CA1082727A - 4-(d-3-amino-3-carboxypropoxy) phenylglyoxylic acid oxime derivatives, nocardicin side chain - Google Patents

4-(d-3-amino-3-carboxypropoxy) phenylglyoxylic acid oxime derivatives, nocardicin side chain

Info

Publication number
CA1082727A
CA1082727A CA288,251A CA288251A CA1082727A CA 1082727 A CA1082727 A CA 1082727A CA 288251 A CA288251 A CA 288251A CA 1082727 A CA1082727 A CA 1082727A
Authority
CA
Canada
Prior art keywords
amino
formula
ester
oxime
protected
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA288,251A
Other languages
English (en)
French (fr)
Inventor
Gary A. Koppel
Robin D.G. Cooper
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of CA1082727A publication Critical patent/CA1082727A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1896—Compounds having one or more Si-O-acyl linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA288,251A 1976-11-05 1977-10-06 4-(d-3-amino-3-carboxypropoxy) phenylglyoxylic acid oxime derivatives, nocardicin side chain Expired CA1082727A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US73916076A 1976-11-05 1976-11-05
US739,160 1976-11-05
US825,344 1977-08-17
US05/825,344 US4355172A (en) 1976-11-05 1977-08-17 Process for 4-(D-3-amino-3-carboxypropoxy)-phenylglyoxylic acid oxime derivatives

Publications (1)

Publication Number Publication Date
CA1082727A true CA1082727A (en) 1980-07-29

Family

ID=27113483

Family Applications (1)

Application Number Title Priority Date Filing Date
CA288,251A Expired CA1082727A (en) 1976-11-05 1977-10-06 4-(d-3-amino-3-carboxypropoxy) phenylglyoxylic acid oxime derivatives, nocardicin side chain

Country Status (10)

Country Link
US (1) US4355172A (enExample)
JP (1) JPS5359644A (enExample)
CA (1) CA1082727A (enExample)
DE (1) DE2747573A1 (enExample)
ES (1) ES463889A1 (enExample)
FR (1) FR2370038A1 (enExample)
GB (1) GB1587278A (enExample)
IE (1) IE45593B1 (enExample)
IL (1) IL52988A (enExample)
NL (1) NL7712164A (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006267387B2 (en) * 2005-07-11 2010-11-18 Mitsubishi Tanabe Pharma Corporation An oxime derivative and preparations thereof
JP2008019241A (ja) * 2007-03-01 2008-01-31 Mitsubishi Tanabe Pharma Corp オキシム誘導体及びその製法
FR2966150B1 (fr) * 2010-10-15 2012-10-12 Adisseo France Sas Procede de preparation de la 2-hydroxybutyrolactone
CN105732386B (zh) * 2016-04-11 2018-07-06 安徽金泉生物科技股份有限公司 一种药物中间体酯类化合物的合成方法
CN105777538B (zh) * 2016-04-11 2018-07-10 安徽金泉生物科技股份有限公司 一种医药中间体苄基酯类化合物的合成方法
CN116396316B (zh) * 2023-03-29 2025-04-18 无锡科华生物科技有限公司 一种3-甲基苯并[d]恶唑-2(3H)-酮-5-硼酸频哪醇酯的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3875207A (en) * 1967-01-25 1975-04-01 Ciba Geigy Corp Process for the temporary protection of amino groups in peptide syntheses
US3852290A (en) * 1971-09-17 1974-12-03 Nitto Boseki Co Ltd Thiocarbonates
US3891692A (en) * 1972-05-03 1975-06-24 Merck & Co Inc N-(cyclopropylalkoxycarbonyl)amino acids
US3923977A (en) * 1972-08-29 1975-12-02 Fujisawa Pharmaceutical Co Antibiotic FR-1923 substance
CH618161A5 (en) * 1974-07-04 1980-07-15 Fujisawa Pharmaceutical Co Process for the preparation of azetidinone derivatives
JPS606354B2 (ja) * 1976-03-30 1985-02-18 藤沢薬品工業株式会社 ジ置換アルコキシベンゼン誘導体およびその塩類

Also Published As

Publication number Publication date
IL52988A0 (en) 1977-11-30
IE45593L (en) 1978-05-05
NL7712164A (nl) 1978-05-09
DE2747573A1 (de) 1978-05-18
US4355172A (en) 1982-10-19
JPS5359644A (en) 1978-05-29
ES463889A1 (es) 1978-12-16
IE45593B1 (en) 1982-10-06
IL52988A (en) 1981-07-31
GB1587278A (en) 1981-04-01
FR2370038B1 (enExample) 1980-05-16
FR2370038A1 (fr) 1978-06-02

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Legal Events

Date Code Title Description
MKEX Expiry