SE414633B - Forfarande for framstellning av nya 4-(3-tert butylamino-propoxi)-2-metyl-indolderivat med terapeutisk verkan - Google Patents

Forfarande for framstellning av nya 4-(3-tert butylamino-propoxi)-2-metyl-indolderivat med terapeutisk verkan

Info

Publication number
SE414633B
SE414633B SE7608865A SE7608865A SE414633B SE 414633 B SE414633 B SE 414633B SE 7608865 A SE7608865 A SE 7608865A SE 7608865 A SE7608865 A SE 7608865A SE 414633 B SE414633 B SE 414633B
Authority
SE
Sweden
Prior art keywords
indold
propoxy
derivatives
methyl
procedure
Prior art date
Application number
SE7608865A
Other languages
English (en)
Swedish (sv)
Other versions
SE7608865L (sv
Inventor
F Troxler
F Seemann
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of SE7608865L publication Critical patent/SE7608865L/xx
Publication of SE414633B publication Critical patent/SE414633B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SE7608865A 1975-08-15 1976-08-06 Forfarande for framstellning av nya 4-(3-tert butylamino-propoxi)-2-metyl-indolderivat med terapeutisk verkan SE414633B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1071475 1975-08-15

Publications (2)

Publication Number Publication Date
SE7608865L SE7608865L (sv) 1977-02-16
SE414633B true SE414633B (sv) 1980-08-11

Family

ID=4366041

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7608865A SE414633B (sv) 1975-08-15 1976-08-06 Forfarande for framstellning av nya 4-(3-tert butylamino-propoxi)-2-metyl-indolderivat med terapeutisk verkan

Country Status (28)

Country Link
US (1) US4434176A (xx)
JP (2) JPS5223073A (xx)
AT (1) AT363070B (xx)
AU (1) AU505719B2 (xx)
BE (1) BE845197R (xx)
CA (1) CA1080720A (xx)
CY (1) CY1225A (xx)
DE (1) DE2635209C2 (xx)
DK (1) DK152120C (xx)
ES (1) ES450681A1 (xx)
FI (1) FI63751C (xx)
FR (1) FR2320743A2 (xx)
GB (2) GB1575509A (xx)
HK (1) HK35884A (xx)
IE (1) IE43797B1 (xx)
IL (2) IL50263A (xx)
KE (1) KE3404A (xx)
MY (1) MY8500135A (xx)
NL (2) NL176362C (xx)
NO (1) NO762735L (xx)
NZ (1) NZ181764A (xx)
PH (1) PH13356A (xx)
PT (1) PT65477B (xx)
SE (1) SE414633B (xx)
SG (1) SG84883G (xx)
SU (1) SU649313A3 (xx)
YU (1) YU198876A (xx)
ZA (1) ZA764883B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2830211A1 (de) * 1977-07-21 1979-02-01 Sandoz Ag Substituierte indol-derivate, ihre herstellung und verwendung
JPS58106499A (ja) * 1981-12-19 1983-06-24 株式会社東芝 燃料交換装置のクランプ解除機構
HU196125B (en) * 1985-02-05 1988-10-28 Sandoz Ag Process for producing pharmaceutical comprising 3-(aminopropoxy)-indole derivatives combined with diuretic
US5174210A (en) * 1990-04-27 1992-12-29 Heidelberger Druckmaschinen Aktiengesellschaft Preparation of the inking unit of a printing press for a change of printing job
EP0750608A1 (en) * 1994-01-28 1997-01-02 Cal International Limited Pharmaceutical product comprising a salicylate of an esterifiable beta-blocker
CN1812983A (zh) * 2003-05-30 2006-08-02 兰贝克赛实验室有限公司 取代的吡咯衍生物及其作为hmg-co抑制剂的用途
EP1948599A1 (en) * 2005-11-08 2008-07-30 Ranbaxy Laboratories Limited Process for (3r, 5r)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt
CL2007000667A1 (es) * 2006-03-14 2008-03-14 Ranbaxi Lab Ltd Composicion farmaceutica que comprende al acido 7-[2-(4-fluorofenil)-5-isopropil-3-fenil-4-[(4-hidroximetilfenilamino)carbonil]pirrol-1-il]-3,5-dihidroxi-heptanoico o una sal y al menos un agente estabilizante; procedimiento de preparacion, util en e
AU2007274724B2 (en) * 2006-07-14 2012-07-26 Ranbaxy Laboratories Limited Polymorphic forms of an HMG-CoA reductase inhibitor and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3751429A (en) * 1970-03-24 1973-08-07 Sandoz Ltd 4-(3-amino-2-substituted propoxy)indole derivatives
CH532040A (de) * 1970-03-24 1972-12-31 Sandoz Ag Verfahren zur Herstellung neuer Indolderivate
SE375771B (xx) * 1970-09-30 1975-04-28 Sandoz Ag
CH545783A (en) * 1971-01-07 1974-02-15 Novel indole derivs - prepn by reacting 4-(2-hydroxy-3-isopropylaminopropoxy) indoles and acid anhy-drides
CH545784A (en) * 1971-01-07 1974-02-15 Beta blocking and anti-arrhythmic indole derivs - prepd by catalytic de-benzylation of 4-(3-benzyl aminopropoxy) indoles

Also Published As

Publication number Publication date
YU198876A (en) 1982-05-31
JPS5223073A (en) 1977-02-21
NL930134I1 (nl) 1993-11-01
IL50263A0 (en) 1976-10-31
IE43797L (en) 1977-02-15
AT363070B (de) 1981-07-10
NL176362C (nl) 1985-04-01
NL176362B (nl) 1984-11-01
ATA602576A (de) 1980-12-15
IE43797B1 (en) 1981-06-03
FR2320743A2 (fr) 1977-03-11
PT65477A (fr) 1976-09-01
DE2635209C2 (de) 1983-01-27
ES450681A1 (es) 1977-11-16
HK35884A (en) 1984-05-04
DE2635209A1 (de) 1977-02-24
AU505719B2 (en) 1979-11-29
JPS568834B2 (xx) 1981-02-25
NZ181764A (en) 1978-06-20
PH13356A (en) 1980-03-20
GB1575510A (en) 1980-09-24
SE7608865L (sv) 1977-02-16
US4434176A (en) 1984-02-28
GB1575509A (en) 1980-09-24
ZA764883B (en) 1978-03-29
FI63751B (fi) 1983-04-29
FR2320743B2 (xx) 1978-11-17
KE3404A (en) 1985-02-01
IL58163A0 (en) 1979-12-30
MY8500135A (en) 1985-12-31
CY1225A (en) 1984-04-06
NO762735L (xx) 1977-02-16
FI762258A (xx) 1977-02-16
FI63751C (fi) 1983-08-10
BE845197R (fr) 1977-02-14
DK152120B (da) 1988-02-01
SU649313A3 (ru) 1979-02-25
IL50263A (en) 1980-06-30
NL930134I2 (nl) 1996-11-01
NL7608902A (nl) 1977-02-17
AU1684176A (en) 1978-02-16
CA1080720A (en) 1980-07-01
PT65477B (fr) 1978-05-10
DK357576A (da) 1977-02-16
SG84883G (en) 1985-01-11
DK152120C (da) 1988-06-20
JPS5649318A (en) 1981-05-02

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