CA1162868A - Process for preparing insulin esters - Google Patents

Process for preparing insulin esters

Info

Publication number
CA1162868A
CA1162868A CA000370483A CA370483A CA1162868A CA 1162868 A CA1162868 A CA 1162868A CA 000370483 A CA000370483 A CA 000370483A CA 370483 A CA370483 A CA 370483A CA 1162868 A CA1162868 A CA 1162868A
Authority
CA
Canada
Prior art keywords
process according
insulin
thr
porcine
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000370483A
Other languages
English (en)
French (fr)
Inventor
Jan Markussen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Industri AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8095095&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA1162868(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novo Industri AS filed Critical Novo Industri AS
Application granted granted Critical
Publication of CA1162868A publication Critical patent/CA1162868A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Forklifts And Lifting Vehicles (AREA)
CA000370483A 1980-02-11 1981-02-10 Process for preparing insulin esters Expired CA1162868A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK80.574 1980-02-11
DK57480A DK147109C (da) 1980-02-11 1980-02-11 Fremgangsmaade til fremstilling af humant insulin eller humane insulinestere eller et salt eller kompleks deraf

Publications (1)

Publication Number Publication Date
CA1162868A true CA1162868A (en) 1984-02-28

Family

ID=8095095

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000370483A Expired CA1162868A (en) 1980-02-11 1981-02-10 Process for preparing insulin esters

Country Status (19)

Country Link
JP (1) JPS56135452A (sv)
AR (1) AR231277A1 (sv)
AU (1) AU541528B2 (sv)
BE (1) BE887480A (sv)
CA (1) CA1162868A (sv)
CH (1) CH655949A5 (sv)
DE (1) DE3104949C2 (sv)
DK (3) DK147109C (sv)
ES (1) ES8205858A1 (sv)
FI (1) FI77876C (sv)
GB (1) GB2069502B (sv)
GR (1) GR73844B (sv)
IT (1) IT1195038B (sv)
NL (1) NL178797C (sv)
NO (1) NO156247C (sv)
NZ (1) NZ196224A (sv)
PT (1) PT72485B (sv)
SE (2) SE427025B (sv)
ZA (1) ZA81898B (sv)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK147437A (en) 1980-02-11 1900-01-01 Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
DE3101382A1 (de) * 1981-01-17 1982-09-02 Hoechst Ag, 6000 Frankfurt "verfahren zur herstellung von humanisulin oder dessen derivaten aus schweineinsulin oder dessen derivaten"
CA1174623A (en) * 1981-09-15 1984-09-18 Finn H. Andresen Process for preparing human insulin or b-30 esters thereof
DK149824C (da) * 1982-01-22 1987-03-16 Carlsberg Biotechnology Ltd Fremgangsmaade til enzymatisk udskiftning af b-30 aminosyrer i insuliner
EP0087238A1 (en) * 1982-02-08 1983-08-31 Biogen N.V. Am improved method for preparing human insulin from non-human insulin
DE3209184A1 (de) * 1982-03-13 1983-09-15 Hoechst Ag, 6230 Frankfurt Verfahren zur umwandlung von praeproinsulinanaloga zu insulinen
NL8201650A (nl) * 1982-04-21 1983-11-16 Akzo Nv Semisynthetische bereiding van humane insuline.
DK182483A (da) * 1982-04-23 1983-10-24 Wako Pure Chem Ind Ltd Fremgangsmaade til semi-syntese af humant insulin og alkalisk protease til anvendelse derved
DK55183D0 (da) * 1983-02-09 1983-02-09 Nordisk Insulinlab Fremgangsmade til fremstilling af human insulin
DE3334407A1 (de) * 1983-09-23 1985-04-04 Hoechst Ag, 6230 Frankfurt In position b 30 modifizierte insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus
DK119785D0 (da) * 1985-03-15 1985-03-15 Nordisk Gentofte Insulinpraeparat
US5157021A (en) * 1985-03-15 1992-10-20 Novo Nordisk A/S Insulin derivatives and pharmaceutical preparations containing these derivatives
SE449472B (sv) * 1985-10-15 1987-05-04 Mth Gruppen Ab Utrustning vid facklager
EP0280534B1 (en) * 1987-02-25 1993-04-21 Novo Nordisk A/S Novel insulin derivatives
DK134189D0 (da) * 1989-03-20 1989-03-20 Nordisk Gentofte Insulinforbindelser
FI96503C (sv) * 1994-08-26 1996-07-10 Hymatic Ltd Oy Metod och apparatur för styrning av en mast
JP4601627B2 (ja) 2004-01-16 2010-12-22 バイオデル， インコーポレイテッド 舌下薬物送達デバイス
US20080090753A1 (en) 2004-03-12 2008-04-17 Biodel, Inc. Rapid Acting Injectable Insulin Compositions
US7713929B2 (en) 2006-04-12 2010-05-11 Biodel Inc. Rapid acting and long acting insulin combination formulations
US8084420B2 (en) 2005-09-29 2011-12-27 Biodel Inc. Rapid acting and long acting insulin combination formulations
CA2649109A1 (en) 2006-04-12 2007-10-25 Biodel, Inc. Rapid acting and long acting insulin combination formulations
US9060927B2 (en) 2009-03-03 2015-06-23 Biodel Inc. Insulin formulations for rapid uptake

