CA1122889A - Reduction of detectable species migration in elements for the analysis of liquids - Google Patents
Reduction of detectable species migration in elements for the analysis of liquidsInfo
- Publication number
- CA1122889A CA1122889A CA308,805A CA308805A CA1122889A CA 1122889 A CA1122889 A CA 1122889A CA 308805 A CA308805 A CA 308805A CA 1122889 A CA1122889 A CA 1122889A
- Authority
- CA
- Canada
- Prior art keywords
- layer
- radiation
- dye
- analyte
- permeable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000005012 migration Effects 0.000 title claims abstract description 35
- 238000013508 migration Methods 0.000 title claims abstract description 35
- 238000004458 analytical method Methods 0.000 title claims abstract description 29
- 239000007788 liquid Substances 0.000 title claims abstract description 26
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 82
- 239000012491 analyte Substances 0.000 claims abstract description 46
- 230000007480 spreading Effects 0.000 claims abstract description 42
- 230000002401 inhibitory effect Effects 0.000 claims abstract description 36
- 239000000203 mixture Substances 0.000 claims abstract description 14
- 229920000642 polymer Polymers 0.000 claims description 13
- 230000002452 interceptive effect Effects 0.000 claims description 11
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 10
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 10
- 239000011575 calcium Substances 0.000 claims description 10
- 229910052791 calcium Inorganic materials 0.000 claims description 10
- 239000008103 glucose Substances 0.000 claims description 10
- 239000000178 monomer Substances 0.000 claims description 7
- 239000000084 colloidal system Substances 0.000 claims description 6
- 125000000217 alkyl group Chemical group 0.000 claims description 5
- 125000003710 aryl alkyl group Chemical group 0.000 claims description 5
- 125000003118 aryl group Chemical group 0.000 claims description 5
- 230000015572 biosynthetic process Effects 0.000 claims description 5
- 125000004432 carbon atom Chemical group C* 0.000 claims description 5
- 125000003342 alkenyl group Chemical group 0.000 claims description 4
- 150000001450 anions Chemical class 0.000 claims description 4
- 125000004429 atom Chemical group 0.000 claims description 4
- 230000000694 effects Effects 0.000 claims description 4
- 239000000049 pigment Substances 0.000 claims description 4
- 102000003992 Peroxidases Human genes 0.000 claims description 3
- 239000002253 acid Substances 0.000 claims description 3
- 125000002091 cationic group Chemical group 0.000 claims description 3
- 150000001875 compounds Chemical class 0.000 claims description 3
- 125000000623 heterocyclic group Chemical group 0.000 claims description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 claims description 2
- 230000002209 hydrophobic effect Effects 0.000 claims description 2
- 125000005647 linker group Chemical group 0.000 claims description 2
- 108040007629 peroxidase activity proteins Proteins 0.000 claims description 2
- XYFCBTPGUUZFHI-UHFFFAOYSA-O phosphonium Chemical compound [PH4+] XYFCBTPGUUZFHI-UHFFFAOYSA-O 0.000 claims description 2
- 241000894007 species Species 0.000 claims 10
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims 2
- 108010015776 Glucose oxidase Proteins 0.000 claims 1
