GB1532195A - (2-pyrimidinyl-thio)-alkanoic acid amides and their preparation - Google Patents
(2-pyrimidinyl-thio)-alkanoic acid amides and their preparationInfo
- Publication number
- GB1532195A GB1532195A GB10995/77A GB1099577A GB1532195A GB 1532195 A GB1532195 A GB 1532195A GB 10995/77 A GB10995/77 A GB 10995/77A GB 1099577 A GB1099577 A GB 1099577A GB 1532195 A GB1532195 A GB 1532195A
- Authority
- GB
- United Kingdom
- Prior art keywords
- preparation
- pyrimidinyl
- thio
- acid amides
- alkanoic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/38—One sulfur atom
Abstract
Novel amides of (2-pyrimidylthio)-alkanoic acids possessing an antilipemic activity and methods for their preparation by reaction of an activated derivative of the corresponding acids, such as an acyl chloride or mixed anhydride, and a secondary amine, or by reaction of the corresponding (2-pyrimidinylthio)-alkanoic acids and aziridine or finally by fusion of the amides of (4,6-dichloro-2-pyrimidinylthio)-alkanoic acids with a secondary amine are described.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT21317/76A IT1063074B (en) | 1976-03-17 | 1976-03-17 | ACID AMIDES (Z-PYRIMIDINYLTI) AL CANOICS AS ANTI-LIPEMIC AGENTS |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1532195A true GB1532195A (en) | 1978-11-15 |
Family
ID=11180012
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB10995/77A Expired GB1532195A (en) | 1976-03-17 | 1977-03-15 | (2-pyrimidinyl-thio)-alkanoic acid amides and their preparation |
Country Status (14)
Country | Link |
---|---|
JP (1) | JPS52113983A (en) |
BE (1) | BE852401A (en) |
CA (1) | CA1081230A (en) |
CH (1) | CH631169A5 (en) |
DE (1) | DE2711149C3 (en) |
DK (1) | DK143558C (en) |
ES (1) | ES456902A1 (en) |
FR (1) | FR2344545A1 (en) |
GB (1) | GB1532195A (en) |
IT (1) | IT1063074B (en) |
MX (1) | MX4818E (en) |
NL (1) | NL166933C (en) |
PH (1) | PH14865A (en) |
SE (1) | SE434743B (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5810525Y2 (en) * | 1978-08-04 | 1983-02-25 | 三菱電機株式会社 | small vacuum cleaner |
IT1211096B (en) * | 1981-08-20 | 1989-09-29 | Lpb Ist Farm | PYRIMIDINES AND S.TRIAZINICS HYPOLIPIDEMIZING ADAPTITY. |
JPS59199673A (en) * | 1983-04-25 | 1984-11-12 | Sumitomo Chem Co Ltd | Nitrogen-containing heterocyclic compound, its preparation and pesticide containing the same |
FR2636064B1 (en) * | 1988-09-08 | 1990-12-07 | Fabre Sa Pierre | THIOFORMAMIDINES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS |
EP1399426A2 (en) * | 2001-06-12 | 2004-03-24 | Active Pass Pharmaceuticals, Inc. | Compounds, compositions and methods for modulating beta-amyloid production |
-
1976
- 1976-03-17 IT IT21317/76A patent/IT1063074B/en active
-
1977
- 1977-02-23 PH PH19485A patent/PH14865A/en unknown
- 1977-03-08 CA CA273,420A patent/CA1081230A/en not_active Expired
- 1977-03-14 CH CH317377A patent/CH631169A5/en not_active IP Right Cessation
- 1977-03-14 BE BE2055735A patent/BE852401A/en not_active IP Right Cessation
- 1977-03-15 GB GB10995/77A patent/GB1532195A/en not_active Expired
- 1977-03-15 FR FR7707617A patent/FR2344545A1/en active Granted
- 1977-03-15 SE SE7702922A patent/SE434743B/en unknown
- 1977-03-15 DE DE2711149A patent/DE2711149C3/en not_active Expired
- 1977-03-16 JP JP2811277A patent/JPS52113983A/en active Granted
- 1977-03-16 DK DK114377A patent/DK143558C/en not_active IP Right Cessation
- 1977-03-16 MX MX775544U patent/MX4818E/en unknown
- 1977-03-16 ES ES456902A patent/ES456902A1/en not_active Expired
- 1977-03-16 NL NL7702821.A patent/NL166933C/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
FR2344545B1 (en) | 1980-03-21 |
DE2711149C3 (en) | 1980-12-11 |
DK143558C (en) | 1982-03-22 |
MX4818E (en) | 1982-10-20 |
IT1063074B (en) | 1985-02-11 |
NL7702821A (en) | 1977-09-20 |
JPS52113983A (en) | 1977-09-24 |
CA1081230A (en) | 1980-07-08 |
SE434743B (en) | 1984-08-13 |
DK143558B (en) | 1981-09-07 |
BE852401A (en) | 1977-07-01 |
ES456902A1 (en) | 1978-01-16 |
DK114377A (en) | 1977-09-18 |
DE2711149A1 (en) | 1977-09-29 |
SE7702922L (en) | 1977-09-18 |
FR2344545A1 (en) | 1977-10-14 |
PH14865A (en) | 1982-01-08 |
CH631169A5 (en) | 1982-07-30 |
DE2711149B2 (en) | 1980-04-24 |
NL166933C (en) | 1981-10-15 |
JPS554746B2 (en) | 1980-01-31 |
NL166933B (en) | 1981-05-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PCNP | Patent ceased through non-payment of renewal fee |