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0017938B1 (en) * 1979-04-13 1983-08-03 Shionogi & Co., Ltd. Process for preparing a b30-threonine insulin
DK147437A (en) 1980-02-11 1900-01-01 Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
DE3101382A1 (de) * 1981-01-17 1982-09-02 Hoechst Ag, 6000 Frankfurt "verfahren zur herstellung von humanisulin oder dessen derivaten aus schweineinsulin oder dessen derivaten"

Also Published As

Publication number Publication date
DK147437A (en) 1900-01-01
DK147109C (da) 1986-12-08
NL178797C (nl) 1986-05-16
DE3104949A1 (de) 1981-11-26
PT72485B (en) 1982-10-14
NL178797B (nl) 1985-12-16
GB2069502A (en) 1981-08-26
PT72485A (en) 1981-03-01
NO810443L (no) 1981-08-12
DK54081A (da) 1981-08-12
BE887480A (fr) 1981-08-11
GR73844B (sv) 1984-05-07
DE3104949C2 (de) 1984-04-26
NO156247B (no) 1987-05-11
JPH0211240B2 (sv) 1990-03-13
SE451143B (sv) 1987-09-07
ZA81898B (en) 1982-03-31
IT1195038B (it) 1988-09-28
IT8119620A1 (it) 1982-08-10
ES499238A0 (es) 1982-08-01
AU6718081A (en) 1981-08-20
SE8100926L (sv) 1982-08-11
NO156247C (no) 1987-08-19
NL8100624A (nl) 1981-09-01
ES8205858A1 (es) 1982-08-01
SE427025B (sv) 1983-02-28
GB2069502B (en) 1984-08-08
DK57480A (da) 1981-08-12
FI77876C (sv) 1989-05-10
NZ196224A (en) 1984-08-24
CH655949A5 (de) 1986-05-30
SE8100928L (sv) 1981-08-12
JPS56135452A (en) 1981-10-22
DK147437B (da) 1984-08-06
DK147109B (da) 1984-04-09
AU541528B2 (en) 1985-01-10
FI810385L (fi) 1981-08-12
IT8119620A0 (it) 1981-02-10
DK147437C (da) 1986-12-08
AR231277A1 (es) 1984-10-31
FI77876B (fi) 1989-01-31

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US5157021A (en) Insulin derivatives and pharmaceutical preparations containing these derivatives
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KR880001107B1 (ko) 인체 인슐린 및 그의 유도체의 제조방법
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Legal Events

Date Code Title Description
MKEX Expiry