CA1163425A - Apparatus and method for the sequential performance of chemical processes - Google Patents
Apparatus and method for the sequential performance of chemical processesInfo
- Publication number
- CA1163425A CA1163425A CA000386403A CA386403A CA1163425A CA 1163425 A CA1163425 A CA 1163425A CA 000386403 A CA000386403 A CA 000386403A CA 386403 A CA386403 A CA 386403A CA 1163425 A CA1163425 A CA 1163425A
- Authority
- CA
- Canada
- Prior art keywords
- chamber
- apparatus recited
- processing apparatus
- fluids
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
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- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K7/00—Diaphragm valves or cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage ; Pinch valves
- F16K7/12—Diaphragm valves or cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage ; Pinch valves with flat, dished, or bowl-shaped diaphragm
- F16K7/14—Diaphragm valves or cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage ; Pinch valves with flat, dished, or bowl-shaped diaphragm arranged to be deformed against a flat seat
- F16K7/17—Diaphragm valves or cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage ; Pinch valves with flat, dished, or bowl-shaped diaphragm arranged to be deformed against a flat seat the diaphragm being actuated by fluid pressure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00281—Individual reactor vessels
- B01J2219/00283—Reactor vessels with top opening
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00281—Individual reactor vessels
- B01J2219/00286—Reactor vessels with top and bottom openings
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00389—Feeding through valves
- B01J2219/00396—Membrane valves
- B01J2219/00398—Membrane valves in multiple arrangements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00418—Means for dispensing and evacuation of reagents using pressure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00423—Means for dispensing and evacuation of reagents using filtration, e.g. through porous frits
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00495—Means for heating or cooling the reaction vessels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/0059—Sequential processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00596—Solid-phase processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00686—Automatic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00686—Automatic
- B01J2219/00689—Automatic using computers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00695—Synthesis control routines, e.g. using computer programs
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00725—Peptides
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1079—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices with means for piercing stoppers or septums
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Fluid Mechanics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Mechanical Engineering (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Peptides Or Proteins (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA000440138A CA1178030A (en) | 1980-09-23 | 1983-11-01 | Apparatus for the sequential performance of chemical process |
| CA000440137A CA1188197A (en) | 1980-09-23 | 1983-11-01 | Selectively controlled multiple outlet valve |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19010080A | 1980-09-23 | 1980-09-23 | |
| US190,100 | 1980-09-23 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000440138A Division CA1178030A (en) | 1980-09-23 | 1983-11-01 | Apparatus for the sequential performance of chemical process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1163425A true CA1163425A (en) | 1984-03-13 |
Family
ID=22700018
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000386403A Expired CA1163425A (en) | 1980-09-23 | 1981-09-22 | Apparatus and method for the sequential performance of chemical processes |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JPS57110962A (enrdf_load_stackoverflow) |
| CA (1) | CA1163425A (enrdf_load_stackoverflow) |
| DE (1) | DE3137875C2 (enrdf_load_stackoverflow) |
| FR (1) | FR2490505B1 (enrdf_load_stackoverflow) |
| GB (3) | GB2084899B (enrdf_load_stackoverflow) |
| SE (3) | SE466223B (enrdf_load_stackoverflow) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2544720B1 (fr) * | 1983-04-19 | 1987-11-27 | California Inst Of Techn | Installation perfectionnee et procede pour la synthese de composes chimiques, en particulier d'oligonucleotides |
| DE3425763A1 (de) * | 1983-07-13 | 1985-01-24 | Nippon Zeon Co., Ltd., Tokio/Tokyo | Verfahren zur synthese von polynukleotiden |
| JPS60105691A (ja) * | 1983-11-14 | 1985-06-11 | Nippon Zeon Co Ltd | ポリヌクレオチド合成装置 |
| CA1218930A (en) * | 1984-02-22 | 1987-03-10 | Allelix Biopharmaceuticals Inc. | Device for performing quantitative chemical and immunochemical assays |
| US4668476A (en) * | 1984-03-23 | 1987-05-26 | Applied Biosystems, Inc. | Automated polypeptide synthesis apparatus |
| DE3508162C1 (de) * | 1985-03-07 | 1986-06-19 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | Leitungssystem fuer Laboratoriumszwecke |
| DE3750624T2 (de) * | 1986-08-15 | 1995-02-16 | Beckmann Research Inst Of The | Durchlaufreaktor für Peptidsequenatoren. |
