CA1165215A - Method for determining transferrine and composition therefor - Google Patents
Method for determining transferrine and composition thereforInfo
- Publication number
- CA1165215A CA1165215A CA000391654A CA391654A CA1165215A CA 1165215 A CA1165215 A CA 1165215A CA 000391654 A CA000391654 A CA 000391654A CA 391654 A CA391654 A CA 391654A CA 1165215 A CA1165215 A CA 1165215A
- Authority
- CA
- Canada
- Prior art keywords
- transferrine
- determining
- iron
- reagent
- solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title claims abstract description 31
- 239000000203 mixture Substances 0.000 title claims abstract description 13
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims abstract description 31
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 18
- 229910052742 iron Inorganic materials 0.000 claims abstract description 15
- 150000003839 salts Chemical class 0.000 claims abstract description 9
- 239000000725 suspension Substances 0.000 claims abstract description 7
- 239000006228 supernatant Substances 0.000 claims abstract description 6
- 239000007787 solid Substances 0.000 claims description 10
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 6
- 239000000758 substrate Substances 0.000 claims description 6
- OGWLTJRQYVEDMR-UHFFFAOYSA-F tetramagnesium;tetracarbonate Chemical compound [Mg+2].[Mg+2].[Mg+2].[Mg+2].[O-]C([O-])=O.[O-]C([O-])=O.[O-]C([O-])=O.[O-]C([O-])=O OGWLTJRQYVEDMR-UHFFFAOYSA-F 0.000 claims description 4
- 229940125717 barbiturate Drugs 0.000 claims description 3
- HNYOPLTXPVRDBG-UHFFFAOYSA-N barbituric acid Chemical compound O=C1CC(=O)NC(=O)N1 HNYOPLTXPVRDBG-UHFFFAOYSA-N 0.000 claims description 3
- 229910000019 calcium carbonate Inorganic materials 0.000 claims description 3
- 239000007790 solid phase Substances 0.000 claims description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims 2
- 229910019142 PO4 Inorganic materials 0.000 claims 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 claims 1
- 239000012071 phase Substances 0.000 claims 1
- 235000021317 phosphate Nutrition 0.000 claims 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 claims 1
- ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 abstract description 4
- 229910000021 magnesium carbonate Inorganic materials 0.000 abstract description 4
- 239000001095 magnesium carbonate Substances 0.000 abstract description 4
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 abstract description 2
- 102000008133 Iron-Binding Proteins Human genes 0.000 description 8
- 108010035210 Iron-Binding Proteins Proteins 0.000 description 8
- VTLYFUHAOXGGBS-UHFFFAOYSA-N Fe3+ Chemical compound [Fe+3] VTLYFUHAOXGGBS-UHFFFAOYSA-N 0.000 description 7
- 229910001447 ferric ion Inorganic materials 0.000 description 6
- 210000002966 serum Anatomy 0.000 description 6
- 238000011534 incubation Methods 0.000 description 3
- 235000014380 magnesium carbonate Nutrition 0.000 description 3
- 239000002002 slurry Substances 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 238000009738 saturating Methods 0.000 description 2
- 102000003886 Glycoproteins Human genes 0.000 description 1
- 108090000288 Glycoproteins Proteins 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 239000003929 acidic solution Substances 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 230000036765 blood level Effects 0.000 description 1
- 235000010216 calcium carbonate Nutrition 0.000 description 1
- 230000002596 correlated effect Effects 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 235000019799 monosodium phosphate Nutrition 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 1
- 229910000162 sodium phosphate Inorganic materials 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/90—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving iron binding capacity of blood
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT26564A/80 | 1980-12-11 | ||
| IT26564/80A IT1148745B (it) | 1980-12-11 | 1980-12-11 | Metodo per la determinazione della transferrina e composizione adatta allo scopo |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1165215A true CA1165215A (en) | 1984-04-10 |
Family
ID=11219789
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000391654A Expired CA1165215A (en) | 1980-12-11 | 1981-12-07 | Method for determining transferrine and composition therefor |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JPS57122361A (enExample) |
| CA (1) | CA1165215A (enExample) |
| DE (1) | DE3147538C2 (enExample) |
| ES (1) | ES508226A0 (enExample) |
| FR (1) | FR2496270A1 (enExample) |
| GB (1) | GB2089505B (enExample) |
| IT (1) | IT1148745B (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6069557A (ja) * | 1983-09-26 | 1985-04-20 | Wako Pure Chem Ind Ltd | 不飽和鉄結合能の測定方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1239121B (de) * | 1964-01-29 | 1967-04-20 | Haury Chem Fab Dr Heinz | Verfahren zur Bestimmung der totalen Eisenbindungskapazitaet von Koerperfluessigkeiten, insbesondere Serum und Urin |
| US3709985A (en) * | 1969-07-17 | 1973-01-09 | Abbott Lab | Method for determining total blood serum iron-binding capacity |
| US3996162A (en) * | 1970-02-27 | 1976-12-07 | Nuclear Medical Laboratories, Inc. | Analytical sorbent and method of use |
| JPS529160B2 (enExample) * | 1972-04-12 | 1977-03-14 | ||
| JPS5913521B2 (ja) * | 1975-06-19 | 1984-03-30 | メイトウサンギヨウ カブシキガイシヤ | 磁性酸化鉄・デキストラン複合体の製造法 |
| US4154929A (en) * | 1976-08-16 | 1979-05-15 | American Monitor Corporation | 9-(2-Pyridyl)-acenaphtho[1,2-e]-as-triazines |
-
1980
- 1980-12-11 IT IT26564/80A patent/IT1148745B/it active
-
1981
- 1981-12-01 DE DE3147538A patent/DE3147538C2/de not_active Expired
- 1981-12-07 CA CA000391654A patent/CA1165215A/en not_active Expired
- 1981-12-07 GB GB8136865A patent/GB2089505B/en not_active Expired
- 1981-12-10 FR FR8123116A patent/FR2496270A1/fr active Granted
- 1981-12-10 JP JP56197787A patent/JPS57122361A/ja active Granted
- 1981-12-10 ES ES508226A patent/ES508226A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DE3147538A1 (de) | 1982-06-24 |
| IT8026564A0 (it) | 1980-12-11 |
| ES8303698A1 (es) | 1983-02-01 |
| JPH027429B2 (enExample) | 1990-02-19 |
| GB2089505B (en) | 1984-03-21 |
| FR2496270A1 (fr) | 1982-06-18 |
| JPS57122361A (en) | 1982-07-30 |
| DE3147538C2 (de) | 1983-09-08 |
| GB2089505A (en) | 1982-06-23 |
| IT1148745B (it) | 1986-12-03 |
| ES508226A0 (es) | 1983-02-01 |
| FR2496270B1 (enExample) | 1984-03-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |