CA1063112A - Substituted ureido-compounds - Google Patents

Substituted ureido-compounds

Info

Publication number
CA1063112A
CA1063112A CA240,512A CA240512A CA1063112A CA 1063112 A CA1063112 A CA 1063112A CA 240512 A CA240512 A CA 240512A CA 1063112 A CA1063112 A CA 1063112A
Authority
CA
Canada
Prior art keywords
general formula
grouping
phenyl
hydroxy
propyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA240,512A
Other languages
English (en)
French (fr)
Inventor
Bernard R. Neustadt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scherico Ltd
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scherico Ltd filed Critical Scherico Ltd
Application granted granted Critical
Publication of CA1063112A publication Critical patent/CA1063112A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/42Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/32Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
    • C07C275/34Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/95Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96Two oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/28Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA240,512A 1974-12-02 1975-11-26 Substituted ureido-compounds Expired CA1063112A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52860374A 1974-12-02 1974-12-02

Publications (1)

Publication Number Publication Date
CA1063112A true CA1063112A (en) 1979-09-25

Family

ID=24106378

Family Applications (1)

Application Number Title Priority Date Filing Date
CA240,512A Expired CA1063112A (en) 1974-12-02 1975-11-26 Substituted ureido-compounds

Country Status (26)

Country Link
JP (1) JPS5182239A (de)
AR (2) AR219478A1 (de)
AT (1) AT357557B (de)
AU (1) AU501512B2 (de)
BE (1) BE835899A (de)
CA (1) CA1063112A (de)
CH (1) CH623044A5 (de)
CS (1) CS188259B2 (de)
DD (1) DD124730A5 (de)
DE (1) DE2552933A1 (de)
DK (1) DK535275A (de)
FI (1) FI753332A (de)
FR (1) FR2346000A1 (de)
GB (1) GB1507340A (de)
HU (1) HU175541B (de)
IE (1) IE42759B1 (de)
IL (1) IL48557A (de)
IT (1) IT1051024B (de)
LU (1) LU73888A1 (de)
NL (1) NL7513804A (de)
NO (1) NO146497C (de)
PH (1) PH14474A (de)
PL (2) PL102327B1 (de)
SE (2) SE7513331L (de)
SU (2) SU655311A3 (de)
ZA (1) ZA757457B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52111541A (en) * 1976-02-19 1977-09-19 Scherico Ltd Substituted ureido compound and medical composition containing it as active ingredient
US4107303A (en) 1976-06-24 1978-08-15 E. I. Du Pont De Nemours And Company Antihypertensive hexafluorohydroxyisopropyl benzazepines and benzazocines
DE2839462A1 (de) * 1978-09-11 1980-03-27 Basf Ag Aroylharnstoffe
US6316503B1 (en) 1999-03-15 2001-11-13 Tularik Inc. LXR modulators
EP1476425A4 (de) 2002-01-30 2010-05-05 Amgen Inc Heterocyclische arylsulfonamidobenzyl verbindungen
CA2474433A1 (en) 2002-01-30 2003-08-07 Tularik Inc. Arylsulfonamidobenzylic compounds
US20030199578A1 (en) * 2002-04-19 2003-10-23 Turner Sean C. Naphthalene amides as potassium channel openers
RU2712163C2 (ru) * 2014-10-24 2020-01-24 Оно Фармасьютикал Ко., Лтд. Активатор kcnq2-5 каналов
JP6197971B1 (ja) * 2016-04-22 2017-09-20 小野薬品工業株式会社 Kcnq2〜5チャネル関連疾患の予防および/または治療剤

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3453284A (en) * 1966-01-19 1969-07-01 Du Pont Certain 2-(substituted-anilino)-2-oxazolines
DE1670751A1 (de) * 1966-09-27 1970-12-23 Bayer Ag Verfahren zur Herstellung von 2-Phenylamino-2-oxazolinen
FR1543534A (fr) * 1966-09-27 1968-10-25 Bayer Ag Procédé de fabrication de 2-phénylimino-oxazolidines
DE1670752A1 (de) * 1966-09-27 1970-12-23 Bayer Ag Verfahren zur Herstellung von 2-Phenylamino-oxazolinen
FR1543535A (fr) * 1966-09-27 1968-10-25 Bayer Ag Procédé de fabrication de 2-phénylamino-2-oxazolines

Also Published As

Publication number Publication date
SU655311A3 (ru) 1979-03-30
ZA757457B (en) 1976-11-24
DE2552933A1 (de) 1976-06-10
DK535275A (da) 1976-06-03
FR2346000A1 (fr) 1977-10-28
AR218436A1 (es) 1980-06-13
LU73888A1 (de) 1976-09-06
AU501512B2 (en) 1979-06-21
JPS5182239A (de) 1976-07-19
IE42759L (en) 1976-06-02
CH623044A5 (en) 1981-05-15
IL48557A0 (en) 1976-01-30
AR219478A1 (es) 1980-08-29
BE835899A (fr) 1976-05-25
FR2346000B1 (de) 1978-11-17
PH14474A (en) 1981-08-07
NO753984L (de) 1976-06-03
NO146497B (no) 1982-07-05
FI753332A (de) 1976-06-03
IE42759B1 (en) 1980-10-08
SE7513331L (sv) 1976-06-03
CS188259B2 (en) 1979-02-28
PL99122B1 (pl) 1978-06-30
SU685146A3 (ru) 1979-09-05
IT1051024B (it) 1981-04-21
AT357557B (de) 1980-07-25
AU8698975A (en) 1977-06-02
SE8004364L (sv) 1980-06-11
DD124730A5 (de) 1977-03-09
NO146497C (no) 1982-10-13
GB1507340A (en) 1978-04-12
IL48557A (en) 1979-05-31
ATA898575A (de) 1979-12-15
HU175541B (hu) 1980-08-28
PL102327B1 (pl) 1979-03-31
NL7513804A (nl) 1976-06-04

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