| US4773446A (en) * | 1986-08-27 | 1988-09-27 | Porton Instruments, Inc. | Valve block assembly |
| DE3637869A1 (de) * | 1986-11-06 | 1988-05-19 | Draegerwerk Ag | Mehrfachhalterung fuer pruefroehrchen |
| US5188963A (en) * | 1989-11-17 | 1993-02-23 | Gene Tec Corporation | Device for processing biological specimens for analysis of nucleic acids |
| EP0388224A3 (en) * | 1989-03-17 | 1991-05-22 | Seiko Instruments Inc. | Method and apparatus for effecting chemical treatment |
| JPH02307059A (ja) * | 1989-05-23 | 1990-12-20 | Seiko Instr Inc | 反応容器 |
| US5605839A (en) * | 1990-04-11 | 1997-02-25 | Ludwig Institute For Cancer Research | Methods and apparatus for use in sequential chemical reactions |
| DE9109797U1 (de) * | 1991-08-07 | 1991-09-26 | Wissenschaftliche Gerätebau Dr.-Ing. Herbert Knauer GmbH, 1000 Berlin | Gerät zur Durchführung von chemischen Prozessen an einer Probe eines chemischen Materials |
| IT1255014B (it) * | 1992-03-27 | 1995-10-13 | Instrumentation Lab Spa | Dispositivi di movimentazione ed intercettazione di fluidi |
| US5203368A (en) * | 1992-07-29 | 1993-04-20 | Protein Technologies Inc. | Matrix of valves |
| US5641459A (en) * | 1995-08-17 | 1997-06-24 | Pharmacia Biotech Ab | Machine for synthesizing oligonucleotides |
| DE19652823A1 (de) * | 1996-12-18 | 1998-03-26 | Guenter Prof Dr Fuhr | Strukturierter Polytetrafluorethylen-Spacer |
| GB2409411A (en) * | 2003-12-22 | 2005-06-29 | William Thomas Dennis Bates | Blood collection system |
| AU2012315883A1 (en) * | 2011-09-30 | 2014-04-17 | Ge Healthcare Limited | Reactor for multi-step radiochemistry |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3077766A (en) | 1960-07-08 | 1963-02-19 | Phillips Petroleum Co | Shut off valve for chromatographic system |
| DE1227855B (de) * | 1960-07-12 | 1966-11-03 | Ichthyol Ges | Verfahren zur Herstellung von Enzymkoerpern fuer die Durchfuehrung enzymatischer Reaktionen |
| US3717436A (en) | 1971-01-25 | 1973-02-20 | Beckman Ind Inc | Process for the sequential degradation of peptide chains |
| BE786213A (fr) * | 1971-07-13 | 1973-01-15 | Technicon Instr | Procede et appareil pour l'analyse d'echantillons, notamment desang |
| US3725010A (en) | 1971-08-23 | 1973-04-03 | Beckman Instruments Inc | Apparatus for automatically performing chemical processes |
| BE795316A (fr) * | 1972-02-11 | 1973-05-29 | Nat Patent Dev Corp | Systeme catalytique presentant une activite enzymatique durable et de stabilite augmentee |
| JPS5117438B2 (enrdf_load_stackoverflow) * | 1972-05-26 | 1976-06-02 | ||
| GB1427192A (en) * | 1972-05-26 | 1976-03-10 | Kannegiesser M | Apparatus for manufacturing mouldings from expandable synthetic plastics more particularly polyurethane |
| DE2308088C2 (de) * | 1973-02-19 | 1983-03-17 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | Verfahren zur automatisierten Bestimmung der Aminosäuresequenz und Vorrichtung zu ihrer Durchführung |
| US3892531A (en) * | 1973-07-05 | 1975-07-01 | Beckman Instruments Inc | Apparatus for sequencing peptides and proteins |
| US3959307A (en) | 1974-02-15 | 1976-05-25 | Wittmann Brigitte | Method to determine automatically the sequence of amino acids |
| US3951167A (en) | 1974-12-05 | 1976-04-20 | E. I. Du Pont De Nemours And Company | Fluid handling assembly |
| US4065412A (en) * | 1976-05-07 | 1977-12-27 | Durrum Instrument Corporation | Peptide or protein sequencing method and apparatus |
| US4119120A (en) | 1976-11-29 | 1978-10-10 | Beckman Instruments, Inc. | Fluid switch |
| US4252769A (en) * | 1979-12-26 | 1981-02-24 | California Institute Of Technology | Apparatus for the performance of chemical processes |
-
1981
- 1981-09-10 GB GB8127343A patent/GB2084899B/en not_active Expired
- 1981-09-22 FR FR8117856A patent/FR2490505B1/fr not_active Expired
- 1981-09-22 CA CA000386403A patent/CA1163425A/en not_active Expired
- 1981-09-22 JP JP14890381A patent/JPS57110962A/ja active Granted
- 1981-09-22 SE SE8105597A patent/SE466223B/sv not_active IP Right Cessation
- 1981-09-23 DE DE19813137875 patent/DE3137875C2/de not_active Expired - Lifetime
-
1983
- 1983-12-14 GB GB08333305A patent/GB2146741B/en not_active Expired
- 1983-12-14 GB GB08333306A patent/GB2146550B/en not_active Expired
-
1988
- 1988-06-07 SE SE8802124A patent/SE501968C2/sv not_active IP Right Cessation
- 1988-06-07 SE SE8802125A patent/SE8802125A0/sv not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| GB2084899A (en) | 1982-04-21 |
| JPH0256635B2 (enrdf_load_stackoverflow) | 1990-11-30 |
| SE501968C2 (sv) | 1995-07-03 |
| GB2146741B (en) | 1985-11-20 |
| SE466223B (sv) | 1992-01-13 |
| GB8333305D0 (en) | 1984-01-18 |
| GB8333306D0 (en) | 1984-01-18 |
| DE3137875A1 (de) | 1982-05-06 |
| DE3137875C2 (de) | 1995-11-02 |
| SE8802125D0 (sv) | 1988-06-07 |
| FR2490505B1 (fr) | 1986-01-03 |
| GB2146550A (en) | 1985-04-24 |
| SE8802124D0 (sv) | 1988-06-07 |
| SE8802124L (enrdf_load_stackoverflow) | 1988-06-07 |
| FR2490505A1 (fr) | 1982-03-26 |
| GB2146550B (en) | 1985-11-13 |
| GB2146741A (en) | 1985-04-24 |
| SE8802125A0 (sv) | 1988-06-07 |
| SE8105597L (sv) | 1982-05-06 |
| JPS57110962A (en) | 1982-07-10 |
| GB2084899B (en) | 1985-05-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |