CA1076560A - 3-heterocyclic thiomethylcephalosporins - Google Patents
3-heterocyclic thiomethylcephalosporinsInfo
- Publication number
- CA1076560A CA1076560A CA163,909A CA163909A CA1076560A CA 1076560 A CA1076560 A CA 1076560A CA 163909 A CA163909 A CA 163909A CA 1076560 A CA1076560 A CA 1076560A
- Authority
- CA
- Canada
- Prior art keywords
- amino
- alpha
- cephem
- triazol
- hydroxyphenylacetamido
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US262903A US3867380A (en) | 1971-02-18 | 1972-06-14 | 3-Heterocyclic thiomethylcephalosporins |
| US00289499A US3855213A (en) | 1971-02-18 | 1972-09-15 | 3-heterocyclic thiomethyl-cephalosporins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1076560A true CA1076560A (en) | 1980-04-29 |
Family
ID=26949532
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA163,909A Expired CA1076560A (en) | 1972-06-14 | 1973-02-16 | 3-heterocyclic thiomethylcephalosporins |
| CA167,072A Expired CA999293A (en) | 1972-06-14 | 1973-03-26 | .alpha.-AMINO-P-HYDROXYPHENYLACETAMIDOCEPHALOSPORINS |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA167,072A Expired CA999293A (en) | 1972-06-14 | 1973-03-26 | .alpha.-AMINO-P-HYDROXYPHENYLACETAMIDOCEPHALOSPORINS |
Country Status (20)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR780000197B1 (en) * | 1972-12-26 | 1978-05-26 | Bristol Myers Co | Method for preparing antibacterial agent |
| GB1439419A (en) * | 1973-01-31 | 1976-06-16 | Bristol Myers Co | 3-thiolated-7-acylamido-cephalosporanic acid derivatives |
| GB1476981A (en) * | 1974-06-05 | 1977-06-16 | Bristol Myers Co | Substituted penicillanic acids |
| CA1074784A (en) * | 1974-09-06 | 1980-04-01 | Sumitomo Chemical Company | N-ACYLAMINO-.alpha.-ARYLACETAMIDO CEPHALOSPORINS |
| JPS5346995A (en) * | 1976-10-12 | 1978-04-27 | Sangyo Kagaku Kenkyu Kyokai | Antibacterial agents |
| NL162387C (nl) * | 1977-09-06 | 1980-05-16 | Gist Brocades Nv | Werkwijze voor het bereiden van 6-(d-alpha-amino-p- -hydroxyfenylacetamido)penicillanzuur. |
| JPS6010226U (ja) * | 1983-06-30 | 1985-01-24 | 松下電工株式会社 | 昇降装置 |
| JPS6182606A (ja) * | 1984-09-29 | 1986-04-26 | 東芝ライテック株式会社 | 昇降装置 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA698494B (en) * | 1969-02-26 | 1971-07-28 | Lilly Co Eli | Sulfur-containing cephalosporing antibiotics |
| US3641021A (en) * | 1969-04-18 | 1972-02-08 | Lilly Co Eli | 3 7-(ring-substituted) cephalosporin compounds |
-
1973
- 1973-02-16 CA CA163,909A patent/CA1076560A/en not_active Expired
- 1973-02-19 AU AU52345/73A patent/AU464107B2/en not_active Expired
- 1973-02-21 GB GB851173A patent/GB1363833A/en not_active Expired
- 1973-02-23 SE SE7302579A patent/SE416472B/sv unknown
- 1973-02-28 NL NL7302817A patent/NL7302817A/xx unknown
- 1973-03-01 ES ES412207A patent/ES412207A1/es not_active Expired
- 1973-03-14 IE IE423/73A patent/IE37409B1/xx unknown
- 1973-03-14 FR FR7309052A patent/FR2187298B1/fr not_active Expired
- 1973-03-24 JP JP3401573A patent/JPS5518716B2/ja not_active Expired
- 1973-03-26 CA CA167,072A patent/CA999293A/en not_active Expired
- 1973-03-30 GB GB1530873A patent/GB1358027A/en not_active Expired
- 1973-03-30 SE SE7304545A patent/SE404190B/xx unknown
- 1973-04-04 IE IE533/73A patent/IE37499B1/xx unknown
- 1973-04-04 DE DE2316867A patent/DE2316867C2/de not_active Expired
- 1973-04-09 CH CH508373A patent/CH586709A5/xx not_active IP Right Cessation
- 1973-04-09 CH CH508273A patent/CH589093A5/xx not_active IP Right Cessation
- 1973-04-09 ES ES413501A patent/ES413501A1/es not_active Expired
- 1973-04-13 NL NL7305206A patent/NL7305206A/xx unknown
- 1973-04-27 IL IL42126A patent/IL42126A/xx unknown
- 1973-05-03 DK DK242173AA patent/DK142913B/da not_active IP Right Cessation
- 1973-05-10 FR FR7316936A patent/FR2187299B1/fr not_active Expired
- 1973-05-17 FI FI1610/73A patent/FI56843C/fi active
- 1973-05-17 JP JP48055142A patent/JPS5953274B2/ja not_active Expired
- 1973-05-25 PH PH14656*A patent/PH9941A/en unknown
- 1973-06-08 DD DD171434A patent/DD105238A5/xx unknown
- 1973-06-08 AT AT510473A patent/AT324560B/de not_active IP Right Cessation
- 1973-06-13 PL PL1973163317A patent/PL91074B1/pl unknown
- 1973-06-14 HU HUSI1323A patent/HU168689B/hu unknown
- 1973-06-14 AR AR248585A patent/AR197237A1/es active
Also Published As
Similar Documents
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| US3880848A (en) | 7-Trifluorome thylsulfinylacetamido cephalosporins | |
| US3985739A (en) | 3-Heterocyclic thiomethylcephalosporins | |
| US3917588A (en) | {60 -Aminoacyl cephalosporin ethers | |
| US4162314A (en) | 7[2(Substituted phenyl)2-(amino)acetamido]cephalosporin derivatives | |
| WO1988003924A1 (en) | Novel cephalosporin derivatives and their crystalline derivatives | |
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| US4138556A (en) | 7-Amino-3-(sulfoalkyl substituted oxadiazolylthiomethyl) cephalosporins | |
| EP0329785A1 (en) | Cephalosporin derivatives | |
| US4018921A (en) | Substituted phenylglycylcephalosporins | |
| US3850916A (en) | 7-amino-3-(s-(1,2,3-triazole-5-yl)-thiomethyl)-3-cephem-4-carboxylic acid and salts thereof | |
| JPS6259283A (ja) | セフアロスポリン化合物 | |
| US3953439A (en) | Substituted phenylglycylcephalosporins | |
| EP0186586B1 (en) | Cephem compounds and the production thereof | |
| US4137314A (en) | 7-Dithioacetamido cephalosporins and pharmaceutical compositions and methods employing them having antibacterial activity | |
| JPS6322570A (ja) | １−メタンスルホニルオキシ−６−トリフルオロメチル−１ｈ−ベンゾトリアゾ−ル及びセファロスポリン誘導体の製造方法 | |
| CA1097612A (en) | Alpha-aminoacyl cephalosporin ethers | |
| GB1584861A (en) | Cephalosporin compounds |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |