CA1142943A - 4-guanidinomethylcyclohexane carboxylic acid compounds - Google Patents

4-guanidinomethylcyclohexane carboxylic acid compounds

Info

Publication number
CA1142943A
CA1142943A CA000360655A CA360655A CA1142943A CA 1142943 A CA1142943 A CA 1142943A CA 000360655 A CA000360655 A CA 000360655A CA 360655 A CA360655 A CA 360655A CA 1142943 A CA1142943 A CA 1142943A
Authority
CA
Canada
Prior art keywords
group
formula
compound
trans
hydrochloride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000360655A
Other languages
English (en)
French (fr)
Inventor
Mutsumi Muramatsu
Toshio Satoh
Yukio Yanagimoto
Tadami Shinuchi
Toshio Nakajima
Isao Nakajima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Chemiphar Co Ltd
Teikoku Chemical Industry Co Ltd
Original Assignee
Nippon Chemiphar Co Ltd
Teikoku Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP12014279A external-priority patent/JPS5645454A/ja
Priority claimed from JP16827179A external-priority patent/JPS5692260A/ja
Priority claimed from JP16827279A external-priority patent/JPS5692261A/ja
Application filed by Nippon Chemiphar Co Ltd, Teikoku Chemical Industry Co Ltd filed Critical Nippon Chemiphar Co Ltd
Application granted granted Critical
Publication of CA1142943A publication Critical patent/CA1142943A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/65One oxygen atom attached in position 3 or 5

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
CA000360655A 1979-09-20 1980-09-19 4-guanidinomethylcyclohexane carboxylic acid compounds Expired CA1142943A (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP54-120142 1979-09-20
JP12014279A JPS5645454A (en) 1979-09-20 1979-09-20 Cyclohexanecarboxylic acid derivative and its preparation
JP54-168271 1979-12-26
JP16827179A JPS5692260A (en) 1979-12-26 1979-12-26 Cyclohexanecarboxylic ester and its preparation
JP16827279A JPS5692261A (en) 1979-12-26 1979-12-26 Novel cyclohexanecarboxylic derivative and its preparation
JP54-168272 1979-12-26

Publications (1)

Publication Number Publication Date
CA1142943A true CA1142943A (en) 1983-03-15

Family

ID=27313978

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000360655A Expired CA1142943A (en) 1979-09-20 1980-09-19 4-guanidinomethylcyclohexane carboxylic acid compounds

Country Status (17)

Country Link
US (1) US4348410A (en, 2012)
AR (1) AR227525A1 (en, 2012)
AT (1) AT375918B (en, 2012)
AU (1) AU541738B2 (en, 2012)
BR (1) BR8006052A (en, 2012)
CA (1) CA1142943A (en, 2012)
CH (1) CH646687A5 (en, 2012)
DE (1) DE3035086A1 (en, 2012)
DK (1) DK163580C (en, 2012)
ES (1) ES495175A0 (en, 2012)
FR (1) FR2472561B1 (en, 2012)
GB (1) GB2058773B (en, 2012)
IN (1) IN151297B (en, 2012)
IT (1) IT1129264B (en, 2012)
NL (1) NL8005238A (en, 2012)
PH (1) PH17322A (en, 2012)
SE (1) SE460667B (en, 2012)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4465851A (en) * 1981-01-22 1984-08-14 Nippon Chemiphar Co., Ltd. Guanidinocyclohexanecarboxylic acid derivatives
JPS5838250A (ja) * 1981-09-01 1983-03-05 Teikoku Chem Ind Corp Ltd 複合体
JPS6254A (ja) * 1985-03-08 1987-01-06 Kanebo Ltd 新規グアニジノメチルシクロヘキサンカルボン酸誘導体および該化合物を有効成分とする抗潰瘍薬
JPS6229566A (ja) * 1985-07-30 1987-02-07 Taiyo Yakuhin Kogyo Kk 新規グアニジノメチル安息香酸誘導体
KR100404714B1 (ko) * 1994-08-30 2004-05-31 데이코쿠 가가꾸 산교 가부시키가이샤 구아니디노메틸사이클로헥산카복실산에스테르유도체
JP4191269B2 (ja) 1996-05-17 2008-12-03 興和株式会社 新規なアニリド化合物及びこれを含有する医薬
BR9908911A (pt) 1998-03-19 2001-10-02 Bristol Myers Squibb Co Sistema bifásico e processo de distribuição por liberação controlada de substâncias farmacêuticas de alta solubilidade
ES2219607T3 (es) 1998-07-20 2004-12-01 Wilex Ag Nuevo agente inhibidor de la urocinasa.
US7342018B2 (en) 1998-07-20 2008-03-11 Wilex Ag Urokinase inhibitors and uses thereof
CN1203055C (zh) 2001-09-26 2005-05-25 朱德煦 治疗或预防细菌感染的方法和组合物
US20070134231A1 (en) * 2005-12-13 2007-06-14 Jani Dharmendra M Method for prolonging activity of autodegradable enzymes and compositions thereof
KR101942590B1 (ko) 2010-07-09 2019-01-25 비에이치브이 파르마, 인크. 레모글리플로진을 포함하는 짧은 반감기 약제용의 즉시/지연 조합 방출 전달 시스템
GB2541910B (en) 2015-09-03 2021-10-27 Thermographic Measurements Ltd Thermochromic composition
JP7380693B2 (ja) * 2018-10-22 2023-11-15 キーケルト アクツィーエンゲゼルシャフト 自動車用ロック

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5913498B2 (ja) * 1975-07-30 1984-03-30 第一製薬株式会社 トランス−4−アミノメチルシクロヘキサンカルボン酸エステルの製法
US4147876A (en) * 1978-05-01 1979-04-03 Daiichi Seiyaku Co., Ltd. Easily hydrolyzable esters of 4-(2-carboxyethyl)phenyl trans-4-aminomethylcyclohexanecarboxylate and process of use

Also Published As

Publication number Publication date
IT1129264B (it) 1986-06-04
GB2058773A (en) 1981-04-15
PH17322A (en) 1984-07-20
AU6232080A (en) 1981-03-26
DE3035086A1 (de) 1981-04-09
ES8200643A1 (es) 1981-10-16
US4348410A (en) 1982-09-07
DK396880A (da) 1981-03-21
FR2472561A1 (fr) 1981-07-03
IN151297B (en, 2012) 1983-03-26
ES495175A0 (es) 1981-10-16
GB2058773B (en) 1983-03-23
BR8006052A (pt) 1981-04-07
CH646687A5 (fr) 1984-12-14
ATA470680A (de) 1984-02-15
SE460667B (sv) 1989-11-06
NL8005238A (nl) 1981-03-24
AR227525A1 (es) 1982-11-15
IT8068457A0 (it) 1980-09-19
AT375918B (de) 1984-09-25
FR2472561B1 (fr) 1985-05-31
DE3035086C2 (en, 2012) 1991-01-03
DK163580B (da) 1992-03-16
DK163580C (da) 1992-08-03
SE8006365L (sv) 1981-03-21
AU541738B2 (en) 1985-01-17

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Legal Events

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