- 239000004366 Glucose oxidase Substances 0.000 claims 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 1
- 229910052729 chemical element Inorganic materials 0.000 claims 1
- 229940116332 glucose oxidase Drugs 0.000 claims 1
- 235000019420 glucose oxidase Nutrition 0.000 claims 1
- 108010046301 glucose peroxidase Proteins 0.000 claims 1
- 229910052717 sulfur Inorganic materials 0.000 claims 1
- 239000011593 sulfur Substances 0.000 claims 1
- 230000003287 optical effect Effects 0.000 abstract description 3
- 239000010410 layer Substances 0.000 description 220
- 239000000523 sample Substances 0.000 description 10
- 239000000463 material Substances 0.000 description 8
- 230000005855 radiation Effects 0.000 description 7
- MYRTYDVEIRVNKP-UHFFFAOYSA-N 1,2-Divinylbenzene Chemical compound C=CC1=CC=CC=C1C=C MYRTYDVEIRVNKP-UHFFFAOYSA-N 0.000 description 6
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 description 6
- 238000005259 measurement Methods 0.000 description 6
- -1 poly(vinyl pyrrolidone) Polymers 0.000 description 6
- 108010010803 Gelatin Proteins 0.000 description 5
- 238000006243 chemical reaction Methods 0.000 description 5
- 239000007795 chemical reaction product Substances 0.000 description 5
- 229920000159 gelatin Polymers 0.000 description 5
- 239000008273 gelatin Substances 0.000 description 5
- 235000019322 gelatine Nutrition 0.000 description 5
- 235000011852 gelatine desserts Nutrition 0.000 description 5
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 4
- 229920002301 cellulose acetate Polymers 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 4
- 229920001577 copolymer Polymers 0.000 description 3
- 238000001514 detection method Methods 0.000 description 3
- 230000035945 sensitivity Effects 0.000 description 3
- QLAJNZSPVITUCQ-UHFFFAOYSA-N 1,3,2-dioxathietane 2,2-dioxide Chemical compound O=S1(=O)OCO1 QLAJNZSPVITUCQ-UHFFFAOYSA-N 0.000 description 2
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 239000013068 control sample Substances 0.000 description 2
- 235000019441 ethanol Nutrition 0.000 description 2
- 125000005842 heteroatom Chemical group 0.000 description 2
- 230000003993 interaction Effects 0.000 description 2
- QNILTEGFHQSKFF-UHFFFAOYSA-N n-propan-2-ylprop-2-enamide Chemical compound CC(C)NC(=O)C=C QNILTEGFHQSKFF-UHFFFAOYSA-N 0.000 description 2
- 239000002674 ointment Substances 0.000 description 2
- 230000036961 partial effect Effects 0.000 description 2
- 239000011236 particulate material Substances 0.000 description 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 2
- 230000002829 reductive effect Effects 0.000 description 2
- 238000002798 spectrophotometry method Methods 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- AYWKNYLMBKCHIO-UHFFFAOYSA-M (2-ethenoxy-2-oxoethyl)-trimethylazanium;chloride Chemical compound [Cl-].C[N+](C)(C)CC(=O)OC=C AYWKNYLMBKCHIO-UHFFFAOYSA-M 0.000 description 1
- KAMCBFNNGGVPPW-UHFFFAOYSA-N 1-(ethenylsulfonylmethoxymethylsulfonyl)ethene Chemical compound C=CS(=O)(=O)COCS(=O)(=O)C=C KAMCBFNNGGVPPW-UHFFFAOYSA-N 0.000 description 1
- SBAPKYXYDFVHKP-UHFFFAOYSA-N 2,7-dimethylocta-2,6-dienedioic acid Chemical compound OC(=O)C(C)=CCCC=C(C)C(O)=O SBAPKYXYDFVHKP-UHFFFAOYSA-N 0.000 description 1
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 description 1
