CA1080720A - Aminopropoxy-indole derivatives - Google Patents

Aminopropoxy-indole derivatives

Info

Publication number
CA1080720A
CA1080720A CA259,050A CA259050A CA1080720A CA 1080720 A CA1080720 A CA 1080720A CA 259050 A CA259050 A CA 259050A CA 1080720 A CA1080720 A CA 1080720A
Authority
CA
Canada
Prior art keywords
formula
compound
methyl
addition salt
acid addition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA259,050A
Other languages
English (en)
French (fr)
Inventor
Franz Troxler
Fritz Seemann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Priority to CA333,572A priority Critical patent/CA1080721A/en
Application granted granted Critical
Publication of CA1080720A publication Critical patent/CA1080720A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA259,050A 1975-08-15 1976-08-13 Aminopropoxy-indole derivatives Expired CA1080720A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA333,572A CA1080721A (en) 1975-08-15 1979-08-10 Aminopropoxy-indole derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1071475 1975-08-15

Publications (1)

Publication Number Publication Date
CA1080720A true CA1080720A (en) 1980-07-01

Family

ID=4366041

Family Applications (1)

Application Number Title Priority Date Filing Date
CA259,050A Expired CA1080720A (en) 1975-08-15 1976-08-13 Aminopropoxy-indole derivatives

Country Status (28)

Country Link
US (1) US4434176A (OSRAM)
JP (2) JPS5223073A (OSRAM)
AT (1) AT363070B (OSRAM)
AU (1) AU505719B2 (OSRAM)
BE (1) BE845197R (OSRAM)
CA (1) CA1080720A (OSRAM)
CY (1) CY1225A (OSRAM)
DE (1) DE2635209C2 (OSRAM)
DK (1) DK152120C (OSRAM)
ES (1) ES450681A1 (OSRAM)
FI (1) FI63751C (OSRAM)
FR (1) FR2320743A2 (OSRAM)
GB (2) GB1575509A (OSRAM)
HK (1) HK35884A (OSRAM)
IE (1) IE43797B1 (OSRAM)
IL (2) IL50263A (OSRAM)
KE (1) KE3404A (OSRAM)
MY (1) MY8500135A (OSRAM)
NL (2) NL176362C (OSRAM)
NO (1) NO762735L (OSRAM)
NZ (1) NZ181764A (OSRAM)
PH (1) PH13356A (OSRAM)
PT (1) PT65477B (OSRAM)
SE (1) SE414633B (OSRAM)
SG (1) SG84883G (OSRAM)
SU (1) SU649313A3 (OSRAM)
YU (1) YU198876A (OSRAM)
ZA (1) ZA764883B (OSRAM)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2830211A1 (de) * 1977-07-21 1979-02-01 Sandoz Ag Substituierte indol-derivate, ihre herstellung und verwendung
JPS58106499A (ja) * 1981-12-19 1983-06-24 株式会社東芝 燃料交換装置のクランプ解除機構
NL8600137A (nl) * 1985-02-05 1986-09-01 Sandoz Ag Farmaceutische preparaten die desgewenst met een diureticum gecombineerde 3-aminopropoxyindolen bevatten, alsmede werkwijzen voor het toepassen van deze preparaten.
US5174210A (en) * 1990-04-27 1992-12-29 Heidelberger Druckmaschinen Aktiengesellschaft Preparation of the inking unit of a printing press for a change of printing job
EP0750608A1 (en) * 1994-01-28 1997-01-02 Cal International Limited Pharmaceutical product comprising a salicylate of an esterifiable beta-blocker
BRPI0410840A (pt) * 2003-05-30 2006-07-04 Ranbaxy Lab Ltd derivados substituìdos de pirrol, composição farmacêutica contendo os mesmos e processo para sua preparação
JP2009514851A (ja) * 2005-11-08 2009-04-09 ランバクシー ラボラトリーズ リミテッド （３ｒ，５ｒ）−７−［２−（４−フルオロフェニル）−５−イソプロピル−３−フェニル−４−［（４−ヒドロキシメチルフェニルアミノ）カルボニル］−ピロール−１−イル］−３，５−ジヒドロキシ−ヘプタン酸ヘミカルシウム塩の製法
AR059838A1 (es) * 2006-03-14 2008-04-30 Ranbaxy Lab Ltd Formulaciones para dosis estabilizantes de estatina
MX2009000439A (es) * 2006-07-14 2009-02-04 Ranbaxy Lab Ltd Formas polimorficas de un inhibidor de hmg-coa reductasa y usos de las mismas.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH532040A (de) * 1970-03-24 1972-12-31 Sandoz Ag Verfahren zur Herstellung neuer Indolderivate
US3751429A (en) * 1970-03-24 1973-08-07 Sandoz Ltd 4-(3-amino-2-substituted propoxy)indole derivatives
SE375771B (OSRAM) * 1970-09-30 1975-04-28 Sandoz Ag
CH545784A (en) * 1971-01-07 1974-02-15 Beta blocking and anti-arrhythmic indole derivs - prepd by catalytic de-benzylation of 4-(3-benzyl aminopropoxy) indoles
CH545783A (en) * 1971-01-07 1974-02-15 Novel indole derivs - prepn by reacting 4-(2-hydroxy-3-isopropylaminopropoxy) indoles and acid anhy-drides

Also Published As

Publication number Publication date
IL50263A0 (en) 1976-10-31
HK35884A (en) 1984-05-04
MY8500135A (en) 1985-12-31
IE43797L (en) 1977-02-15
DE2635209A1 (de) 1977-02-24
BE845197R (fr) 1977-02-14
FR2320743A2 (fr) 1977-03-11
SU649313A3 (ru) 1979-02-25
NL930134I2 (nl) 1996-11-01
GB1575510A (en) 1980-09-24
NL930134I1 (nl) 1993-11-01
PT65477A (fr) 1976-09-01
FI63751C (fi) 1983-08-10
ZA764883B (en) 1978-03-29
IL58163A0 (en) 1979-12-30
SE7608865L (sv) 1977-02-16
JPS5223073A (en) 1977-02-21
FI63751B (fi) 1983-04-29
NL7608902A (nl) 1977-02-17
IE43797B1 (en) 1981-06-03
SE414633B (sv) 1980-08-11
JPS568834B2 (OSRAM) 1981-02-25
PT65477B (fr) 1978-05-10
YU198876A (en) 1982-05-31
NO762735L (OSRAM) 1977-02-16
AT363070B (de) 1981-07-10
DE2635209C2 (de) 1983-01-27
DK152120C (da) 1988-06-20
ATA602576A (de) 1980-12-15
JPS5649318A (en) 1981-05-02
DK357576A (da) 1977-02-16
NZ181764A (en) 1978-06-20
SG84883G (en) 1985-01-11
IL50263A (en) 1980-06-30
GB1575509A (en) 1980-09-24
KE3404A (en) 1985-02-01
US4434176A (en) 1984-02-28
NL176362B (nl) 1984-11-01
FR2320743B2 (OSRAM) 1978-11-17
FI762258A7 (OSRAM) 1977-02-16
CY1225A (en) 1984-04-06
ES450681A1 (es) 1977-11-16
NL176362C (nl) 1985-04-01
PH13356A (en) 1980-03-20
DK152120B (da) 1988-02-01
AU505719B2 (en) 1979-11-29
AU1684176A (en) 1978-02-16

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Legal Events

Date Code Title Description
MKEX Expiry