CA1081230A - (2-pyrimidinyl-thio) alkanoic acid amides and their preparation - Google Patents

(2-pyrimidinyl-thio) alkanoic acid amides and their preparation

Info

Publication number
CA1081230A
CA1081230A CA273,420A CA273420A CA1081230A CA 1081230 A CA1081230 A CA 1081230A CA 273420 A CA273420 A CA 273420A CA 1081230 A CA1081230 A CA 1081230A
Authority
CA
Canada
Prior art keywords
pyrimidinyl
xylidino
thio
formula
chloro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA273,420A
Other languages
English (en)
French (fr)
Inventor
Carlo Scolastico
Giovanni Tronooni
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lpb Istituto Farmaceutico SpA
Original Assignee
Lpb Istituto Farmaceutico SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lpb Istituto Farmaceutico SpA filed Critical Lpb Istituto Farmaceutico SpA
Application granted granted Critical
Publication of CA1081230A publication Critical patent/CA1081230A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/38One sulfur atom
CA273,420A 1976-03-17 1977-03-08 (2-pyrimidinyl-thio) alkanoic acid amides and their preparation Expired CA1081230A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21317/76A IT1063074B (it) 1976-03-17 1976-03-17 Ammidi di acidi(z-pirimidiniltio)al canoici quali agent antilipemici

Publications (1)

Publication Number Publication Date
CA1081230A true CA1081230A (en) 1980-07-08

Family

ID=11180012

Family Applications (1)

Application Number Title Priority Date Filing Date
CA273,420A Expired CA1081230A (en) 1976-03-17 1977-03-08 (2-pyrimidinyl-thio) alkanoic acid amides and their preparation

Country Status (14)

Country Link
JP (1) JPS52113983A (es)
BE (1) BE852401A (es)
CA (1) CA1081230A (es)
CH (1) CH631169A5 (es)
DE (1) DE2711149C3 (es)
DK (1) DK143558C (es)
ES (1) ES456902A1 (es)
FR (1) FR2344545A1 (es)
GB (1) GB1532195A (es)
IT (1) IT1063074B (es)
MX (1) MX4818E (es)
NL (1) NL166933C (es)
PH (1) PH14865A (es)
SE (1) SE434743B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5810525Y2 (ja) * 1978-08-04 1983-02-25 三菱電機株式会社 小型電気掃除機
IT1211096B (it) * 1981-08-20 1989-09-29 Lpb Ist Farm Pirimidine e s.triazinici adattivita' ipolipidemizzante.
JPS59199673A (ja) * 1983-04-25 1984-11-12 Sumitomo Chem Co Ltd 含窒素複素環化合物、その製造法およびそれを有効成分とする有害生物防除剤
FR2636064B1 (fr) * 1988-09-08 1990-12-07 Fabre Sa Pierre Thioformamidines, leur preparation et leur application en tant que medicaments
EP1399426A2 (en) * 2001-06-12 2004-03-24 Active Pass Pharmaceuticals, Inc. Compounds, compositions and methods for modulating beta-amyloid production

Also Published As

Publication number Publication date
FR2344545B1 (es) 1980-03-21
GB1532195A (en) 1978-11-15
DE2711149C3 (de) 1980-12-11
DK143558C (da) 1982-03-22
MX4818E (es) 1982-10-20
IT1063074B (it) 1985-02-11
NL7702821A (nl) 1977-09-20
JPS52113983A (en) 1977-09-24
SE434743B (sv) 1984-08-13
DK143558B (da) 1981-09-07
BE852401A (fr) 1977-07-01
ES456902A1 (es) 1978-01-16
DK114377A (da) 1977-09-18
DE2711149A1 (de) 1977-09-29
SE7702922L (sv) 1977-09-18
FR2344545A1 (fr) 1977-10-14
PH14865A (en) 1982-01-08
CH631169A5 (en) 1982-07-30
DE2711149B2 (es) 1980-04-24
NL166933C (nl) 1981-10-15
JPS554746B2 (es) 1980-01-31
NL166933B (nl) 1981-05-15

Similar Documents

Publication Publication Date Title
US3702849A (en) 4-(isoquinolin-1-yl) piperazine-1-carboxylic acid esters
CA1147338A (en) 4-amino-3-quinolinecarboxylic acids and esters-antisecretory, anti-ulcer compounds
CA1060029A (en) N-(1-benzylpyrrolldinyl 2-alkyl) substituted benzamides and derivatives thereof
EP0387821B1 (de) 2-Alkyl-4-arylmethylaminochinoline, ihre Verwendung und daraus hergestellte Arzneimittel
FR2656609A1 (fr) Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique.
US4123530A (en) N-cyclohexyl-piperazino acetamides and propionamides
CA1081230A (en) (2-pyrimidinyl-thio) alkanoic acid amides and their preparation
US3823152A (en) 3-substituted-2-piperidinethiones and homologues thereof
US3474107A (en) N-aromatic substituted acid amides
US4691018A (en) Pyridine derivatives and their use as anti-allergic agents
US4210660A (en) Benzamide derivatives
US4001228A (en) 2-thiol-4,5-diphenyloxazole s-derivatives
CA1314881C (en) Anti-anxiety agents
US5084456A (en) Oxazolopyridine compounds
EP0447116B1 (en) Urea derivatives, their production, and pharmaceutical compositions containing them
EP0326106A2 (en) Alkylene diamines
US3985875A (en) ω-(N-acylamino)alkylphosphoryl ethanolamines, pharmaceutical compositions containing them, and their uses
US4188484A (en) (2-Pyrimidinyl-thio)-alkanoic acid amides and their preparation
CA1110628A (en) N-phenethylacetamide compounds and process for preparation thereof
US4216221A (en) 1,3-Disubstituted (2-thio)ureas
US4705787A (en) Quinazolinone derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same
US4268511A (en) 3-Amino(1H,3H)quinazoline-2,4-dione derivatives and their therapeutic applications
DD232045A5 (de) Verfahren zur herstellung von vorwirkstoffen entzuendungshemmender oxicame
US5091403A (en) Sulfinyl imidazole derivatives and antiulcer agents containing the same
US4742068A (en) Dihydropyridine compounds having 1,4,4-trisubstitution useful as antihypertensive agents

Legal Events

Date Code Title Description
MKEX Expiry