CA1083592A - Anticariogenic maloaluminate complexes - Google Patents
Anticariogenic maloaluminate complexesInfo
- Publication number
- CA1083592A CA1083592A CA283,451A CA283451A CA1083592A CA 1083592 A CA1083592 A CA 1083592A CA 283451 A CA283451 A CA 283451A CA 1083592 A CA1083592 A CA 1083592A
- Authority
- CA
- Canada
- Prior art keywords
- aluminum
- fluoride
- maloaluminate
- complexes
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000000170 anti-cariogenic effect Effects 0.000 title abstract description 15
- 239000000203 mixture Substances 0.000 claims abstract description 56
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- 229910052708 sodium Inorganic materials 0.000 claims description 3
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- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims 1
- 150000001768 cations Chemical class 0.000 claims 1
- 229910052700 potassium Inorganic materials 0.000 claims 1
- 239000011591 potassium Substances 0.000 claims 1
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- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 12
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- GFQYVLUOOAAOGM-UHFFFAOYSA-N zirconium(iv) silicate Chemical compound [Zr+4].[O-][Si]([O-])([O-])[O-] GFQYVLUOOAAOGM-UHFFFAOYSA-N 0.000 description 5
- 239000005995 Aluminium silicate Substances 0.000 description 4
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- BJEPYKJPYRNKOW-UHFFFAOYSA-L malate(2-) Chemical compound [O-]C(=O)C(O)CC([O-])=O BJEPYKJPYRNKOW-UHFFFAOYSA-L 0.000 description 3
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- IRPGOXJVTQTAAN-UHFFFAOYSA-N 2,2,3,3,3-pentafluoropropanal Chemical compound FC(F)(F)C(F)(F)C=O IRPGOXJVTQTAAN-UHFFFAOYSA-N 0.000 description 2
- KLZUFWVZNOTSEM-UHFFFAOYSA-K Aluminum fluoride Inorganic materials F[Al](F)F KLZUFWVZNOTSEM-UHFFFAOYSA-K 0.000 description 2
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- BSFVYMTXZLCFKX-UHFFFAOYSA-N hexadecan-1-ol;sulfuric acid Chemical compound OS(O)(=O)=O.CCCCCCCCCCCCCCCCO BSFVYMTXZLCFKX-UHFFFAOYSA-N 0.000 description 1
- 235000001050 hortel pimenta Nutrition 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 238000005342 ion exchange Methods 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 229940045996 isethionic acid Drugs 0.000 description 1
- 235000010494 karaya gum Nutrition 0.000 description 1
- NEMFQSKAPLGFIP-UHFFFAOYSA-N magnesiosodium Chemical compound [Na].[Mg] NEMFQSKAPLGFIP-UHFFFAOYSA-N 0.000 description 1
- HCWCAKKEBCNQJP-UHFFFAOYSA-N magnesium orthosilicate Chemical compound [Mg+2].[Mg+2].[O-][Si]([O-])([O-])[O-] HCWCAKKEBCNQJP-UHFFFAOYSA-N 0.000 description 1
- 238000003760 magnetic stirring Methods 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 150000004701 malic acid derivatives Chemical class 0.000 description 1
- 210000004373 mandible Anatomy 0.000 description 1
- 230000013011 mating Effects 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- OSWPMRLSEDHDFF-UHFFFAOYSA-N methyl salicylate Chemical compound COC(=O)C1=CC=CC=C1O OSWPMRLSEDHDFF-UHFFFAOYSA-N 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 229910052750 molybdenum Inorganic materials 0.000 description 1
- 239000001788 mono and diglycerides of fatty acids Substances 0.000 description 1
- 235000019960 monoglycerides of fatty acid Nutrition 0.000 description 1
- 229920001206 natural gum Polymers 0.000 description 1
- 210000003739 neck Anatomy 0.000 description 1
- 239000012299 nitrogen atmosphere Substances 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 238000010979 pH adjustment Methods 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 239000001415 potassium malate Substances 0.000 description 1
- SVICABYXKQIXBM-UHFFFAOYSA-L potassium malate Chemical compound [K+].[K+].[O-]C(=O)C(O)CC([O-])=O SVICABYXKQIXBM-UHFFFAOYSA-L 0.000 description 1
- 235000011033 potassium malate Nutrition 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- OGHBATFHNDZKSO-UHFFFAOYSA-N propan-2-olate Chemical compound CC(C)[O-] OGHBATFHNDZKSO-UHFFFAOYSA-N 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000002390 rotary evaporation Methods 0.000 description 1
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 1
- 229940081974 saccharin Drugs 0.000 description 1
- 235000019204 saccharin Nutrition 0.000 description 1
- 239000000901 saccharin and its Na,K and Ca salt Substances 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- GJPYYNMJTJNYTO-UHFFFAOYSA-J sodium aluminium sulfate Chemical compound [Na+].[Al+3].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O GJPYYNMJTJNYTO-UHFFFAOYSA-J 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- AQMNWCRSESPIJM-UHFFFAOYSA-M sodium metaphosphate Chemical compound [Na+].[O-]P(=O)=O AQMNWCRSESPIJM-UHFFFAOYSA-M 0.000 description 1
- 238000004611 spectroscopical analysis Methods 0.000 description 1
- 239000011550 stock solution Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 229910052712 strontium Inorganic materials 0.000 description 1
- 150000005846 sugar alcohols Polymers 0.000 description 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- ZZIZZTHXZRDOFM-XFULWGLBSA-N tamsulosin hydrochloride Chemical compound [H+].[Cl-].CCOC1=CC=CC=C1OCCN[C@H](C)CC1=CC=C(OC)C(S(N)(=O)=O)=C1 ZZIZZTHXZRDOFM-XFULWGLBSA-N 0.000 description 1
- 229960003080 taurine Drugs 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 210000004357 third molar Anatomy 0.000 description 1
- 229910001432 tin ion Inorganic materials 0.000 description 1
- IUTCEZPPWBHGIX-UHFFFAOYSA-N tin(2+) Chemical compound [Sn+2] IUTCEZPPWBHGIX-UHFFFAOYSA-N 0.000 description 1
- 229940100613 topical solution Drugs 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 150000003628 tricarboxylic acids Chemical class 0.000 description 1
- VXYADVIJALMOEQ-UHFFFAOYSA-K tris(lactato)aluminium Chemical compound CC(O)C(=O)O[Al](OC(=O)C(C)O)OC(=O)C(C)O VXYADVIJALMOEQ-UHFFFAOYSA-K 0.000 description 1
- 229910052720 vanadium Inorganic materials 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/06—Aluminium compounds
- C07F5/069—Aluminium compounds without C-aluminium linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Cosmetics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71044376A | 1976-08-02 | 1976-08-02 | |
| US710,443 | 1976-08-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1083592A true CA1083592A (en) | 1980-08-12 |
Family
ID=24854052
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA283,451A Expired CA1083592A (en) | 1976-08-02 | 1977-07-25 | Anticariogenic maloaluminate complexes |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4042680A (OSRAM) |
| JP (1) | JPS5341416A (OSRAM) |
| AU (1) | AU512765B2 (OSRAM) |
| CA (1) | CA1083592A (OSRAM) |
| DE (1) | DE2734648A1 (OSRAM) |
| FR (1) | FR2360597A1 (OSRAM) |
| GB (1) | GB1589886A (OSRAM) |
| IT (1) | IT1079906B (OSRAM) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1081804B (it) * | 1977-06-07 | 1985-05-21 | Scharper Spa | Procedimento di preparazione di tris (idrossimetil)-aminometan-lattato-diidrossialluminato |
| US4267164A (en) * | 1980-01-31 | 1981-05-12 | Block Drug Company Inc. | Effervescent stannous fluoride tablet |
| GB2100126B (en) | 1981-06-11 | 1984-08-01 | Colgate Palmolive Co | A dentifrice |
| US4401648A (en) * | 1982-03-29 | 1983-08-30 | Colgate-Palmolive Company | Dental cream composition |
| US4414199A (en) * | 1982-07-15 | 1983-11-08 | Amway Corporation | Toothpaste |
| JPH0742219B2 (ja) * | 1984-07-26 | 1995-05-10 | ライオン株式会社 | 口腔用組成物 |
| US4976954A (en) * | 1986-12-02 | 1990-12-11 | Purdue Research Foundation | Anticariogenic compositions |
| US5064640A (en) * | 1986-12-02 | 1991-11-12 | Purdue Research Foundation | Anticariogenic compositions |
| NO172275C (no) * | 1987-05-01 | 1993-06-30 | Purdue Research Foundation | Oralt antitannstenpreparat |
| JP2558188B2 (ja) * | 1991-06-10 | 1996-11-27 | 花王株式会社 | 入浴剤組成物 |
| US5188819A (en) * | 1992-02-21 | 1993-02-23 | Purdue Research Foundation | Manufacture of aluminum-based anticariogenic compositions |
| US20080274065A1 (en) * | 2006-05-09 | 2008-11-06 | Richard Scott Robinson | Oral Care Regimen |
| BRPI0711271A2 (pt) | 2006-05-09 | 2011-11-08 | Colgate Palmolive Co | método de limpeza de uma superfìcie oral, de manutenção da saúde oral e/ou de aumento da saúde oral |
| MX2010005004A (es) * | 2008-02-08 | 2010-05-27 | Colgate Palmolive Co | Composiciones y dispositivos. |