- DUHQIGLHYXLKAE-UHFFFAOYSA-N 3,3-dimethylglutaric acid Chemical compound OC(=O)CC(C)(C)CC(O)=O DUHQIGLHYXLKAE-UHFFFAOYSA-N 0.000 description 1
- LMBABJNSZGKTBA-UHFFFAOYSA-N 3,6-bis[(4-chloro-2-phosphonophenyl)diazenyl]-4,5-dihydroxynaphthalene-2,7-disulfonic acid Chemical compound OS(=O)(=O)C1=CC2=CC(S(O)(=O)=O)=C(N=NC=3C(=CC(Cl)=CC=3)P(O)(O)=O)C(O)=C2C(O)=C1N=NC1=CC=C(Cl)C=C1P(O)(O)=O LMBABJNSZGKTBA-UHFFFAOYSA-N 0.000 description 1
- WSSUAOUTIGITAL-UHFFFAOYSA-M 3-(2,5-dioxopyrrol-1-yl)propyl-trimethylazanium;chloride Chemical compound [Cl-].C[N+](C)(C)CCCN1C(=O)C=CC1=O WSSUAOUTIGITAL-UHFFFAOYSA-M 0.000 description 1
- HMNBKPJLCVHWRW-UHFFFAOYSA-N 5-ethenyl-1,2-dimethylpyridin-1-ium Chemical compound CC1=CC=C(C=C)C=[N+]1C HMNBKPJLCVHWRW-UHFFFAOYSA-N 0.000 description 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
- 229920000936 Agarose Polymers 0.000 description 1
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- BAVYZALUXZFZLV-UHFFFAOYSA-O Methylammonium ion Chemical compound [NH3+]C BAVYZALUXZFZLV-UHFFFAOYSA-O 0.000 description 1
- 102000004316 Oxidoreductases Human genes 0.000 description 1
- 108090000854 Oxidoreductases Proteins 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 1
- LOPVAWVHGAWUPS-UHFFFAOYSA-M [2-hydroxy-3-(2-methylprop-2-enoyloxy)propyl]-trimethylazanium;chloride Chemical compound [Cl-].CC(=C)C(=O)OCC(O)C[N+](C)(C)C LOPVAWVHGAWUPS-UHFFFAOYSA-M 0.000 description 1
- 150000003926 acrylamides Chemical class 0.000 description 1
- 125000005250 alkyl acrylate group Chemical group 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 description 1
- QCEQORGPXYFBDK-UHFFFAOYSA-M benzyl-dimethyl-(1-phenylprop-2-enyl)azanium;chloride Chemical compound [Cl-].C=1C=CC=CC=1C(C=C)[N+](C)(C)CC1=CC=CC=C1 QCEQORGPXYFBDK-UHFFFAOYSA-M 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 230000003197 catalytic effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000008139 complexing agent Substances 0.000 description 1
- 125000000753 cycloalkyl group Chemical group 0.000 description 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 description 1
- 238000001739 density measurement Methods 0.000 description 1
- VXSASNNBOYCZMY-UHFFFAOYSA-M ethenyl-dimethyl-(2-phenylethyl)azanium;chloride Chemical compound [Cl-].C=C[N+](C)(C)CCC1=CC=CC=C1 VXSASNNBOYCZMY-UHFFFAOYSA-M 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 150000002734 metacrylic acid derivatives Chemical class 0.000 description 1
- FQPSGWSUVKBHSU-UHFFFAOYSA-N methacrylamide Chemical class CC(=C)C(N)=O FQPSGWSUVKBHSU-UHFFFAOYSA-N 0.000 description 1
- NXPPAOGUKPJVDI-UHFFFAOYSA-N naphthalene-1,2-diol Chemical compound C1=CC=CC2=C(O)C(O)=CC=C21 NXPPAOGUKPJVDI-UHFFFAOYSA-N 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 238000005375 photometry Methods 0.000 description 1
- XNGIFLGASWRNHJ-UHFFFAOYSA-L phthalate(2-) Chemical compound [O-]C(=O)C1=CC=CC=C1C([O-])=O XNGIFLGASWRNHJ-UHFFFAOYSA-L 0.000 description 1
- 230000010399 physical interaction Effects 0.000 description 1
- 229920002401 polyacrylamide Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920000139 polyethylene terephthalate Polymers 0.000 description 1
- 239000005020 polyethylene terephthalate Substances 0.000 description 1
- AFDCXHSYKIVOOQ-UHFFFAOYSA-K potassium;disodium;phosphate Chemical compound [Na+].[Na+].[K+].[O-]P([O-])([O-])=O AFDCXHSYKIVOOQ-UHFFFAOYSA-K 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 150000003440 styrenes Chemical class 0.000 description 1
- 125000000547 substituted alkyl group Chemical group 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 239000002344 surface layer Substances 0.000 description 1
- 229920003002 synthetic resin Polymers 0.000 description 1
- 239000000057 synthetic resin Substances 0.000 description 1
- 229920001897 terpolymer Polymers 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- 239000010936 titanium Substances 0.000 description 1
- 239000004408 titanium dioxide Substances 0.000 description 1
- USFMMZYROHDWPJ-UHFFFAOYSA-N trimethyl-[2-(2-methylprop-2-enoyloxy)ethyl]azanium Chemical compound CC(=C)C(=O)OCC[N+](C)(C)C USFMMZYROHDWPJ-UHFFFAOYSA-N 0.000 description 1
- VUEZMURBIBNRIB-UHFFFAOYSA-O trimethyl-[3-methyl-3-(prop-2-enoylamino)butyl]azanium Chemical compound C[N+](C)(C)CCC(C)(C)NC(=O)C=C VUEZMURBIBNRIB-UHFFFAOYSA-O 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
- G01N33/525—Multi-layer analytical elements
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US82298777A | 1977-08-08 | 1977-08-08 | |
US822,987 | 1977-08-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA1122889A true CA1122889A (en) | 1982-05-04 |
Family
ID=25237486
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA308,805A Expired CA1122889A (en) | 1977-08-08 | 1978-08-04 | Reduction of detectable species migration in elements for the analysis of liquids |
Country Status (5)
Country | Link |
---|---|
JP (1) | JPS5429700A (enrdf_load_stackoverflow) |
CA (1) | CA1122889A (enrdf_load_stackoverflow) |
DE (1) | DE2834713C2 (enrdf_load_stackoverflow) |
FR (1) | FR2400202A1 (enrdf_load_stackoverflow) |
GB (1) | GB2002514B (enrdf_load_stackoverflow) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5647761A (en) * | 1979-09-27 | 1981-04-30 | Fuji Photo Film Co Ltd | Laminated analyzing piece and immunity analyzing method using the same |
US4303408A (en) * | 1980-02-05 | 1981-12-01 | Eastman Kodak Company | Removal of interferents in analytical assays in a two phase interferent-removal zone |
JPS57142562A (en) * | 1981-02-27 | 1982-09-03 | Fuji Photo Film Co Ltd | Quantitative analysis film and colorimetric quantitative analysis |
JPS57208997A (en) * | 1981-06-17 | 1982-12-22 | Fuji Photo Film Co Ltd | Liquid analyzing material for oxidase enzyme reaction system |
US4390343A (en) * | 1981-07-06 | 1983-06-28 | Miles Laboratories, Inc. | Multilayer analytical element having an impermeable radiation diffusing and blocking layer |
JPS5818167A (ja) * | 1981-07-24 | 1983-02-02 | Fuji Photo Film Co Ltd | 分析フイルム及びこれを用いる分析方法 |
US4459358A (en) * | 1982-12-29 | 1984-07-10 | Polaroid Corporation | Multilayer element for analysis |
JPS6014141A (ja) * | 1983-07-06 | 1985-01-24 | Kyoto Daiichi Kagaku:Kk | 多層一体化分析用具 |
JPS62138198A (ja) * | 1985-12-10 | 1987-06-20 | Fuji Photo Film Co Ltd | 自己顕色性基質を含む乾式液体分析要素 |
US5063081A (en) * | 1988-11-14 | 1991-11-05 | I-Stat Corporation | Method of manufacturing a plurality of uniform microfabricated sensing devices having an immobilized ligand receptor |
EP0432642B1 (en) * | 1989-12-15 | 1998-06-17 | F. Hoffmann-La Roche Ag | Reagent composition, methods and kits for quantification of magnesium or calcium and magnesium |
