CA1048549A - Derives de la n-butylamine a usages pharmaceutiques et procede pour leur preparation - Google Patents

Derives de la n-butylamine a usages pharmaceutiques et procede pour leur preparation

Info

Publication number
CA1048549A
CA1048549A CA75227044A CA227044A CA1048549A CA 1048549 A CA1048549 A CA 1048549A CA 75227044 A CA75227044 A CA 75227044A CA 227044 A CA227044 A CA 227044A CA 1048549 A CA1048549 A CA 1048549A
Authority
CA
Canada
Prior art keywords
propyl
acid
butylamine
process according
ethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA75227044A
Other languages
English (en)
Inventor
Charles Pigerol
Pierre Eymard
Jean-Claude Vernieres
Jean-Pierre Werbenec
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Labaz SA
Original Assignee
Labaz SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labaz SA filed Critical Labaz SA
Priority to CA310,149A priority Critical patent/CA1056730A/fr
Application granted granted Critical
Publication of CA1048549A publication Critical patent/CA1048549A/fr
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/04—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups
    • C07C209/06—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of halogen atoms
    • C07C209/08—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of halogen atoms with formation of amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/62—Preparation of compounds containing amino groups bound to a carbon skeleton by cleaving carbon-to-nitrogen, sulfur-to-nitrogen, or phosphorus-to-nitrogen bonds, e.g. hydrolysis of amides, N-dealkylation of amines or quaternary ammonium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
    • C07C209/70—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton by reduction of unsaturated amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C211/03—Monoamines
    • C07C211/08—Monoamines containing alkyl groups having a different number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/126—Acids containing more than four carbon atoms
    • C07C53/128—Acids containing more than four carbon atoms the carboxylic group being bound to a carbon atom bound to at least two other carbon atoms, e.g. neo-acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA75227044A 1974-05-20 1975-05-15 Derives de la n-butylamine a usages pharmaceutiques et procede pour leur preparation Expired CA1048549A (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA310,149A CA1056730A (fr) 1974-05-20 1978-08-28 Preparations pharmaceutiques et veterinaires pour le traitement de la maladie de parkinson et des troubles extrapyramidaux causes par les neuroleptiques

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BE144519A BE815273A (fr) 1974-05-20 1974-05-20 Derives actifs de methylamine

Publications (1)

Publication Number Publication Date
CA1048549A true CA1048549A (fr) 1979-02-13

Family

ID=3842664

Family Applications (1)

Application Number Title Priority Date Filing Date
CA75227044A Expired CA1048549A (fr) 1974-05-20 1975-05-15 Derives de la n-butylamine a usages pharmaceutiques et procede pour leur preparation

Country Status (22)

Country Link
JP (1) JPS569498B2 (fr)
AR (1) AR208548A1 (fr)
AT (1) AT341488B (fr)
BE (1) BE815273A (fr)
CA (1) CA1048549A (fr)
CH (1) CH605606A5 (fr)
DE (1) DE2522218C3 (fr)
DK (1) DK145779C (fr)
ES (1) ES437790A1 (fr)
FI (1) FI61182C (fr)
FR (1) FR2271811B1 (fr)
GB (2) GB1467740A (fr)
HU (1) HU173890B (fr)
IE (1) IE41032B1 (fr)
IT (1) IT1049427B (fr)
NL (1) NL172120C (fr)
NO (1) NO139733C (fr)
OA (1) OA05004A (fr)
SE (1) SE434262B (fr)
SU (1) SU1292666A3 (fr)
YU (1) YU39318B (fr)
ZA (1) ZA752863B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4201725A (en) * 1974-05-20 1980-05-06 Labaz Secondary amines
GR61148B (en) * 1976-06-03 1978-09-27 Labaz Preparation process of active methylamine derivatives
JPS5427369A (en) * 1977-08-01 1979-03-01 Hitachi Ltd Pattern formation method
FR2470758A1 (fr) 1979-12-07 1981-06-12 Sanofi Sa Procede pour la fixation de groupes alkyles sur une chaine carbonee portant un groupe fonctionnel
WO2001008685A1 (fr) * 1999-07-30 2001-02-08 Vertex Pharmaceuticals Incorporated Derives d'amines acycliques et cycliques
CN114235991A (zh) * 2021-11-27 2022-03-25 山东省烟台市农业科学研究院 一种测定仲丁胺含量的高效液相色谱法

Also Published As

Publication number Publication date
FR2271811A1 (fr) 1975-12-19
FR2271811B1 (fr) 1978-08-04
CH605606A5 (fr) 1978-09-29
GB1467739A (en) 1977-03-23
ES437790A1 (es) 1977-05-16
GB1467740A (en) 1977-03-23
SE7505606L (sv) 1975-11-21
FI61182B (fi) 1982-02-26
AR208548A1 (es) 1977-02-15
DK216575A (da) 1975-11-21
YU122675A (en) 1982-02-28
IT1049427B (it) 1981-01-20
YU39318B (en) 1984-10-31
DE2522218A1 (de) 1975-12-04
AU8102175A (en) 1976-11-11
NO139733B (no) 1979-01-22
DK145779B (da) 1983-02-28
SU1292666A3 (ru) 1987-02-23
NL172120C (nl) 1983-07-18
JPS569498B2 (fr) 1981-03-02
HU173890B (hu) 1979-09-28
ATA371575A (de) 1977-06-15
NO751771L (fr) 1975-11-21
JPS514108A (fr) 1976-01-14
IE41032B1 (en) 1979-10-10
ZA752863B (en) 1976-04-28
NL172120B (nl) 1983-02-16
OA05004A (fr) 1980-12-31
DK145779C (da) 1983-08-22
IE41032L (en) 1975-10-20
FI61182C (fi) 1982-06-10
NO139733C (no) 1979-05-02
SE434262B (sv) 1984-07-16
DE2522218C3 (de) 1981-04-02
NL7505853A (nl) 1975-11-24
AT341488B (de) 1978-02-10
BE815273A (fr) 1974-11-20
DE2522218B2 (de) 1980-07-10
FI751468A (fr) 1975-11-21

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