| MX2010005190A (es) * | 2008-02-08 | 2010-06-03 | Colgate Palmolive Co | Hilo dental. |
| TWI389876B (zh) | 2008-02-08 | 2013-03-21 | Colgate Palmolive Co | 鹽的製造方法 |
| AR070592A1 (es) | 2008-02-08 | 2010-04-21 | Colgate Palmolive Co | Composiciones para el blanqueamiento dental |
| CN102037360B (zh) | 2008-02-08 | 2016-10-05 | 高露洁-棕榄公司 | 口腔护理方法和系统 |
| JP2011510095A (ja) * | 2008-02-08 | 2011-03-31 | コルゲート・パーモリブ・カンパニー | 歯用シーラント［０００１］この出願は２００８年２月８日に出願された米国一連番号６１／０２７，４２５の利益を主張し、その内容を本明細書に援用する。 |
| US20090202452A1 (en) * | 2008-02-08 | 2009-08-13 | Colgate-Palmolive Company | Oral care regimen |
| BRPI0907102A2 (pt) * | 2008-02-08 | 2016-05-03 | Colgate Palmolive Co | composição dental, e, método para eliminar ou reduzir o desconforto e a dor associados com a hipersensibilidade da dentina |
| BRPI0907106A2 (pt) * | 2008-02-08 | 2016-05-03 | Colgate Palmolive Co | bebida, e, método para melhorar a saúde oral. |
| AU2008349847C1 (en) * | 2008-02-08 | 2012-12-13 | Colgate-Palmolive Company | Oral care product and methods of use and manufacture thereof |
| EP2247278A4 (en) * | 2008-02-08 | 2014-02-19 | Colgate Palmolive Co | COMPOSITIONS AND METHODS OF CLEANING |
| TWI374756B (en) * | 2008-02-08 | 2012-10-21 | Colgate Palmolive Co | Compositions and methods comprising basic amino acid peptides and proteases |
| CA2705299C (en) * | 2008-02-08 | 2016-12-06 | Richard Scott Robinson | Dental wipe |
| EP3943064A1 (en) * | 2008-02-08 | 2022-01-26 | Colgate-Palmolive Company | Oral care product and methods of use and manufacture thereof |
| CN102215811A (zh) * | 2008-02-08 | 2011-10-12 | 高露洁-棕榄公司 | 泡腾组合物 |
| MX2010005002A (es) * | 2008-02-08 | 2010-05-24 | Colgate Palmolive Co | Cepillo de dientes para el cuidado oral. |
| BRPI0822121A2 (pt) | 2008-02-08 | 2014-09-30 | Colgate Palmolive Co | Composição para cuidado oral, e uso da mesma |
| BRPI0906462A2 (pt) * | 2008-02-08 | 2015-07-14 | Colgate Palmolive Co | Método para tratar, melhorar, inibir ou evitar boca seca, saliva artificial, uso de um aminoácido básico em forma livre ou de sal, e, aminoácido básico em forma livre ou de sal |
| EP2513048B1 (en) | 2009-12-18 | 2016-11-16 | Colgate-Palmolive Company | Methods for production of high concentration of arginine bicarbonate solution at high pressure |
| EP2513047B1 (en) | 2009-12-18 | 2015-04-01 | Colgate-Palmolive Company | Methods for production of arginine bicarbonate at low pressure |
| AU2010356102B2 (en) | 2010-06-23 | 2013-09-05 | Colgate-Palmolive Company | Therapeutic oral composition |
| US11033594B2 (en) | 2012-12-06 | 2021-06-15 | Colgate-Palmolive Company | Oral gel for sensitivity and tooth pain |
| WO2021062607A1 (en) | 2019-09-30 | 2021-04-08 | The Procter & Gamble Company | Oral care compositions comprising hops beta acid and amino acid |
| CN114449996B (zh) | 2019-09-30 | 2024-10-01 | 宝洁公司 | 包含啤酒花β酸和金属离子的口腔护理组合物 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3485858A (en) * | 1968-04-03 | 1969-12-23 | Mobil Oil Corp | Metal alkyl,or alkoxy metal alkyl,ester tetrapropenylsuccinates |
| US3584025A (en) * | 1968-08-30 | 1971-06-08 | Allied Chem | Hydrocarbon gels |
-
1975
- 1975-08-02 US US05/710,443 patent/US4042680A/en not_active Expired - Lifetime
-
1977
- 1977-07-25 CA CA283,451A patent/CA1083592A/en not_active Expired
- 1977-07-29 GB GB31936/77A patent/GB1589886A/en not_active Expired
- 1977-08-01 DE DE19772734648 patent/DE2734648A1/de active Granted
- 1977-08-01 IT IT50519/77A patent/IT1079906B/it active
- 1977-08-02 AU AU27544/77A patent/AU512765B2/en not_active Expired
- 1977-08-02 JP JP9291277A patent/JPS5341416A/ja active Granted
- 1977-08-02 FR FR7723810A patent/FR2360597A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| GB1589886A (en) | 1981-05-20 |
| FR2360597B1 (OSRAM) | 1981-02-06 |
| AU2754477A (en) | 1979-02-08 |
| DE2734648C2 (OSRAM) | 1988-11-17 |
| FR2360597A1 (fr) | 1978-03-03 |
| US4042680A (en) | 1977-08-16 |
| AU512765B2 (en) | 1980-10-23 |
| JPS6156217B2 (OSRAM) | 1986-12-01 |
| DE2734648A1 (de) | 1978-02-09 |
| IT1079906B (it) | 1985-05-13 |
| JPS5341416A (en) | 1978-04-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |