CA1108633A - 1-aryloxy-2-hydroxy-3-aminopropanes and process for preparing same - Google Patents

1-aryloxy-2-hydroxy-3-aminopropanes and process for preparing same

Info

Publication number
CA1108633A
CA1108633A CA278,974A CA278974A CA1108633A CA 1108633 A CA1108633 A CA 1108633A CA 278974 A CA278974 A CA 278974A CA 1108633 A CA1108633 A CA 1108633A
Authority
CA
Canada
Prior art keywords
phenyl
propoxy
hydroxy
radical
crotonic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA278,974A
Other languages
English (en)
French (fr)
Inventor
Werner Fritsch
Ulrich Stache
Ernst Lindner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of CA1108633A publication Critical patent/CA1108633A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Pyridine Compounds (AREA)
CA278,974A 1976-05-25 1977-05-24 1-aryloxy-2-hydroxy-3-aminopropanes and process for preparing same Expired CA1108633A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP2623314.7 1976-05-25
DE2623314A DE2623314C2 (de) 1976-05-25 1976-05-25 1-Aryloxy-2-Hydroxy-3-aminopropane, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
CA1108633A true CA1108633A (en) 1981-09-08

Family

ID=5978907

Family Applications (1)

Application Number Title Priority Date Filing Date
CA278,974A Expired CA1108633A (en) 1976-05-25 1977-05-24 1-aryloxy-2-hydroxy-3-aminopropanes and process for preparing same

Country Status (18)

Country Link
JP (1) JPS5312827A (enrdf_load_stackoverflow)
AT (1) AT354421B (enrdf_load_stackoverflow)
AU (1) AU511704B2 (enrdf_load_stackoverflow)
BE (1) BE855041A (enrdf_load_stackoverflow)
CA (1) CA1108633A (enrdf_load_stackoverflow)
CH (5) CH637105A5 (enrdf_load_stackoverflow)
DE (1) DE2623314C2 (enrdf_load_stackoverflow)
DK (1) DK227177A (enrdf_load_stackoverflow)
ES (1) ES458957A1 (enrdf_load_stackoverflow)
FI (1) FI67698C (enrdf_load_stackoverflow)
FR (1) FR2353520A1 (enrdf_load_stackoverflow)
GB (1) GB1577670A (enrdf_load_stackoverflow)
HU (1) HU179198B (enrdf_load_stackoverflow)
IL (1) IL52148A (enrdf_load_stackoverflow)
IT (1) IT1077193B (enrdf_load_stackoverflow)
NL (1) NL7705587A (enrdf_load_stackoverflow)
SE (1) SE440903B (enrdf_load_stackoverflow)
ZA (1) ZA773120B (enrdf_load_stackoverflow)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2415622A1 (fr) * 1978-01-25 1979-08-24 Lipha Amino alcools derives de l'ortho-hydroxy cinnamate de methyle applicables notamment comme medicaments
DE2824764A1 (de) * 1978-06-06 1979-12-20 Hoechst Ag Neue pyridylpiperazinderivate und verfahren zu ihrer herstellung
EP0008711B1 (en) * 1978-08-15 1981-11-04 Smithkline Beckman Corporation A method of preparing a 2-hydroxy-3-isopropyl or a 2-hydroxy-3-tert-butylaminopropyl aromatic ether
FR2459235A1 (fr) * 1979-06-14 1981-01-09 Sanofi Sa Nouveaux derives de sulfonyl-aniline, leur procede de preparation et leur application therapeutique
JPH0629833B2 (ja) * 1984-06-15 1994-04-20 株式会社島津製作所 疲労試験機
GB8603120D0 (en) * 1986-02-07 1986-03-12 Pfizer Ltd Anti-dysrhythmia agents
DK1188747T3 (da) 1999-05-24 2006-01-23 Mitsubishi Pharma Corp Phenoxypropylaminforbindelser
DE19941657A1 (de) * 1999-09-01 2001-03-08 Schwabe Willmar Gmbh & Co Zimtsäurenitrile, Verfahren zu ihrer Herstellung und Verwendung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA945172A (en) * 1969-02-21 1974-04-09 Imperial Chemical Industries Limited Alkanolamine derivatives
FR2132570B1 (enrdf_load_stackoverflow) * 1971-04-09 1974-08-02 Lipha
BE791650R (fr) * 1971-11-18 1973-05-21 Ici Ltd Derives d'alkanolamines.
ES411826A1 (es) * 1973-02-20 1976-01-01 Liade Sa Lab Procedimiento de obtencion de 1-ariloxi - 2 - propanolami- nas farmacologicamente activos.

Also Published As

Publication number Publication date
DK227177A (da) 1977-11-26
JPS6214545B2 (enrdf_load_stackoverflow) 1987-04-02
AT354421B (de) 1979-01-10
ES458957A1 (es) 1978-07-16
SE7706059L (sv) 1977-11-26
IL52148A0 (en) 1977-07-31
FR2353520A1 (fr) 1977-12-30
BE855041A (fr) 1977-11-25
CH640507A5 (en) 1984-01-13
GB1577670A (en) 1980-10-29
NL7705587A (nl) 1977-11-29
JPS5312827A (en) 1978-02-04
AU511704B2 (en) 1980-09-04
SE440903B (sv) 1985-08-26
FI67698B (fi) 1985-01-31
CH637105A5 (en) 1983-07-15
AU2543477A (en) 1978-11-30
IL52148A (en) 1982-07-30
HU179198B (en) 1982-09-28
CH637109A5 (en) 1983-07-15
FI771630A7 (enrdf_load_stackoverflow) 1977-11-26
DE2623314C2 (de) 1984-08-02
ZA773120B (en) 1978-04-26
IT1077193B (it) 1985-05-04
CH637108A5 (en) 1983-07-15
DE2623314A1 (de) 1977-12-08
FI67698C (fi) 1985-05-10
FR2353520B1 (enrdf_load_stackoverflow) 1980-07-25
CH637107A5 (en) 1983-07-15
ATA370177A (de) 1979-06-15

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Legal Events

Date Code Title Description
MKEX Expiry