CA1069438A - Stable solutions and processes for their preparation - Google Patents

Stable solutions and processes for their preparation

Info

Publication number
CA1069438A
CA1069438A CA253,612A CA253612A CA1069438A CA 1069438 A CA1069438 A CA 1069438A CA 253612 A CA253612 A CA 253612A CA 1069438 A CA1069438 A CA 1069438A
Authority
CA
Canada
Prior art keywords
component
composition according
carbon atoms
weight
alcohol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA253,612A
Other languages
English (en)
French (fr)
Inventor
Lothar Ehrhardt
Volker Hartmann
Ludwig Patt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Application granted granted Critical
Publication of CA1069438A publication Critical patent/CA1069438A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA253,612A 1975-05-31 1976-05-28 Stable solutions and processes for their preparation Expired CA1069438A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2524184 1975-05-31

Publications (1)

Publication Number Publication Date
CA1069438A true CA1069438A (en) 1980-01-08

Family

ID=5947910

Family Applications (1)

Application Number Title Priority Date Filing Date
CA253,612A Expired CA1069438A (en) 1975-05-31 1976-05-28 Stable solutions and processes for their preparation

Country Status (26)

Country Link
JP (1) JPS585167B2 (de)
AT (1) AT355725B (de)
AU (1) AU508625B2 (de)
BE (1) BE842348A (de)
CA (1) CA1069438A (de)
CS (1) CS205023B2 (de)
DD (1) DD125597A5 (de)
DK (1) DK154606C (de)
ES (1) ES448372A1 (de)
FI (1) FI761461A (de)
FR (1) FR2313059A1 (de)
GB (1) GB1539083A (de)
GR (1) GR60264B (de)
HK (1) HK15383A (de)
HU (1) HU171514B (de)
IE (1) IE42999B1 (de)
IL (1) IL49668A (de)
MY (1) MY8300013A (de)
NL (1) NL172616C (de)
NO (1) NO145262C (de)
NZ (1) NZ180984A (de)
PT (1) PT65151B (de)
SE (1) SE426782B (de)
SU (2) SU677664A3 (de)
YU (1) YU133076A (de)
ZA (1) ZA763138B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2935515A1 (de) * 1979-09-03 1981-03-19 Fa. Dr. Willmar Schwabe, 7500 Karlsruhe Arzneipraeparat
FR2483235A1 (fr) * 1980-05-28 1981-12-04 Fabre Sa Pierre Compositions a usage topique contenant des alcaloides de l'ergot de seigle et de vinca rosea destinees au traitement des hyperseborrhees
DE3227122A1 (de) * 1982-07-20 1984-01-26 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim Stabile loesungen von mutterkornalkaloiden
HU192050B (en) * 1983-04-22 1987-05-28 Sandoz Ag Process for production of medical preparative containing co-dergocrin and one piridin-dicarbonic acid diesthertype calcium-antagonist
IT1200609B (it) * 1985-04-04 1989-01-27 Poli Ind Chimica Spa Composizione farmaceutice per il trattamento delle turbe cerebrovascolari e del cervello anziano
DE102007014947B4 (de) 2007-03-23 2010-05-27 Axxonis Pharma Ag Stabilisierte wässrige Lösungen von Ergolinverbindungen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD43402A (de) *
US2033921A (en) * 1931-08-28 1936-03-17 Squibb & Sons Inc Solution of ergot alkaloids
US1969382A (en) * 1932-05-21 1934-08-07 Squibb & Sons Inc Preparation of a stable hydro-alcoholic extract of ergot

Also Published As

Publication number Publication date
FR2313059A1 (fr) 1976-12-31
AT355725B (de) 1980-03-25
JPS585167B2 (ja) 1983-01-29
HK15383A (en) 1983-05-20
YU133076A (en) 1984-08-31
DK228676A (da) 1976-12-01
CS205023B2 (en) 1981-04-30
ZA763138B (en) 1978-01-25
SU952106A3 (ru) 1982-08-15
GR60264B (en) 1978-04-20
JPS51144720A (en) 1976-12-13
NL172616C (nl) 1983-10-03
IL49668A0 (en) 1976-09-30
HU171514B (hu) 1978-01-28
SU677664A3 (ru) 1979-07-30
NL172616B (nl) 1983-05-02
DK154606B (da) 1988-12-05
DD125597A5 (de) 1977-05-04
ATA390476A (de) 1979-08-15
IE42999L (en) 1976-11-30
DK154606C (da) 1989-05-01
PT65151B (fr) 1978-02-06
NO145262B (no) 1981-11-09
NO761760L (de) 1976-12-01
SE426782B (sv) 1983-02-14
GB1539083A (en) 1979-01-24
NO145262C (no) 1982-02-17
MY8300013A (en) 1983-12-31
PT65151A (fr) 1976-06-01
AU1442276A (en) 1977-12-01
FR2313059B1 (de) 1978-12-15
NZ180984A (en) 1978-06-20
SE7605841L (sv) 1976-12-01
ES448372A1 (es) 1978-03-01
FI761461A (de) 1976-12-01
IL49668A (en) 1979-10-31
IE42999B1 (en) 1980-12-03
BE842348A (fr) 1976-11-29
NL7605745A (nl) 1976-12-02
AU508625B2 (en) 1980-03-27

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Legal Events

Date Code Title Description
MKEX Expiry