CA1128038A - Procede de bromation d'alcaloides d'ergot - Google Patents

Procede de bromation d'alcaloides d'ergot

Info

Publication number
CA1128038A
CA1128038A CA336,448A CA336448A CA1128038A CA 1128038 A CA1128038 A CA 1128038A CA 336448 A CA336448 A CA 336448A CA 1128038 A CA1128038 A CA 1128038A
Authority
CA
Canada
Prior art keywords
alkyl
bromo
methyl
chloro
amido
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA336,448A
Other languages
English (en)
Inventor
Milan Jurgec
Branko Stanovnik
Rudolf Rucman
Miha Tisler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Application granted granted Critical
Publication of CA1128038A publication Critical patent/CA1128038A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA336,448A 1978-09-26 1979-09-26 Procede de bromation d'alcaloides d'ergot Expired CA1128038A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
YUP2268/78 1978-09-26
YU2268/78A YU39849B (en) 1978-09-26 1978-09-26 Process for preparing 2-bromo-ergolene and 2-bromo-ergoline compounds

Publications (1)

Publication Number Publication Date
CA1128038A true CA1128038A (fr) 1982-07-20

Family

ID=25557457

Family Applications (1)

Application Number Title Priority Date Filing Date
CA336,448A Expired CA1128038A (fr) 1978-09-26 1979-09-26 Procede de bromation d'alcaloides d'ergot

Country Status (45)

Country Link
JP (1) JPS5545699A (fr)
AR (1) AR223496A1 (fr)
AT (1) AT376439B (fr)
AU (1) AU529462B2 (fr)
BE (1) BE878953A (fr)
BG (1) BG32716A3 (fr)
BR (1) BR7906175A (fr)
CA (1) CA1128038A (fr)
CH (1) CH649769A5 (fr)
CS (1) CS215027B2 (fr)
CY (1) CY1240A (fr)
DD (1) DD146048A5 (fr)
DE (1) DE2938313A1 (fr)
DK (1) DK149956C (fr)
EG (1) EG14277A (fr)
ES (1) ES484445A1 (fr)
FI (1) FI66185C (fr)
FR (1) FR2437411A1 (fr)
GB (1) GB2031890B (fr)
GR (1) GR73015B (fr)
HK (1) HK49184A (fr)
HU (1) HU182576B (fr)
IE (1) IE49076B1 (fr)
IL (1) IL58318A (fr)
IN (1) IN154914B (fr)
IS (1) IS2512A7 (fr)
IT (1) IT1206988B (fr)
KE (1) KE3392A (fr)
LU (1) LU81714A1 (fr)
MA (1) MA18595A1 (fr)
MX (1) MX5864E (fr)
MY (1) MY8500131A (fr)
NL (1) NL7907122A (fr)
NO (1) NO153852C (fr)
NZ (1) NZ191643A (fr)
PH (1) PH14986A (fr)
PL (1) PL120388B1 (fr)
PT (1) PT70216A (fr)
RO (1) RO78936A (fr)
SE (1) SE433497B (fr)
SG (1) SG20484G (fr)
SU (1) SU1178324A3 (fr)
UA (1) UA7078A1 (fr)
YU (1) YU39849B (fr)
ZA (1) ZA795110B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU196394B (en) * 1986-06-27 1988-11-28 Richter Gedeon Vegyeszet Process for preparing 2-halogenated ergoline derivatives
CN104016982A (zh) * 2014-06-26 2014-09-03 华东理工大学 一种利用大孔树脂制备烟曲霉文丙的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH507249A (de) * 1968-05-31 1971-05-15 Sandoz Ag Verfahren zur Herstellung von 2-Brom-a-ergokryptin
YU39786B (en) * 1976-12-23 1985-04-30 Lek Tovarna Farmacevtskih Process for preparing 2-bromo-alfa-ergocriptine
YU216177A (en) * 1977-09-09 1984-02-29 Rudolf Rucman Process for preparing 2-bromo ergosine

Also Published As

Publication number Publication date
FR2437411A1 (fr) 1980-04-25
JPS6239158B2 (fr) 1987-08-21
IS1161B6 (is) 1984-05-10
AU5117279A (en) 1980-04-03
BE878953A (fr) 1980-03-24
IE791832L (en) 1980-03-26
ATA624379A (de) 1984-04-15
YU226878A (en) 1983-01-21
IN154914B (fr) 1984-12-22
DK149956B (da) 1986-11-03
RO78936A (fr) 1982-07-06
NO153852C (no) 1986-06-04
KE3392A (en) 1984-06-08
IT1206988B (it) 1989-05-17
SU1178324A3 (ru) 1985-09-07
CY1240A (en) 1984-06-29
EG14277A (en) 1990-06-30
NZ191643A (en) 1982-05-25
HK49184A (en) 1984-06-22
UA7078A1 (uk) 1995-06-30
DE2938313C2 (fr) 1988-07-07
BG32716A3 (en) 1982-09-15
AU529462B2 (en) 1983-06-09
IE49076B1 (en) 1985-07-24
YU39849B (en) 1985-04-30
NO793058L (no) 1980-03-27
IL58318A0 (en) 1979-12-30
DE2938313A1 (de) 1980-04-10
JPS5545699A (en) 1980-03-31
NL7907122A (nl) 1980-03-28
FI66185C (fi) 1984-09-10
CH649769A5 (de) 1985-06-14
MX5864E (es) 1984-08-13
IS2512A7 (is) 1988-03-27
MA18595A1 (fr) 1980-04-01
DK401979A (da) 1980-03-27
AR223496A1 (es) 1981-08-31
NO153852B (no) 1986-02-24
DK149956C (da) 1987-05-18
BR7906175A (pt) 1980-05-27
SE433497B (sv) 1984-05-28
FR2437411B1 (fr) 1983-03-18
CS215027B2 (en) 1982-06-25
ES484445A1 (es) 1980-09-01
IL58318A (en) 1982-07-30
PL120388B1 (en) 1982-02-27
LU81714A1 (fr) 1980-04-21
GB2031890A (en) 1980-04-30
SE7907942L (sv) 1980-03-27
PL218497A1 (fr) 1980-07-14
ZA795110B (en) 1981-05-27
PT70216A (en) 1979-10-01
PH14986A (en) 1982-03-05
FI66185B (fi) 1984-05-31
FI792957A (fi) 1980-03-27
DD146048A5 (de) 1981-01-21
GB2031890B (en) 1983-02-02
SG20484G (en) 1985-03-08
IT7950300A0 (it) 1979-09-19
MY8500131A (en) 1985-12-31
AT376439B (de) 1984-11-26
GR73015B (fr) 1984-01-25
HU182576B (en) 1984-02-28

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Legal Events

Date Code Title Description
MKEX Expiry