H-1,2,4-triazoles
UST100505I4 (en) 1980-03-17 1981-04-07 Triazolo[4,3-a]pyridin-3(2H)-ones

Also Published As

Publication number Publication date
FR2480285A1 (fr) 1981-10-16
CH652397A5 (it) 1985-11-15
GB2073747B (en) 1983-09-07
PT72813A (en) 1981-05-01
FR2480285B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1984-02-24
FI811000L (fi) 1981-10-10
FI69306C (fi) 1986-01-10
AR225076A1 (es) 1982-02-15
NL8100998A (nl) 1981-11-02
JPS56158784A (en) 1981-12-07
ES8202817A1 (es) 1982-02-01
KR840002292B1 (ko) 1984-12-15
GB2073747A (en) 1981-10-21
ATA165081A (de) 1984-07-15
US4402956A (en) 1983-09-06
IL62101A0 (en) 1981-03-31
FI69306B (fi) 1985-09-30
KR830005218A (ko) 1983-08-03
YU83181A (en) 1983-12-31
AU6904381A (en) 1981-10-15
GR73620B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1984-03-26
BE887547A (fr) 1981-06-15
SE8102093L (sv) 1981-10-10
SE442201B (sv) 1985-12-09
AT377262B (de) 1985-02-25
IT1147349B (it) 1986-11-19
DE3112984A1 (de) 1981-12-24
IT8021246A0 (it) 1980-04-09
IL62101A (en) 1984-01-31
PT72813B (en) 1982-04-02
ES501188A0 (es) 1982-02-01
AU529605B2 (en) 1983-06-16

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