CA1153763A - 1(2h)-isoquinolone compounds and acid addition salts thereof - Google Patents

1(2h)-isoquinolone compounds and acid addition salts thereof

Info

Publication number
CA1153763A
CA1153763A CA000358717A CA358717A CA1153763A CA 1153763 A CA1153763 A CA 1153763A CA 000358717 A CA000358717 A CA 000358717A CA 358717 A CA358717 A CA 358717A CA 1153763 A CA1153763 A CA 1153763A
Authority
CA
Canada
Prior art keywords
group
isoquinolone
formula
addition salts
acid addition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000358717A
Other languages
English (en)
French (fr)
Inventor
Shigeo Senda
Osamu Ohtani
Eiichi Katho
Hidekazu Miyake
Khosuke Fujiwara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Maruko Pharmaceutical Co Ltd
Taiho Pharmaceutical Co Ltd
Original Assignee
Maruko Pharmaceutical Co Ltd
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Maruko Pharmaceutical Co Ltd, Taiho Pharmaceutical Co Ltd filed Critical Maruko Pharmaceutical Co Ltd
Application granted granted Critical
Publication of CA1153763A publication Critical patent/CA1153763A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA000358717A 1979-08-21 1980-08-21 1(2h)-isoquinolone compounds and acid addition salts thereof Expired CA1153763A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10549779A JPS5677261A (en) 1979-08-21 1979-08-21 1 2h isoquinolone derivative and its acid addition salt
JP105497/79 1979-08-21

Publications (1)

Publication Number Publication Date
CA1153763A true CA1153763A (en) 1983-09-13

Family

ID=14409228

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000358717A Expired CA1153763A (en) 1979-08-21 1980-08-21 1(2h)-isoquinolone compounds and acid addition salts thereof

Country Status (10)

Country Link
JP (1) JPS5677261A (de)
AU (1) AU532023B2 (de)
CA (1) CA1153763A (de)
CH (1) CH646953A5 (de)
DE (1) DE3031574A1 (de)
ES (1) ES494891A0 (de)
FR (1) FR2463766A1 (de)
GB (1) GB2058783B (de)
IT (1) IT1188988B (de)
NL (1) NL8004736A (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2098980B (en) * 1981-03-28 1985-05-15 Taiho Pharmaceutical Co Ltd 1(2h)-isoquinolone compounds and acid addition salts thereof
JPS58164577A (ja) * 1982-03-24 1983-09-29 Taiho Yakuhin Kogyo Kk ４―ベンジル―１―（２ｈ）イソキノロン誘導体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3600394A (en) * 1968-05-17 1971-08-17 Searle & Co 2-aminoalkyl-3-arylisocarbostyrils
SE368009B (de) * 1971-09-16 1974-06-17 Kabi Ab
US3928612A (en) * 1974-10-02 1975-12-23 American Home Prod 1,2-Dihydro- and 1,2,3,4-tetrahydro-1-oxo-3-isoquinolinecarboxylic acid derivatives as anti-allergic agents

Also Published As

Publication number Publication date
ES8106501A1 (es) 1981-09-01
GB2058783A (en) 1981-04-15
FR2463766A1 (fr) 1981-02-27
CH646953A5 (de) 1984-12-28
AU532023B2 (en) 1983-09-15
IT1188988B (it) 1988-01-28
IT8049519A1 (it) 1982-02-19
AU6160980A (en) 1981-04-09
GB2058783B (en) 1983-04-07
IT8049519A0 (it) 1980-08-19
ES494891A0 (es) 1981-09-01
NL8004736A (nl) 1981-02-24
FR2463766B1 (de) 1983-09-02
DE3031574A1 (de) 1981-03-12
JPS5677261A (en) 1981-06-25

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Legal Events

Date Code Title Description
MKEX Expiry