US7288414B2 (en) * | 2005-04-19 | 2007-10-30 | Specialty Assays, Inc. | Use of phosphonazo III for the measurement of calcium, magnesium and sodium in analytical samples |
JP6191217B2 (ja) * | 2013-04-24 | 2017-09-06 | 凸版印刷株式会社 | 酸素インジケーター |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2280081A1 (fr) * | 1974-07-23 | 1976-02-20 | Kodak Pathe | Produit composite unitaire pour l'analyse chimique ou biologique |
CA1095819A (en) * | 1977-01-14 | 1981-02-17 | Eastman Kodak Company | Element for analysis of liquids |
-
1978
- 1978-08-04 CA CA308,805A patent/CA1122889A/en not_active Expired
- 1978-08-08 JP JP9588778A patent/JPS5429700A/ja active Granted
- 1978-08-08 FR FR7823308A patent/FR2400202A1/fr active Granted
- 1978-08-08 DE DE19782834713 patent/DE2834713C2/de not_active Expired
- 1978-08-08 GB GB7832636A patent/GB2002514B/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
JPS5429700A (en) | 1979-03-05 |
FR2400202B1 (enrdf_load_stackoverflow) | 1980-08-29 |
JPS6129460B2 (enrdf_load_stackoverflow) | 1986-07-07 |
GB2002514B (en) | 1982-01-20 |
DE2834713A1 (de) | 1979-02-22 |
FR2400202A1 (fr) | 1979-03-09 |
GB2002514A (en) | 1979-02-21 |
DE2834713C2 (de) | 1985-09-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US4166093A (en) | Reduction of detectable species migration in elements for the analysis of liquids | |
CA1122889A (en) | Reduction of detectable species migration in elements for the analysis of liquids | |
EP0769558B1 (en) | Blood glucose strip having reduced sensitivity to hematocrit | |
US4826759A (en) | Field assay for ligands | |
AU701834B2 (en) | Volume-independent diagnostic test carrier and methods in which it is used to determine an analyte | |
US4057394A (en) | Test device and method for determining blood hemoglobin | |
CA1094432A (en) | Colorimetric assay for bilirubin | |
JP2514878B2 (ja) | 固相アッセイ装置及びその使用法 | |
EP0088636B1 (en) | Quantitative analysis apparatus and method | |
FI56905C (fi) | Foerfarande och anordning foer automatisk maetning av agglutinationsprov t ex i spektrofotometer adsoptionsfotometer fluorometer eller nefelometer | |
MXPA97005534A (en) | Diagnostic test carrier with multiple layer test field and method in which it is used to determine an analyst or substance going to anali | |
EP0019786B1 (en) | Chemiluminescent analytical device and its use | |
US6602719B1 (en) | Method and device for detecting analytes in fluids | |
JPH076984B2 (ja) | 複数項目分析方法 | |
US4788153A (en) | Method for the determination of bilirubin and an element useful therein | |
US4412005A (en) | Determination of total bilirubin | |
EP0169055A2 (en) | Polymeric single layer analytical element | |
EP0041175B2 (en) | Ion specific analytical element | |
IE58565B1 (en) | Multilayer ion test means | |
EP0902287A1 (en) | Formulation for reducing urea effect for immunochromatography assays using urine samples | |
ATE173829T1 (de) | Turbidimetrisches immunassay mit messung der geschwindigkeit der trübungsveränderung nach dem anfang der immunpräzipitationsreaktion | |
KR100458978B1 (ko) | 헤마토크릿에대한감도가낮은혈액글루코즈스트립 | |
RU2056628C1 (ru) | Чувствительный элемент для определения ионов тяжелых металлов | |
EP0022673B1 (en) | Method for selective determination of conjugated or unconjugated bilirubin | |
JPH09509480A (ja) | 光学導波管を使用する超高感度の競合イムノアッセイ |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MKEX | Expiry |