CA1052780A - 6'-n-methylkanamycin a and b derivatives - Google Patents

6'-n-methylkanamycin a and b derivatives

Info

Publication number
CA1052780A
CA1052780A CA239,778A CA239778A CA1052780A CA 1052780 A CA1052780 A CA 1052780A CA 239778 A CA239778 A CA 239778A CA 1052780 A CA1052780 A CA 1052780A
Authority
CA
Canada
Prior art keywords
amino
alpha
compound
formula
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA239,778A
Other languages
English (en)
French (fr)
Inventor
Takayuki Naito
Soichiro Toda
Susumu Nakagawa
Yukio Narita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of CA1052780A publication Critical patent/CA1052780A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA239,778A 1974-12-09 1975-11-17 6'-n-methylkanamycin a and b derivatives Expired CA1052780A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53078774A 1974-12-09 1974-12-09

Publications (1)

Publication Number Publication Date
CA1052780A true CA1052780A (en) 1979-04-17

Family

ID=24114972

Family Applications (1)

Application Number Title Priority Date Filing Date
CA239,778A Expired CA1052780A (en) 1974-12-09 1975-11-17 6'-n-methylkanamycin a and b derivatives

Country Status (17)

Country Link
JP (1) JPS51105036A (xx)
BE (1) BE836292A (xx)
CA (1) CA1052780A (xx)
CH (1) CH621558A5 (xx)
CS (1) CS191168B2 (xx)
DE (1) DE2555405A1 (xx)
DK (1) DK149775B (xx)
FR (1) FR2293941A1 (xx)
GB (1) GB1535215A (xx)
HU (1) HU175575B (xx)
IE (1) IE42179B1 (xx)
LU (1) LU73957A1 (xx)
NL (1) NL7514322A (xx)
SE (1) SE435513B (xx)
SU (1) SU581873A3 (xx)
YU (1) YU306475A (xx)
ZA (1) ZA757652B (xx)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9938217B2 (en) 2016-07-01 2018-04-10 Res Usa, Llc Fluidized bed membrane reactor
US9981896B2 (en) 2016-07-01 2018-05-29 Res Usa, Llc Conversion of methane to dimethyl ether
US10189763B2 (en) 2016-07-01 2019-01-29 Res Usa, Llc Reduction of greenhouse gas emission

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0000473B1 (en) * 1977-06-24 1981-03-11 Scherico Ltd. Process for preparing aminoglycoside derivatives, novel derivatives obtained and pharmaceutical compositions containing such derivatives
KR101296099B1 (ko) 2007-11-21 2014-02-26 아카오젠, 인코포레이티드 항균성 아미노글리코사이드 동족체
WO2010132759A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of dibekacin
WO2010132757A2 (en) * 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010132760A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of tobramycin
WO2010132765A2 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010132768A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of sisomicin
RU2604665C2 (ru) 2010-09-13 2016-12-10 Юниверсити Оф Цюрих Лечение бактериальных инфекционных заболеваний

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9938217B2 (en) 2016-07-01 2018-04-10 Res Usa, Llc Fluidized bed membrane reactor
US9981896B2 (en) 2016-07-01 2018-05-29 Res Usa, Llc Conversion of methane to dimethyl ether
US10189763B2 (en) 2016-07-01 2019-01-29 Res Usa, Llc Reduction of greenhouse gas emission

Also Published As

Publication number Publication date
GB1535215A (en) 1978-12-13
DK551075A (da) 1976-06-10
SE7513804L (sv) 1976-06-10
DE2555405A1 (de) 1976-06-10
HU175575B (hu) 1980-09-28
YU306475A (en) 1982-05-31
NL7514322A (nl) 1976-06-11
LU73957A1 (xx) 1976-11-11
CS191168B2 (en) 1979-06-29
CH621558A5 (en) 1981-02-13
SE435513B (sv) 1984-10-01
DK149775B (da) 1986-09-29
FR2293941B1 (xx) 1978-11-10
ZA757652B (en) 1976-11-24
BE836292A (fr) 1976-06-04
FR2293941A1 (fr) 1976-07-09
SU581873A3 (ru) 1977-11-25
JPS51105036A (en) 1976-09-17
IE42179B1 (en) 1980-06-18
AU8688275A (en) 1977-06-02
IE42179L (en) 1976-06-09

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