CA1171860A - Oxazolidinedione derivatives - Google Patents
Oxazolidinedione derivativesInfo
- Publication number
- CA1171860A CA1171860A CA000413239A CA413239A CA1171860A CA 1171860 A CA1171860 A CA 1171860A CA 000413239 A CA000413239 A CA 000413239A CA 413239 A CA413239 A CA 413239A CA 1171860 A CA1171860 A CA 1171860A
- Authority
- CA
- Canada
- Prior art keywords
- hydrogen
- spiro
- trione
- oxazolidine
- indoline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31068281A | 1981-10-13 | 1981-10-13 | |
| US310,682 | 1981-10-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1171860A true CA1171860A (en) | 1984-07-31 |
Family
ID=23203647
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000413239A Expired CA1171860A (en) | 1981-10-13 | 1982-10-12 | Oxazolidinedione derivatives |
Country Status (16)
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA832679B (en) * | 1982-05-07 | 1983-12-28 | Ici Plc | Indoline derivatives |
| EP0159143B1 (en) * | 1984-03-23 | 1987-12-16 | Pfizer Inc. | Spiro-indenes and spiro-1,2-dihydro-naphthalenes for treatment of diabetic complications |
| WO1988009661A1 (en) * | 1987-06-10 | 1988-12-15 | Pfizer Inc. | Oxazolidin-2-one derivatives as hypoglycemic agents |
| AU617541B2 (en) * | 1988-10-20 | 1991-11-28 | Wyeth | Spiro-isoquinoline-pyrrolidine tetrones and analogs thereof useful as aldose reductase inhibitors |
| US5221686A (en) * | 1992-08-04 | 1993-06-22 | American Home Products Corporation | Spiro[1,2-benzisothiazole-3(2H),5'-oxazolidine]-2',4'-dione 1,1-dioxides as antihyperglycemic agents |
| FR2708606B1 (fr) * | 1993-07-30 | 1995-10-27 | Sanofi Sa | Dérivés du N-phénylalkylindol-2-one, leur préparation, les compositions pharmaceutiques en contenant. |
| CN102336769A (zh) * | 2011-07-06 | 2012-02-01 | 华东理工大学 | 一种简便的合成螺[氧化吲哚-3,5＇-噁唑啉]杂环化合物的新方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4200642A (en) * | 1978-08-21 | 1980-04-29 | Pfizer Inc. | Spiro-oxazolidindiones |
-
1982
- 1982-09-16 ES ES515751A patent/ES8400116A1/es not_active Expired
- 1982-10-08 EP EP82305385A patent/EP0079675A1/en not_active Withdrawn
- 1982-10-11 KR KR8204569A patent/KR860000486B1/ko not_active Expired
- 1982-10-11 GR GR69495A patent/GR77019B/el unknown
- 1982-10-11 AR AR290934A patent/AR231839A1/es active
- 1982-10-11 IL IL66954A patent/IL66954A/xx unknown
- 1982-10-11 YU YU02293/82A patent/YU229382A/xx unknown
- 1982-10-12 HU HU823246A patent/HU185113B/hu unknown
- 1982-10-12 FI FI823480A patent/FI823480L/fi not_active Application Discontinuation
- 1982-10-12 PL PL23859582A patent/PL238595A1/xx unknown
- 1982-10-12 PT PT75673A patent/PT75673B/pt unknown
- 1982-10-12 AU AU89288/82A patent/AU531161B2/en not_active Ceased
- 1982-10-12 CA CA000413239A patent/CA1171860A/en not_active Expired
- 1982-10-12 PH PH27974A patent/PH18038A/en unknown
- 1982-10-12 DK DK449882A patent/DK449882A/da not_active Application Discontinuation
- 1982-10-13 JP JP57179684A patent/JPS5877883A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| AU531161B2 (en) | 1983-08-11 |
| ES515751A0 (es) | 1983-10-16 |
| KR860000486B1 (ko) | 1986-04-30 |
| FI823480A7 (fi) | 1983-04-14 |
| FI823480A0 (fi) | 1982-10-12 |
| IL66954A (en) | 1985-02-28 |
| PT75673B (en) | 1985-12-09 |
| PL238595A1 (en) | 1983-09-12 |
| DK449882A (da) | 1983-04-14 |
| JPS5877883A (ja) | 1983-05-11 |
| EP0079675A1 (en) | 1983-05-25 |
| KR840002002A (ko) | 1984-06-11 |
| PT75673A (en) | 1982-11-01 |
| AR231839A1 (es) | 1985-03-29 |
| JPS611073B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1986-01-13 |
| ES8400116A1 (es) | 1983-10-16 |
| PH18038A (en) | 1985-03-08 |
| YU229382A (en) | 1984-12-31 |
| HU185113B (en) | 1984-12-28 |
| FI823480L (fi) | 1983-04-14 |
| IL66954A0 (en) | 1983-02-23 |
| AU8928882A (en) | 1983-04-21 |
| GR77019B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1984-09-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEC | Expiry (correction) | ||
| MKEX | Expiry |