CA1069505A - Process for preparing 1-polyhaloalkyl-3, 4-dihydro-2-(1h)-quinazolinones - Google Patents
Process for preparing 1-polyhaloalkyl-3, 4-dihydro-2-(1h)-quinazolinonesInfo
- Publication number
- CA1069505A CA1069505A CA270,156A CA270156A CA1069505A CA 1069505 A CA1069505 A CA 1069505A CA 270156 A CA270156 A CA 270156A CA 1069505 A CA1069505 A CA 1069505A
- Authority
- CA
- Canada
- Prior art keywords
- formula
- dihydro
- compound
- defined above
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
- C07D239/80—Oxygen atoms
- C07D239/82—Oxygen atoms with an aryl radical attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP692076A JPS5291885A (en) | 1976-01-23 | 1976-01-23 | 3,4-dihydro-2(1h)-quinazolinone derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1069505A true CA1069505A (en) | 1980-01-08 |
Family
ID=11651662
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA270,156A Expired CA1069505A (en) | 1976-01-23 | 1977-01-20 | Process for preparing 1-polyhaloalkyl-3, 4-dihydro-2-(1h)-quinazolinones |
Country Status (13)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5271483A (en) * | 1975-12-11 | 1977-06-14 | Sumitomo Chem Co Ltd | Synthesis of 2(1h)-quinazolinone derivatives |
| US4282226A (en) * | 1978-04-26 | 1981-08-04 | E. R. Squibb & Sons, Inc. | Thioxopyrazolo[1,5-c]quinazoline derivatives, anti-allergic compositions and methods for treating allergic conditions by parenteral administration, aerosol or insufflation |
| EP1394242A3 (en) * | 2002-08-07 | 2004-04-21 | Rohm And Haas Company | Cyclic thioureas and their use as additives for lubricating oils |
| CN1738623A (zh) * | 2003-01-23 | 2006-02-22 | 夏尔控股公司 | 治疗血小板增多症的制剂和方法 |
| US7700608B2 (en) * | 2004-08-04 | 2010-04-20 | Shire Holdings Ag | Quinazoline derivatives and their use in the treatment of thrombocythemia |
| US20060030574A1 (en) * | 2004-08-04 | 2006-02-09 | Shire Holdings Ag | Quinazoline derivatives useful for the treatment of peripheral arterial disease and as phosphodiesterase inhibitors |
| US7910597B2 (en) * | 2006-11-28 | 2011-03-22 | Shire Llc | Substituted quinazolines |
| US8304420B2 (en) | 2006-11-28 | 2012-11-06 | Shire Llc | Substituted quinazolines for reducing platelet count |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3748331A (en) * | 1971-05-06 | 1973-07-24 | Sandoz Ag | 1,4-disubstituted-methylenedioxy -2-(1h)-quinazolinones and quinazolinthiones |
-
1976
- 1976-01-23 JP JP692076A patent/JPS5291885A/ja active Pending
- 1976-12-27 US US05/754,640 patent/US4048168A/en not_active Expired - Lifetime
- 1976-12-30 NL NL7614574A patent/NL7614574A/xx not_active Application Discontinuation
-
1977
- 1977-01-05 GB GB263/77A patent/GB1525892A/en not_active Expired
- 1977-01-17 AT AT22777A patent/AT353276B/de not_active IP Right Cessation
- 1977-01-17 FR FR7701170A patent/FR2338934A1/fr active Granted
- 1977-01-19 SE SE7700533A patent/SE422324B/xx unknown
- 1977-01-20 DK DK22277AA patent/DK141064B/da not_active IP Right Cessation
- 1977-01-20 CA CA270,156A patent/CA1069505A/en not_active Expired
- 1977-01-21 MX MX775376U patent/MX3959E/es unknown
- 1977-01-21 HU HU77SU937A patent/HU174389B/hu unknown
- 1977-01-21 DE DE19772702530 patent/DE2702530A1/de not_active Withdrawn
- 1977-01-21 CH CH78877A patent/CH625231A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DK141064B (da) | 1980-01-07 |
| HU174389B (hu) | 1979-12-28 |
| MX3959E (es) | 1981-10-15 |
| CH625231A5 (US06653308-20031125-C00199.png) | 1981-09-15 |
| DK141064C (US06653308-20031125-C00199.png) | 1980-06-23 |
| FR2338934B1 (US06653308-20031125-C00199.png) | 1980-12-19 |
| SE422324B (sv) | 1982-03-01 |
| US4048168A (en) | 1977-09-13 |
| DE2702530A1 (de) | 1977-07-28 |
| FR2338934A1 (fr) | 1977-08-19 |
| ATA22777A (de) | 1979-04-15 |
| GB1525892A (en) | 1978-09-20 |
| AT353276B (de) | 1979-11-12 |
| NL7614574A (nl) | 1977-07-26 |
| AU2131477A (en) | 1978-02-23 |
| JPS5291885A (en) | 1977-08-02 |
| SE7700533L (sv) | 1977-07-24 |
| DK22277A (US06653308-20031125-C00199.png) | 1977-07-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |